GABARAPL1 and UMAD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GABARAPL1	UMAD1
Description		GABA type A receptor associated protein like 1	UBAP1-MVB12-associated (UMA) domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Cilium Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Protein Binding Phospholipid Binding Phosphatidylethanolamine Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	Protein Binding
	Biological Process	Autophagosome Assembly Mitophagy Autophagy Cellular Response To Nitrogen Starvation Glycophagy Autophagosome Maturation
Pathways		Macroautophagy
Drugs
Diseases
GWAS			Coffee consumption ( 31046077) Femur bone mineral density x serum urate levels interaction ( 34046847) Hip circumference adjusted for BMI ( 28552196) Interstitial lung diseases in rheumatoid arthritis ( 32737115) Intraocular pressure ( 30591961) Small cell lung carcinoma ( 28604730)
Interacting Genes		87 interacting genes: AHNAK2 AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG4A ATG4B ATG4D AZI2 BICC1 BNIP3L BRD9 BSCL2 BSDC1 CALCOCO1 CALCOCO2 CARS2 CCT2 CDC37 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 G3BP1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAP4K2 MAPK15 MEFV MLX MYBPC1 NCOR1 NEDD4 NFIA NUFIP2 OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RESF1 RETREG3 SCYL3 SEC62 SNCA SQSTM1 SRPK1 SRPK2 STK3 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM25 TRIM32 UMAD1 VDR WDFY3 ZBTB22	2 interacting genes: GABARAPL1 TH
Entrez ID		23710	729852
HPRD ID		07601
Ensembl ID		ENSG00000139112	ENSG00000219545
Uniprot IDs		Q9H0R8	C9J7I0
PDB IDs		2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL 6YOO 7AA7 7AA9 7JHX 8X8A
Enriched GO Terms of Interacting Partners?		Autophagosome Regulation Of Cilium Assembly Autophagy Macroautophagy GTPase Activator Activity Regulation Of Organelle Assembly Cytosol Regulation Of Autophagy Positive Regulation Of Autophagy Autophagy Of Mitochondrion Regulation Of Cell Projection Assembly Mitophagy Autophagosome Assembly Autophagosome Organization Aggrephagy Cytoplasmic Vesicle Piecemeal Microautophagy Of The Nucleus Cytoplasm Regulation Of Cell Projection Organization Microautophagy Nucleophagy Positive Regulation Of Catabolic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Vacuole Organization Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Protein-phosphatidylethanolamide Deconjugating Activity Catabolic Process Protein Delipidation Response To Mitochondrial Depolarisation Organelle Assembly Regulation Of Macroautophagy Atg1/ULK1 Kinase Complex Regulation Of Cellular Component Organization Positive Regulation Of Macroautophagy Regulation Of Intracellular Signal Transduction Protein Polyubiquitination Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Signal Transduction Phagophore Assembly Site Negative Regulation Of Signal Transduction ERBB3:ERBB2 Complex Protein Localization To Phagocytic Vesicle Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Response To Stress Regulation Of Signaling Regulation Of Cell Communication Negative Regulation Of Viral Process	Tyrosine 3-monooxygenase Activity Dopamine Biosynthetic Process From Tyrosine Serotonin Biosynthetic Process Epinephrine Biosynthetic Process Epinephrine Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Pteridine As One Donor, And Incorporation Of One Atom Of Oxygen Hyaloid Vascular Plexus Regression Synaptic Transmission, Dopaminergic Mating Behavior Serotonin Metabolic Process Melanosome Membrane Catecholamine Biosynthetic Process Anatomical Structure Regression Norepinephrine Biosynthetic Process Smooth Endoplasmic Reticulum Dopamine Biosynthetic Process Cytoplasmic Vesicle Norepinephrine Metabolic Process Embryonic Camera-type Eye Morphogenesis Tyrosine Metabolic Process Phosphatidylethanolamine Binding Cellular Response To Nitrogen Starvation GABA Receptor Binding Tat Protein Binding Glycogen Catabolic Process Glycophagy Polysaccharide Catabolic Process Embryonic Eye Morphogenesis Amine Biosynthetic Process Eating Behavior Eye Photoreceptor Cell Development Biogenic Amine Biosynthetic Process Reproductive Behavior Dopamine Metabolic Process Aromatic Amino Acid Metabolic Process Photoreceptor Cell Development Beta-tubulin Binding Catecholamine Metabolic Process Pigmentation Autophagosome Maturation Autophagosome Membrane Heart Morphogenesis Mitophagy Eye Morphogenesis Glycogen Metabolic Process Monooxygenase Activity Biogenic Amine Metabolic Process Sensory Organ Morphogenesis Energy Reserve Metabolic Process Polysaccharide Metabolic Process
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