ITCH and TP73

  • Number of citations of the paper that reports this interaction (PMID 15678106)
  • 69
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro, two hybrid, in vivo)

ITCH

TP73

Gene Name itchy E3 ubiquitin protein ligase tumor protein p73
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Visceral adipose tissue adjusted for BMI ( 22589738)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Visceral fat ( 22589738)
Protein-Protein Interactions 80 interactors: ARID1A ARRB2 ARRDC1 ARRDC3 ATN1 BECN1 CBL CBLC CDC34 CPSF6 CPSF7 CSNK2A1 CXCR4 CYLD DAZAP1 DTX1 DTX3L DVL2 ERBB4 EWSR1 FYN GNAI2 HNRNPL HNRNPUL1 JUN LAPTM5 LATS1 LITAF MAP2K4 MAPK8 MLANA N4BP1 NDFIP2 NEDD9 NFE2 NOTCH1 NUDT21 NUMB PABPC1 POLR2A POLR2B POLR2C POLR2E POU5F1 PRKACA RIPK1 RNF11 RPAP2 RPAP3 SCNN1A SCNN1B SF1 SGK3 SH3GL2 SMAD2 SMAD3 SMARCC1 SMARCC2 SMARCE1 SNX9 SPG20 STAM2 TP73 TRPC4 TRPV1 TRPV4 TXNIP UBAP2 UBAP2L UBC UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2G1 UBE2J2 UBE2K UBE2L3 URI1 WBP2 50 interactors: ABL1 AURKA BIN1 BUB1B CABLES1 CCNB1 CCND1 CCNE1 CDK1 CDK2 CEBPZ CHD3 CREBBP DAXX EP300 FBXO45 GNB2L1 HECW2 HIPK2 HIPK3 HMGB1 HRAS IKBKB ITCH KAT2B MAPK8 MDM2 MDM4 MYC NEDD4 NFYB PFDN5 PIAS1 PIN1 PML PPP1R13B RANBP9 RBX1 RCHY1 SMAD2 SMAD3 SUMO1 TDG TP53 TP63 UBE2I WT1 WWOX XPO1 YAP1
Entrez ID 83737 7161
HPRD ID 07565 03587
Ensembl ID ENSG00000078747 ENSG00000078900
Uniprot IDs Q96J02 C9J521 O15350
PDB IDs 2DMV 2KYK 2NQ3 2P4R 2YSF 3TUG 1COK 1DXS 2KBY 2WQI 2WQJ 2WTT 2XWC 3VD0 3VD1 3VD2 4A63 4G82 4G83 4GUQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ascertain  benzoin  biweekly  break  clearance  clinic  convenience  eradicating  erosions  ethanol  individual  irritation  ns  paint  pb  pe  penile  penis  podophyllin  regimens  resin  sequentially  superficial  supervised  tincture  treated  wart  warts  week 
acidic  amylin  calcitonin  calcr  causally  deltan  glycolysis  iapp  implement  interplay  isoforms  lymphomas  manipulating  p63  pramlintide  ramp3  reactivation  reprogramming  resemble  suppressive  ta  tap63  tap73  therapeutically  thymic  tp53  tp63  tumours 
Tagcloud (Difference) ?
ascertain  benzoin  biweekly  break  clearance  clinic  convenience  eradicating  erosions  ethanol  individual  irritation  ns  paint  pb  pe  penile  penis  podophyllin  regimens  resin  sequentially  superficial  supervised  tincture  treated  wart  warts  week 
acidic  amylin  calcitonin  calcr  causally  deltan  glycolysis  iapp  implement  interplay  isoforms  lymphomas  manipulating  p63  pramlintide  ramp3  reactivation  reprogramming  resemble  suppressive  ta  tap63  tap73  therapeutically  thymic  tp53  tp63  tumours 
Tagcloud (Intersection) ?