GABARAPL1 and ATG4D

Number of citations of the paper that reports this interaction (PMID 19549685)
34

Data Source:
BioGRID (enzymatic study)

		GABARAPL1	ATG4D
Gene Name		GABA(A) receptor-associated protein like 1	autophagy related 4D, cysteine peptidase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Extrinsic Component Of Membrane Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body	Cytoplasm Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding Microtubule Binding Tat Protein Binding Beta-tubulin Binding GABA Receptor Binding	Cysteine-type Endopeptidase Activity
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Nucleophagy Membrane Fusion	Autophagic Vacuole Assembly Mitochondrion Degradation C-terminal Protein Lipidation Proteolysis Protein Targeting To Membrane Apoptotic Process Cellular Response To Nitrogen Starvation Protein Processing Nucleophagy Protein Delipidation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: AHNAK2 ATG4A ATG4B ATG4D CALCOCO2 DVL2 FAM134C FUNDC1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAPK15 OPRK1 RABGAP1 RABGAP1L SCYL3 SNCA SQSTM1 SRPK1 SRPK2 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 VDR	4 interactors: CASP3 CASP8 GABARAPL1 GABARAPL2
Entrez ID		23710	84971
HPRD ID		07601	07005
Ensembl ID		ENSG00000139112	ENSG00000130734
Uniprot IDs		Q9H0R8	B4DGM8 Q86TL0
PDB IDs		2L8J 2R2Q
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Autophagy Regulation Of Catalytic Activity Regulation Of Signal Transduction Regulation Of Signaling Protein Delipidation Mitochondrion Degradation Organelle Disassembly Regulation Of Metabolic Process Macroautophagy Cellular Response To Nitrogen Starvation Retrograde Transport, Endosome To Golgi Cellular Response To Nutrient Levels Nucleophagy Response To Starvation C-terminal Protein Lipidation Endosomal Transport Cellular Response To Extracellular Stimulus Protein Processing Response To Nutrient Levels Positive Regulation Of Autophagy Response To Extracellular Stimulus Autophagic Vacuole Assembly Cellular Response To Starvation Negative Regulation Of Viral Genome Replication Regulation Of Viral Genome Replication Mitochondrion Organization Negative Regulation Of Viral Process Vacuole Organization Regulation Of Autophagy Positive Regulation Of Viral Genome Replication Protein Lipidation Intracellular Transport Lipoprotein Biosynthetic Process Cellular Localization Response To Stress Establishment Of Localization In Cell Positive Regulation Of Protein Metabolic Process	Nucleophagy Mitochondrion Degradation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Organelle Disassembly Mitochondrion Organization Autophagic Vacuole Assembly Macroautophagy Catabolic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Extrinsic Apoptotic Signaling Pathway Zymogen Activation Vacuole Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Response To Tumor Necrosis Factor Membrane Fusion Positive Regulation Of Endopeptidase Activity Cellular Response To Starvation Positive Regulation Of Peptidase Activity Autophagy Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Positive Regulation Of Hydrolase Activity Cellular Response To Nutrient Levels Response To Starvation Intrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Response To Stress TRAIL-activated Apoptotic Signaling Pathway Cellular Response To Extracellular Stimulus Protein Processing Myeloid Cell Differentiation Positive Regulation Of Proteolysis Cellular Response To Stress Positive Regulation Of Catalytic Activity Glial Cell Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Apoptotic Signaling Pathway Regulation Of Endopeptidase Activity Response To External Stimulus Regulation Of Peptidase Activity Response To Nutrient Levels Positive Regulation Of Macrophage Differentiation Cellular Component Assembly Negative Regulation Of Activated T Cell Proliferation Response To Cobalt Ion
Tagcloud ?		2000mug 3f aminobutyric anabolism atg12 atg13 atg5 atrogin atrogin1 autophagosome beta2 bnip3 culminated e1b eb eif3 formoterol hydrolases kinase1 lc3b mafbx myod protein3 relativized sqstm1 tfeb tibialis ulk1 unc
Tagcloud (Difference) ?		2000mug 3f aminobutyric anabolism atg12 atg13 atg5 atrogin atrogin1 autophagosome beta2 bnip3 culminated e1b eb eif3 formoterol hydrolases kinase1 lc3b mafbx myod protein3 relativized sqstm1 tfeb tibialis ulk1 unc
Tagcloud (Intersection) ?