TP73 and RANBP9

Number of citations of the paper that reports this interaction (PMID 15558019)
20

Data Source:
BioGRID (pull down, affinity chromatography technology)

		TP73	RANBP9
Gene Name		tumor protein p73	RAN binding protein 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Factor Complex Golgi Apparatus Cytosol Cell Junction Intracellular Membrane-bounded Organelle	Nucleus Cytosol Microtubule Associated Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription P53 Binding Chromatin Binding Damaged DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Kinase Binding Identical Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	Protein Binding Ran GTPase Binding Enzyme Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Activation Of MAPK Activity Kidney Development Release Of Cytochrome C From Mitochondria Mismatch Repair Transcription From RNA Polymerase II Promoter Inflammatory Response Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Arrest Regulation Of Mitotic Cell Cycle Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Post-embryonic Development Response To X-ray Response To Organonitrogen Compound Response To Gamma Radiation Regulation Of Gene Expression Hippocampus Development Mitotic G1 DNA Damage Checkpoint Cerebrospinal Fluid Secretion Cellular Response To UV Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of JUN Kinase Activity Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Differentiation Positive Regulation Of Cell Size Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Digestive Tract Morphogenesis Neuron Development Positive Regulation Of Oligodendrocyte Differentiation Protein Tetramerization Negative Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator	Protein Complex Assembly Microtubule Nucleation Axon Guidance
Pathways			Axon guidance L1CAM interactions
Drugs
Diseases
GWAS		Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Visceral fat ( 22589738)	Breast cancer ( 23535729)
Protein-Protein Interactions		50 interactors: ABL1 AURKA BIN1 BUB1B CABLES1 CCNB1 CCND1 CCNE1 CDK1 CDK2 CEBPZ CHD3 CREBBP DAXX EP300 FBXO45 GNB2L1 HECW2 HIPK2 HIPK3 HMGB1 HRAS IKBKB ITCH KAT2B MAPK8 MDM2 MDM4 MYC NEDD4 NFYB PFDN5 PIAS1 PIN1 PML PPP1R13B RANBP9 RBX1 RCHY1 SMAD2 SMAD3 SUMO1 TDG TP53 TP63 UBE2I WT1 WWOX XPO1 YAP1	51 interactors: ADAP1 ADAP2 APC AR AXL BACE1 BRCA1 CACNA1G CALB1 CBS CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 OPRM1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1
Entrez ID		7161	10048
HPRD ID		03587	04835
Ensembl ID		ENSG00000078900	ENSG00000010017
Uniprot IDs		C9J521 O15350	Q96S59
PDB IDs		1COK 1DXS 2KBY 2WQI 2WQJ 2WTT 2XWC 3VD0 3VD1 3VD2 4A63 4G82 4G83 4GUQ
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Cycle Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cellular Protein Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Apoptotic Process Programmed Cell Death Negative Regulation Of Cell Cycle Cell Cycle Process Regulation Of Signal Transduction Cell Death Cellular Response To Stress Death Positive Regulation Of Gene Expression Regulation Of Protein Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Regulation Of Signaling Positive Regulation Of Protein Metabolic Process Viral Process Cellular Response To DNA Damage Stimulus Signal Transduction By P53 Class Mediator Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Response To Stress Mitotic Cell Cycle Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Death Cellular Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Proteolysis Negative Regulation Of Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process	Multicellular Organismal Development Anatomical Structure Development Developmental Process System Development Organ Development Response To Organic Substance Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell Communication Cellular Response To Organic Substance Signal Transduction Cellular Response To Organic Cyclic Compound Signaling DNA-templated Transcription, Initiation Cellular Response To Stimulus Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Metabolic Process Anatomical Structure Morphogenesis Response To Stimulus Response To Organic Cyclic Compound Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Tissue Development Response To Lipid Nervous System Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Steroid Hormone Mediated Signaling Pathway Response To Growth Factor Epithelium Development Wound Healing Negative Regulation Of Signal Transduction Regulation Of Cell Proliferation Response To Hormone Reproductive Process Regulation Of Intracellular Signal Transduction Apoptotic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Hormone-mediated Signaling Pathway Cell Activation Negative Regulation Of Signaling DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Tagcloud ?		acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 pramlintide ramp3 reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tumours	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Difference) ?		acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 pramlintide ramp3 reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tumours	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Intersection) ?