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KRTAP4-12 and LINGO1
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
KRTAP4-12
LINGO1
Gene Name
keratin associated protein 4-12
leucine rich repeat and Ig domain containing 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
Epidermal Growth Factor Receptor Binding
Biological Process
Central Nervous System Neuron Development
Neuron Projection Development
Protein Kinase B Signaling
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Oligodendrocyte Differentiation
Regulation Of Axonogenesis
Negative Regulation Of Axonogenesis
Pathways
Signalling by NGF
Axonal growth inhibition (RHOA activation)
p75NTR regulates axonogenesis
p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Essential tremor (
19182806
)
Protein-Protein Interactions
107 interactors:
ADAMTSL4
ALPP
AQP1
ATG12
ATN1
BAHD1
BEX2
C10orf62
C19orf66
CATSPER1
CBX2
CCDC116
CCDC185
CCNK
CDC42EP1
CHCHD3
CHIC2
CLDN2
CNNM3
CNTFR
COL8A1
CRCT1
CREB5
CRY1
DBF4B
DLK2
EIF4E2
FAM107A
FAM27E3
FAM76B
FBXL18
FBXW5
GLRX3
GNE
GPATCH2L
GPRIN2
GRAP2
HHEX
HOXA1
HOXB9
IFI30
ILF3
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP26-1
KRTAP3-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2D
LCE3E
LCE4A
LINGO1
LNX1
MAPKBP1
MEOX2
MRPL4
NOTCH2NL
NPDC1
NUDT18
NUFIP2
OTX1
PCSK5
PDGFRB
PFKL
PHLDA1
PLSCR1
PLSCR4
PNKP
PRKAB2
PRR13
QPRT
RERE
RPS28
SLC25A10
SLC25A6
SMCP
SPATA3
SPG7
SPRY2
TAP1
TBC1D16
TBC1D23
TCEB3B
THAP10
THAP7
TOP3B
TXNDC5
ZBTB16
ZNF165
ZNF20
ZNF250
ZNF408
ZNF415
ZNF417
ZNF426
ZNF439
ZNF440
ZNF581
ZNF638
ZNF655
ZNF764
ZSCAN26
8 interactors:
EFEMP2
FBXW7
GOLGA2
KRTAP4-12
NGFR
RTN4R
SPAG5
TRIM27
Entrez ID
83755
84894
HPRD ID
13941
14322
Ensembl ID
ENSG00000213416
ENSG00000169783
Uniprot IDs
Q9BQ66
Q96FE5
PDB IDs
2ID5
Enriched GO Terms of Interacting Partners
?
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Biosynthetic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Keratinization
Anterior/posterior Pattern Specification
Regulation Of Cellular Process
Regulation Of Metabolic Process
Cellular Process
Keratinocyte Differentiation
Embryo Development
Phospholipid Scrambling
Metanephric Glomerulus Vasculature Development
Pattern Specification Process
Metanephric Glomerulus Development
Epidermal Cell Differentiation
Epidermis Development
Mitochondrion Organization
Metabolic Process
Forebrain Morphogenesis
Transcription From RNA Polymerase II Promoter
Glomerulus Vasculature Development
Multicellular Organismal Development
Organic Anion Transport
Inner Ear Development
Cell Migration Involved In Coronary Angiogenesis
Hepatic Duct Development
Abducens Nerve Formation
Metanephric Mesenchymal Cell Migration
Transepithelial Water Transport
Renin Secretion Into Blood Stream
Metanephric Descending Thin Limb Development
DGDP Catabolic Process
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Negative Regulation Of Axonogenesis
Negative Regulation Of SREBP Signaling Pathway
Negative Regulation Of Cell Morphogenesis Involved In Differentiation
Negative Regulation Of Neuron Projection Development
Negative Regulation Of Triglyceride Biosynthetic Process
Negative Regulation Of Interleukin-2 Secretion
Negative Regulation Of Cell Projection Organization
Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Hair Follicle Development
Regulation Of Axonogenesis
Negative Regulation Of Hepatocyte Proliferation
Negative Regulation Of Hair Cycle
Positive Regulation Of Odontogenesis Of Dentin-containing Tooth
Regulation Of Protein Localization
Regulation Of Organ Morphogenesis
Regulation Of Cellular Component Organization
Negative Regulation Of Neuron Differentiation
Negative Regulation Of DNA Endoreduplication
Positive Regulation Of Apoptotic Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Calcium Ion Import
Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Neurotrophin Signaling Pathway
Chromosome Segregation
Positive Regulation Of Oxidative Stress-induced Cell Death
Interferon-gamma Secretion
Regulation Of DNA Endoreduplication
Negative Regulation Of Neurogenesis
Regulation Of Hepatocyte Proliferation
Positive Regulation Of Odontogenesis
Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Development
Negative Regulation Of Viral Release From Host Cell
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Regulation Of Odontogenesis Of Dentin-containing Tooth
Regulation Of Neuron Projection Development
Membrane Protein Intracellular Domain Proteolysis
Regulation Of Hair Follicle Development
Cell Cycle
Regulation Of Triglyceride Biosynthetic Process
Interferon-gamma Production
Negative Regulation Of Interleukin-2 Production
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Glucose Import In Response To Insulin Stimulus
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Viral Transcription
Regulation Of Hair Cycle
Regulation Of Viral Release From Host Cell
Regulation Of Calcium Ion Import
Negative Regulation Of Cell Cycle
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