GABARAPL1 and ZBTB22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GABARAPL1	ZBTB22
Description		GABA type A receptor associated protein like 1	zinc finger and BTB domain containing 22
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Cilium Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Ciliary Basal Body	Chromatin Nucleus
	Molecular Function	Protein Binding Phospholipid Binding Phosphatidylethanolamine Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Autophagosome Assembly Mitophagy Autophagy Cellular Response To Nitrogen Starvation Glycophagy Autophagosome Maturation	Regulation Of Transcription By RNA Polymerase II
Pathways		Macroautophagy
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Walking pace ( 33128006)
Interacting Genes		87 interacting genes: AHNAK2 AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG4A ATG4B ATG4D AZI2 BICC1 BNIP3L BRD9 BSCL2 BSDC1 CALCOCO1 CALCOCO2 CARS2 CCT2 CDC37 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 G3BP1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAP4K2 MAPK15 MEFV MLX MYBPC1 NCOR1 NEDD4 NFIA NUFIP2 OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RESF1 RETREG3 SCYL3 SEC62 SNCA SQSTM1 SRPK1 SRPK2 STK3 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM25 TRIM32 UMAD1 VDR WDFY3 ZBTB22	16 interacting genes: AP4M1 CCDC13 DNAJA3 DRC4 FXR2 GABARAPL1 GATA1 MCRS1 MEMO1 MLLT6 PIN1 RBM39 TCEA2 UBQLN4 VAPA VAPB
Entrez ID		23710	9278
HPRD ID		07601	15761
Ensembl ID		ENSG00000139112	ENSG00000236104
Uniprot IDs		Q9H0R8	A0A1U9X8V3 O15209
PDB IDs		2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL 6YOO 7AA7 7AA9 7JHX 8X8A
Enriched GO Terms of Interacting Partners?		Autophagosome Regulation Of Cilium Assembly Autophagy Macroautophagy GTPase Activator Activity Regulation Of Organelle Assembly Cytosol Regulation Of Autophagy Positive Regulation Of Autophagy Autophagy Of Mitochondrion Regulation Of Cell Projection Assembly Mitophagy Autophagosome Assembly Autophagosome Organization Aggrephagy Cytoplasmic Vesicle Piecemeal Microautophagy Of The Nucleus Cytoplasm Regulation Of Cell Projection Organization Microautophagy Nucleophagy Positive Regulation Of Catabolic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Vacuole Organization Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Protein-phosphatidylethanolamide Deconjugating Activity Catabolic Process Protein Delipidation Response To Mitochondrial Depolarisation Organelle Assembly Regulation Of Macroautophagy Atg1/ULK1 Kinase Complex Regulation Of Cellular Component Organization Positive Regulation Of Macroautophagy Regulation Of Intracellular Signal Transduction Protein Polyubiquitination Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Signal Transduction Phagophore Assembly Site Negative Regulation Of Signal Transduction ERBB3:ERBB2 Complex Protein Localization To Phagocytic Vesicle Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Response To Stress Regulation Of Signaling Regulation Of Cell Communication Negative Regulation Of Viral Process	FFAT Motif Binding COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Endoplasmic Reticulum Localization Host-mediated Activation Of Viral Genome Replication Host-mediated Perturbation Of Viral Genome Replication Host-mediated Suppression Of Viral Genome Replication Organelle Organization Ciliary Basal Body Centriolar Satellite Viral Release From Host Cell Endoplasmic Reticulum Exit Site Vesicle Budding From Membrane Protein-membrane Adaptor Activity Host-mediated Activation Of Viral Process Beta-tubulin Binding Cis-trans Isomerase Activity
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