Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
KRTAP4-12 and GNE
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRTAP4-12
GNE
Gene Name
keratin associated protein 4-12
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Cytoplasm
Cytosol
Molecular Function
Protein Binding
Hydrolase Activity, Hydrolyzing O-glycosyl Compounds
ATP Binding
UDP-N-acetylglucosamine 2-epimerase Activity
N-acylmannosamine Kinase Activity
Metal Ion Binding
Biological Process
N-acetylglucosamine Biosynthetic Process
UDP-N-acetylglucosamine Metabolic Process
N-acetylneuraminate Metabolic Process
Dolichol-linked Oligosaccharide Biosynthetic Process
Cell Adhesion
Protein N-linked Glycosylation Via Asparagine
Post-translational Protein Modification
Cellular Protein Metabolic Process
Carbohydrate Phosphorylation
Pathways
Diseases of glycosylation
Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
Defective MGAT2 causes MGAT2-CDG (CDG-2a)
Defective ALG1 causes ALG1-CDG (CDG-1k)
Defective MOGS causes MOGS-CDG (CDG-2b)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Defective ALG9 causes ALG9-CDG (CDG-1l)
Defective MAN1B1 causes MRT15
Defective ALG11 causes ALG11-CDG (CDG-1p)
Defective ALG2 causes ALG2-CDG (CDG-1i)
Post-translational protein modification
Defective ALG3 causes ALG3-CDG (CDG-1d)
Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
Synthesis of substrates in N-glycan biosythesis
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective ALG6 causes ALG6-CDG (CDG-1c)
Defective RFT1 causes RFT1-CDG (CDG-1n)
Asparagine N-linked glycosylation
Defective ALG8 causes ALG8-CDG (CDG-1h)
Sialic acid metabolism
Defective MPDU1 causes MPDU1-CDG (CDG-1f)
Defective ALG12 causes ALG12-CDG (CDG-1g)
Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions
107 interactors:
ADAMTSL4
ALPP
AQP1
ATG12
ATN1
BAHD1
BEX2
C10orf62
C19orf66
CATSPER1
CBX2
CCDC116
CCDC185
CCNK
CDC42EP1
CHCHD3
CHIC2
CLDN2
CNNM3
CNTFR
COL8A1
CRCT1
CREB5
CRY1
DBF4B
DLK2
EIF4E2
FAM107A
FAM27E3
FAM76B
FBXL18
FBXW5
GLRX3
GNE
GPATCH2L
GPRIN2
GRAP2
HHEX
HOXA1
HOXB9
IFI30
ILF3
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP26-1
KRTAP3-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2D
LCE3E
LCE4A
LINGO1
LNX1
MAPKBP1
MEOX2
MRPL4
NOTCH2NL
NPDC1
NUDT18
NUFIP2
OTX1
PCSK5
PDGFRB
PFKL
PHLDA1
PLSCR1
PLSCR4
PNKP
PRKAB2
PRR13
QPRT
RERE
RPS28
SLC25A10
SLC25A6
SMCP
SPATA3
SPG7
SPRY2
TAP1
TBC1D16
TBC1D23
TCEB3B
THAP10
THAP7
TOP3B
TXNDC5
ZBTB16
ZNF165
ZNF20
ZNF250
ZNF408
ZNF415
ZNF417
ZNF426
ZNF439
ZNF440
ZNF581
ZNF638
ZNF655
ZNF764
ZSCAN26
17 interactors:
ADAMTSL4
CRMP1
GTPBP3
KIAA1549
KRT31
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-12
KRTAP5-9
KRTAP9-2
NOTCH2NL
RIF1
SPRY2
ZBTB16
Entrez ID
83755
10020
HPRD ID
13941
04825
Ensembl ID
ENSG00000213416
ENSG00000159921
Uniprot IDs
Q9BQ66
H0YFA7
Q9Y223
PDB IDs
2YHW
2YHY
2YI1
3EO3
Enriched GO Terms of Interacting Partners
?
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Biosynthetic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Keratinization
Anterior/posterior Pattern Specification
Regulation Of Cellular Process
Regulation Of Metabolic Process
Cellular Process
Keratinocyte Differentiation
Embryo Development
Phospholipid Scrambling
Metanephric Glomerulus Vasculature Development
Pattern Specification Process
Metanephric Glomerulus Development
Epidermal Cell Differentiation
Epidermis Development
Mitochondrion Organization
Metabolic Process
Forebrain Morphogenesis
Transcription From RNA Polymerase II Promoter
Glomerulus Vasculature Development
Multicellular Organismal Development
Organic Anion Transport
Inner Ear Development
Cell Migration Involved In Coronary Angiogenesis
Hepatic Duct Development
Abducens Nerve Formation
Metanephric Mesenchymal Cell Migration
Transepithelial Water Transport
Renin Secretion Into Blood Stream
Metanephric Descending Thin Limb Development
DGDP Catabolic Process
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Tagcloud
?
15s
alphap
competition
contaminant
doublet
eif2
eif2alpha
eif2b
exchange
gdp
germ
gtp
guanine
heme
impairs
inability
insects
interact
lysates
nucleotides
p41
presumably
residue
reticulocyte
unable
unlike
wg
wheat
x
Tagcloud (Difference)
?
15s
alphap
competition
contaminant
doublet
eif2
eif2alpha
eif2b
exchange
gdp
germ
gtp
guanine
heme
impairs
inability
insects
interact
lysates
nucleotides
p41
presumably
residue
reticulocyte
unable
unlike
wg
wheat
x
Tagcloud (Intersection)
?