GABARAPL1 and ATG4A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GABARAPL1	ATG4A
Description		GABA type A receptor associated protein like 1	autophagy related 4A cysteine peptidase
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GO Annotations	Cellular Component	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Cilium Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Ciliary Basal Body	Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding Phosphatidylethanolamine Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Protein-phosphatidylethanolamide Deconjugating Activity
	Biological Process	Autophagosome Assembly Mitophagy Autophagy Cellular Response To Nitrogen Starvation Glycophagy Autophagosome Maturation	Autophagosome Assembly Mitophagy Proteolysis Lipid Metabolic Process Autophagy Protein Transport Protein Processing Piecemeal Microautophagy Of The Nucleus Aggrephagy Protein Delipidation
Pathways		Macroautophagy	Macroautophagy
Drugs
Diseases
GWAS
Interacting Genes		87 interacting genes: AHNAK2 AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG4A ATG4B ATG4D AZI2 BICC1 BNIP3L BRD9 BSCL2 BSDC1 CALCOCO1 CALCOCO2 CARS2 CCT2 CDC37 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 G3BP1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAP4K2 MAPK15 MEFV MLX MYBPC1 NCOR1 NEDD4 NFIA NUFIP2 OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RESF1 RETREG3 SCYL3 SEC62 SNCA SQSTM1 SRPK1 SRPK2 STK3 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM25 TRIM32 UMAD1 VDR WDFY3 ZBTB22	5 interacting genes: ATG101 CDKL3 GABARAPL1 GABARAPL2 MAP1LC3B
Entrez ID		23710	115201
HPRD ID		07601	06455
Ensembl ID		ENSG00000139112	ENSG00000101844
Uniprot IDs		Q9H0R8	B4DEA4 Q8WYN0
PDB IDs		2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL 6YOO 7AA7 7AA9 7JHX 8X8A	2P82
Enriched GO Terms of Interacting Partners?		Autophagosome Regulation Of Cilium Assembly Autophagy Macroautophagy GTPase Activator Activity Regulation Of Organelle Assembly Cytosol Regulation Of Autophagy Positive Regulation Of Autophagy Autophagy Of Mitochondrion Regulation Of Cell Projection Assembly Mitophagy Autophagosome Assembly Autophagosome Organization Aggrephagy Cytoplasmic Vesicle Piecemeal Microautophagy Of The Nucleus Cytoplasm Regulation Of Cell Projection Organization Microautophagy Nucleophagy Positive Regulation Of Catabolic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Vacuole Organization Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Protein-phosphatidylethanolamide Deconjugating Activity Catabolic Process Protein Delipidation Response To Mitochondrial Depolarisation Organelle Assembly Regulation Of Macroautophagy Atg1/ULK1 Kinase Complex Regulation Of Cellular Component Organization Positive Regulation Of Macroautophagy Regulation Of Intracellular Signal Transduction Protein Polyubiquitination Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Signal Transduction Phagophore Assembly Site Negative Regulation Of Signal Transduction ERBB3:ERBB2 Complex Protein Localization To Phagocytic Vesicle Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Response To Stress Regulation Of Signaling Regulation Of Cell Communication Negative Regulation Of Viral Process	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Assembly Autophagosome Organization Vacuole Organization Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Autophagy Of Mitochondrion Autophagosome Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy GABA Receptor Binding Cellular Response To Starvation Organelle Assembly Response To Starvation Cellular Response To Nutrient Levels Ubiquitin Protein Ligase Binding Beta-tubulin Binding Response To Nutrient Levels Catabolic Process Cytoplasmic Vesicle Cellular Component Assembly Organelle Organization Microtubule Binding Atg1/ULK1 Kinase Complex Ceramide Binding Tat Protein Binding Dendrite Extension Glycophagy Microtubule Protein Localization To Endoplasmic Reticulum Protein-containing Complex Organization Positive Regulation Of ATP-dependent Activity Glycogen Catabolic Process Cellular Response To Stress Polysaccharide Catabolic Process Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Axon Extension Phagophore Assembly Site Intra-Golgi Vesicle-mediated Transport Regulation Of ATP-dependent Activity Positive Regulation Of Dendrite Morphogenesis Cytoplasm Organelle Membrane
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