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KRTAP4-12 and TAP1
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
KRTAP4-12
TAP1
Gene Name
keratin associated protein 4-12
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Mitochondrion
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Endoplasmic Reticulum Membrane
TAP Complex
Molecular Function
Protein Binding
Protein Binding
ATP Binding
Peptide Transporter Activity
Peptide-transporting ATPase Activity
MHC Class Ib Protein Binding
MHC Class I Protein Binding
Peptide Antigen Binding
ATPase Activity, Coupled To Transmembrane Movement Of Substances
Protein Homodimerization Activity
ADP Binding
TAP1 Binding
TAP2 Binding
Biological Process
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Defense Response
Metabolic Process
Peptide Transport
Intracellular Transport Of Viral Protein In Host Cell
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Cytosol To ER Transport
Transmembrane Transport
Pathways
Class I MHC mediated antigen processing & presentation
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Antigen processing-Cross presentation
ER-Phagosome pathway
Adaptive Immune System
Drugs
Diseases
GWAS
Nephropathy (
21399633
)
Protein-Protein Interactions
107 interactors:
ADAMTSL4
ALPP
AQP1
ATG12
ATN1
BAHD1
BEX2
C10orf62
C19orf66
CATSPER1
CBX2
CCDC116
CCDC185
CCNK
CDC42EP1
CHCHD3
CHIC2
CLDN2
CNNM3
CNTFR
COL8A1
CRCT1
CREB5
CRY1
DBF4B
DLK2
EIF4E2
FAM107A
FAM27E3
FAM76B
FBXL18
FBXW5
GLRX3
GNE
GPATCH2L
GPRIN2
GRAP2
HHEX
HOXA1
HOXB9
IFI30
ILF3
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP26-1
KRTAP3-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2D
LCE3E
LCE4A
LINGO1
LNX1
MAPKBP1
MEOX2
MRPL4
NOTCH2NL
NPDC1
NUDT18
NUFIP2
OTX1
PCSK5
PDGFRB
PFKL
PHLDA1
PLSCR1
PLSCR4
PNKP
PRKAB2
PRR13
QPRT
RERE
RPS28
SLC25A10
SLC25A6
SMCP
SPATA3
SPG7
SPRY2
TAP1
TBC1D16
TBC1D23
TCEB3B
THAP10
THAP7
TOP3B
TXNDC5
ZBTB16
ZNF165
ZNF20
ZNF250
ZNF408
ZNF415
ZNF417
ZNF426
ZNF439
ZNF440
ZNF581
ZNF638
ZNF655
ZNF764
ZSCAN26
12 interactors:
ESR1
HLA-F
HLA-G
KRTAP4-12
MDFI
MUL1
PDIA3
PSMB5
PSMB8
TAP2
TAPBP
TDP2
Entrez ID
83755
6890
HPRD ID
13941
01359
Ensembl ID
ENSG00000213416
ENSG00000168394
Uniprot IDs
Q9BQ66
F5H648
Q03518
PDB IDs
1JJ7
Enriched GO Terms of Interacting Partners
?
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Biosynthetic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Keratinization
Anterior/posterior Pattern Specification
Regulation Of Cellular Process
Regulation Of Metabolic Process
Cellular Process
Keratinocyte Differentiation
Embryo Development
Phospholipid Scrambling
Metanephric Glomerulus Vasculature Development
Pattern Specification Process
Metanephric Glomerulus Development
Epidermal Cell Differentiation
Epidermis Development
Mitochondrion Organization
Metabolic Process
Forebrain Morphogenesis
Transcription From RNA Polymerase II Promoter
Glomerulus Vasculature Development
Multicellular Organismal Development
Organic Anion Transport
Inner Ear Development
Cell Migration Involved In Coronary Angiogenesis
Hepatic Duct Development
Abducens Nerve Formation
Metanephric Mesenchymal Cell Migration
Transepithelial Water Transport
Renin Secretion Into Blood Stream
Metanephric Descending Thin Limb Development
DGDP Catabolic Process
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Peptide Antigen
Antigen Processing And Presentation
Positive Regulation Of Signal Transduction
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I
Immune System Process
Antigen Processing And Presentation Of Endogenous Antigen
Type I Interferon Signaling Pathway
Cellular Response To Type I Interferon
Response To Type I Interferon
Response To Stress
Cellular Response To Stress
Signal Transduction
Negative Regulation Of Signal Transduction
Signaling
Negative Regulation Of Wnt Signaling Pathway
Positive Regulation Of Transferase Activity
Cell Communication
Negative Regulation Of Signaling
Activation Of JUN Kinase Activity
Response To Stimulus
Regulation Of Apoptotic Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Proteolysis
Cellular Response To Stimulus
Regulation Of Wnt Signaling Pathway
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Positive Regulation Of Catalytic Activity
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent
Regulation Of Cell Death
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of JUN Kinase Activity
Peptide Antigen Stabilization
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Protein Modification Process
Positive Regulation Of Ligase Activity
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of JUN Kinase Activity
Tagcloud
?
activates
acts
blocks
contain
crossover
crossovers
demonstrating
dominan
ecs
element
gamma
gas
hela
homodimers
ifn
isre
jak1
jaks
janus
p48
permits
phosphatase
shp
ss
stat1
stat1alpha
stat2
transporter
tyk
Tagcloud (Difference)
?
activates
acts
blocks
contain
crossover
crossovers
demonstrating
dominan
ecs
element
gamma
gas
hela
homodimers
ifn
isre
jak1
jaks
janus
p48
permits
phosphatase
shp
ss
stat1
stat1alpha
stat2
transporter
tyk
Tagcloud (Intersection)
?