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KRTAP4-12 and CCNK
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
KRTAP4-12
CCNK
Gene Name
keratin associated protein 4-12
cyclin K
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Cyclin K-CDK12 Complex
Cyclin K-CDK13 Complex
Nucleus
Molecular Function
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
Protein Kinase Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
In Utero Embryonic Development
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Mitotic Nuclear Division
Cell Division
Negative Regulation Of Cell Cycle Arrest
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
107 interactors:
ADAMTSL4
ALPP
AQP1
ATG12
ATN1
BAHD1
BEX2
C10orf62
C19orf66
CATSPER1
CBX2
CCDC116
CCDC185
CCNK
CDC42EP1
CHCHD3
CHIC2
CLDN2
CNNM3
CNTFR
COL8A1
CRCT1
CREB5
CRY1
DBF4B
DLK2
EIF4E2
FAM107A
FAM27E3
FAM76B
FBXL18
FBXW5
GLRX3
GNE
GPATCH2L
GPRIN2
GRAP2
HHEX
HOXA1
HOXB9
IFI30
ILF3
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP26-1
KRTAP3-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2D
LCE3E
LCE4A
LINGO1
LNX1
MAPKBP1
MEOX2
MRPL4
NOTCH2NL
NPDC1
NUDT18
NUFIP2
OTX1
PCSK5
PDGFRB
PFKL
PHLDA1
PLSCR1
PLSCR4
PNKP
PRKAB2
PRR13
QPRT
RERE
RPS28
SLC25A10
SLC25A6
SMCP
SPATA3
SPG7
SPRY2
TAP1
TBC1D16
TBC1D23
TCEB3B
THAP10
THAP7
TOP3B
TXNDC5
ZBTB16
ZNF165
ZNF20
ZNF250
ZNF408
ZNF415
ZNF417
ZNF426
ZNF439
ZNF440
ZNF581
ZNF638
ZNF655
ZNF764
ZSCAN26
26 interactors:
AES
ATXN1
BHLHE40
CCDC85B
CDK18
CDK2
CDK9
CEP76
DVL3
EFEMP2
FKBP6
HMG20A
KCNRG
KRTAP4-12
LZTS2
NDC80
NECAB2
PIN1
POLR2A
RBPMS
RFX6
RHOXF2
STX11
TSC22D4
UBC
USHBP1
Entrez ID
83755
8812
HPRD ID
13941
10352
Ensembl ID
ENSG00000213416
Uniprot IDs
Q9BQ66
O75909
PDB IDs
2I53
Enriched GO Terms of Interacting Partners
?
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Biosynthetic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Keratinization
Anterior/posterior Pattern Specification
Regulation Of Cellular Process
Regulation Of Metabolic Process
Cellular Process
Keratinocyte Differentiation
Embryo Development
Phospholipid Scrambling
Metanephric Glomerulus Vasculature Development
Pattern Specification Process
Metanephric Glomerulus Development
Epidermal Cell Differentiation
Epidermis Development
Mitochondrion Organization
Metabolic Process
Forebrain Morphogenesis
Transcription From RNA Polymerase II Promoter
Glomerulus Vasculature Development
Multicellular Organismal Development
Organic Anion Transport
Inner Ear Development
Cell Migration Involved In Coronary Angiogenesis
Hepatic Duct Development
Abducens Nerve Formation
Metanephric Mesenchymal Cell Migration
Transepithelial Water Transport
Renin Secretion Into Blood Stream
Metanephric Descending Thin Limb Development
DGDP Catabolic Process
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Wnt Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle Process
Regulation Of Ubiquitin-protein Transferase Activity
Heterocycle Metabolic Process
Regulation Of Cell Cycle Arrest
Cellular Aromatic Compound Metabolic Process
Gene Expression
Regulation Of Metabolic Process
Regulation Of Wnt Signaling Pathway
Regulation Of Cell Cycle
Cell Cycle
Cellular Nitrogen Compound Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cellular Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Mitotic Cell Cycle Process
Positive Regulation Of Gene Expression
Negative Regulation Of Signal Transduction
PiRNA Metabolic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Mitotic Cell Cycle
Biosynthetic Process
Negative Regulation Of Signaling
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Viral Transcription
Regulation Of Protein Ubiquitination
Tagcloud
?
affects
associate
bulk
cdk12
cdk13
cdk9
cdks
ctd
elongation
far
flag
hct116
heptad
implementing
numerous
paralog
partner
phosphorylate
preferentially
processing
repeat
reveals
rna
sec
seq
snorna
super
tagged
tefb
Tagcloud (Difference)
?
affects
associate
bulk
cdk12
cdk13
cdk9
cdks
ctd
elongation
far
flag
hct116
heptad
implementing
numerous
paralog
partner
phosphorylate
preferentially
processing
repeat
reveals
rna
sec
seq
snorna
super
tagged
tefb
Tagcloud (Intersection)
?