IKZF1 and C8orf33

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF1	C8orf33
Gene Name		IKAROS family zinc finger 1 (Ikaros)	chromosome 8 open reading frame 33
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Pericentric Heterochromatin Cytoplasm Protein Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation Transcription, DNA-templated Cell Cycle Mesoderm Development Chromatin Modification B Cell Differentiation T Cell Differentiation Forebrain Development Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Thymus Development Peyer's Patch Development Positive Regulation Of NK T Cell Differentiation Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23512250 19684603 19684604) Crohn's disease ( 21102463) Hippocampal atrophy ( 19668339) IgG glycosylation ( 23382691) Inflammatory bowel disease ( 23128233) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517) Systemic lupus erythematosus ( 23273568 19838193)
Protein-Protein Interactions		75 interactors: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C19orf66 C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 CTBP2 DCX DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FRMD6 GLRX3 GMCL1P1 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MTA1 NEK6 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I WTAP ZMAT2 ZNF417 ZNF581	41 interactors: AAMP ALAS1 APP BLOC1S2 BRD4 CEP70 CRELD2 DVL3 EDRF1 EPS8 FAM9B FEZ1 FST FYN GIT1 GPRASP1 HAP1 HMBOX1 IKZF1 IMMT KBTBD7 KCTD6 KRTAP10-7 LZTS2 MDFI MRFAP1 NGEF NOL7 PI4KA PNMA1 RASSF1 SF3B2 TAOK1 TRIM23 TUBA1A TUBB2B WIZ ZC3H15 ZFP28 ZNF205 ZNF331
Entrez ID		10320	65265
HPRD ID		04318	07951
Ensembl ID		ENSG00000185811	ENSG00000182307
Uniprot IDs		Q13422	Q9H7E9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Organelle Organization Chromosome Organization Chromatin Modification Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA Repair Regulation Of Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Metabolic Process Regulation Of Cell Cycle Phase Transition RNA Splicing	Cell Cycle Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Positive Regulation Of Metabolic Process Cytoskeleton-dependent Intracellular Transport Regulation Of Signaling Axon Cargo Transport Regulation Of Cell Cycle Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Axon Guidance Positive Regulation Of Cell Cycle Process Locomotion Positive Regulation Of Signal Transduction Ephrin Receptor Signaling Pathway Regulation Of Cellular Process Regulation Of Cell Morphogenesis Protein Polymerization Regulation Of Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of JNK Cascade Positive Regulation Of Cell Cycle Microtubule-based Process Anterograde Axon Cargo Transport Positive Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Axonogenesis Microtubule-based Transport Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Neuron Projection Development Intracellular Signal Transduction Cell Projection Organization Axon Development Cell Morphogenesis Involved In Neuron Differentiation System Development Cellular Protein Complex Assembly Generation Of Neurons Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Signal Transduction Chemotaxis Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Difference) ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Intersection) ?