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GNE and KRTAP10-7
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
GNE
KRTAP10-7
Gene Name
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
keratin associated protein 10-7
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Keratin Filament
Molecular Function
Hydrolase Activity, Hydrolyzing O-glycosyl Compounds
ATP Binding
UDP-N-acetylglucosamine 2-epimerase Activity
N-acylmannosamine Kinase Activity
Metal Ion Binding
Biological Process
N-acetylglucosamine Biosynthetic Process
UDP-N-acetylglucosamine Metabolic Process
N-acetylneuraminate Metabolic Process
Dolichol-linked Oligosaccharide Biosynthetic Process
Cell Adhesion
Protein N-linked Glycosylation Via Asparagine
Post-translational Protein Modification
Cellular Protein Metabolic Process
Carbohydrate Phosphorylation
Pathways
Diseases of glycosylation
Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
Defective MGAT2 causes MGAT2-CDG (CDG-2a)
Defective ALG1 causes ALG1-CDG (CDG-1k)
Defective MOGS causes MOGS-CDG (CDG-2b)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Defective ALG9 causes ALG9-CDG (CDG-1l)
Defective MAN1B1 causes MRT15
Defective ALG11 causes ALG11-CDG (CDG-1p)
Defective ALG2 causes ALG2-CDG (CDG-1i)
Post-translational protein modification
Defective ALG3 causes ALG3-CDG (CDG-1d)
Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
Synthesis of substrates in N-glycan biosythesis
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective ALG6 causes ALG6-CDG (CDG-1c)
Defective RFT1 causes RFT1-CDG (CDG-1n)
Asparagine N-linked glycosylation
Defective ALG8 causes ALG8-CDG (CDG-1h)
Sialic acid metabolism
Defective MPDU1 causes MPDU1-CDG (CDG-1f)
Defective ALG12 causes ALG12-CDG (CDG-1g)
Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions
17 interactors:
ADAMTSL4
CRMP1
GTPBP3
KIAA1549
KRT31
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-12
KRTAP5-9
KRTAP9-2
NOTCH2NL
RIF1
SPRY2
ZBTB16
215 interactors:
AEN
AES
ALDH3B1
ANKRD36BP1
AP1M1
APP
AQP1
AVPI1
B4GALT7
BAHD1
BCL6B
BMP7
BUD31
BYSL
C16orf59
C19orf57
C19orf66
C8orf33
C9orf9
CARHSP1
CARKD
CATIP
CBX2
CCDC185
CCDC26
CCNG1
CDCA7L
CHIC2
CHRD
CHRNG
CLK1
CLK4
COL8A1
CRCT1
CREB5
CSNK1G1
CSNK1G2
CTNNBIP1
CTRC
CXCL16
DAAM2
DERL2
DHX57
DMRT3
E2F6
E4F1
EHHADH
FAM124B
FAM161A
FAM27E3
FAM74A4
FAM76B
FARS2
GABARAPL1
GABARAPL2
GEM
GLIDR
GLP1R
GNE
GOLGA8EP
GRN
GSTP1
GUCD1
HBZ
HHEX
HPCAL1
HSBP1
HSD3B7
IGSF8
ING5
INPP5D
IQUB
KLHL38
KRT20
KRT83
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP4-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2A
LCE3E
LCE4A
LIMS2
LINC00242
LMNA
LMO2
LRCH4
MAPKBP1
MCM5
MOBP
MRGBP
MXD3
MXI1
NAA10
NOL12
NOTCH2NL
NPBWR2
NPDC1
NUBP2
NUDCD3
NUFIP2
P2RY6
PCED1A
PCSK5
PDIA5
PDLIM5
PFKL
PIN1
POLL
POM121L8P
PPARD
PRKAB2
PRM2
PRR13
PTGDS
PTGER3
PTPMT1
PVR
PVRL2
PVRL3
RNF175
RPF1
RPL11
RPL36AL
RPS28
RPUSD3
RSPO2
RTN4RL1
RWDD2B
SCNM1
SDCBP
SLC23A1
SLC25A48
SLC6A20
SMCO4
SMCP
SPATA3
SPATA8
SPG7
SPRY1
SSX2IP
STK16
SUV39H1
TAPBPL
TCEA2
TCEANC
THAP1
THAP6
TMA16
TMEM8A
TNP2
TNS2
TOR1A
TREX1
TRIM42
TULP3
TXNDC5
TYRO3
UCP2
UXT
VTI1B
WDYHV1
WNT11
ZBTB24
ZBTB38
ZBTB9
ZFYVE26
ZNF101
ZNF124
ZNF133
ZNF155
ZNF165
ZNF169
ZNF175
ZNF180
ZNF2
ZNF20
ZNF223
ZNF250
ZNF26
ZNF266
ZNF32
ZNF320
ZNF329
ZNF337
ZNF41
ZNF417
ZNF418
ZNF419
ZNF425
ZNF433
ZNF439
ZNF490
ZNF543
ZNF555
ZNF564
ZNF572
ZNF578
ZNF581
ZNF587
ZNF625
ZNF670
ZNF697
ZNF707
ZNF778
ZNF792
ZNF846
ZNHIT1
ZSCAN26
Entrez ID
10020
386675
HPRD ID
04825
11193
Ensembl ID
ENSG00000159921
ENSG00000205441
Uniprot IDs
H0YFA7
Q9Y223
P60409
PDB IDs
2YHW
2YHY
2YI1
3EO3
Enriched GO Terms of Interacting Partners
?
RNA Biosynthetic Process
Transcription, DNA-templated
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Cellular Metabolic Process
Cellular Process
Regulation Of Metabolic Process
Regulation Of Cellular Process
Susceptibility To T Cell Mediated Cytotoxicity
Transepithelial Transport
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Metabolic Process
Keratinization
Susceptibility To Natural Killer Cell Mediated Cytotoxicity
Developmental Process
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Negative Regulation Of Mesenchymal Cell Proliferation
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Negative Regulation Of Gene Expression
Cellular Response To Oxygen Levels
Cellular Response To Topologically Incorrect Protein
Cellular Response To Stress
Penetration Of Zona Pellucida
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Spinal Cord Dorsal/ventral Patterning
Positive Regulation Of Immune Response To Tumor Cell
Multicellular Organismal Development
Spinal Cord Patterning
Negative Regulation Of Cellular Metabolic Process
Respiratory Tube Development
Tagcloud
?
15s
alphap
competition
contaminant
doublet
eif2
eif2alpha
eif2b
exchange
gdp
germ
gtp
guanine
heme
impairs
inability
insects
interact
lysates
nucleotides
p41
presumably
residue
reticulocyte
unable
unlike
wg
wheat
x
Tagcloud (Difference)
?
15s
alphap
competition
contaminant
doublet
eif2
eif2alpha
eif2b
exchange
gdp
germ
gtp
guanine
heme
impairs
inability
insects
interact
lysates
nucleotides
p41
presumably
residue
reticulocyte
unable
unlike
wg
wheat
x
Tagcloud (Intersection)
?