TP73 and MDM4

  • Number of citations of the paper that reports this interaction (PMID 11223036)
  • 21
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)
  • HPRD (in vitro)

TP73

MDM4

Gene Name tumor protein p73 MDM4, p53 regulator
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Visceral adipose tissue adjusted for BMI ( 22589738)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Visceral fat ( 22589738)
Protein-Protein Interactions 50 interactors: ABL1 AURKA BIN1 BUB1B CABLES1 CCNB1 CCND1 CCNE1 CDK1 CDK2 CEBPZ CHD3 CREBBP DAXX EP300 FBXO45 GNB2L1 HECW2 HIPK2 HIPK3 HMGB1 HRAS IKBKB ITCH KAT2B MAPK8 MDM2 MDM4 MYC NEDD4 NFYB PFDN5 PIAS1 PIN1 PML PPP1R13B RANBP9 RBX1 RCHY1 SMAD2 SMAD3 SUMO1 TDG TP53 TP63 UBE2I WT1 WWOX XPO1 YAP1 42 interactors: AKT1 APP ARF1 ATM CAPN7 CASP3 CD160 CDK1 CHEK1 CHEK2 CSNK1A1 E2F1 EP300 LRSAM1 MDM2 MKRN3 MNAT1 PRKAA1 RAD54B RB1 RN5S1@ RNF115 SFN SMAD3 SMAD4 SMARCA2 TP53 TP63 TP73 TRIM46 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 USP7 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID 7161 4194
HPRD ID 03587 04082
Ensembl ID ENSG00000078900 ENSG00000198625
Uniprot IDs C9J521 O15350 O15151 Q59FS6 Q68DC0
PDB IDs 1COK 1DXS 2KBY 2WQI 2WQJ 2WTT 2XWC 3VD0 3VD1 3VD2 4A63 4G82 4G83 4GUQ 2CR8 2VJE 2VJF 2VYR 3DAB 3EQY 3FDO 3FE7 3FEA 3JZO 3JZP 3JZQ 3LBJ 3U15
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acidic  amylin  calcitonin  calcr  causally  deltan  glycolysis  iapp  implement  interplay  isoforms  lymphomas  manipulating  p63  pramlintide  ramp3  reactivation  reprogramming  resemble  suppressive  ta  tap63  tap73  therapeutically  thymic  tp53  tp63  tumours 
aberrations  abstract  along  attractive  cdk  cdk4  checkpoint  correlate  cyclind  developments  entered  highlights  kinases  logical  make  maximizing  mdm2  melanoma  melanomagenesis  p16  preliminary  rb  rb1  reactivating  reactivation  reporting  summary  targeting  video 
Tagcloud (Difference) ?
acidic  amylin  calcitonin  calcr  causally  deltan  glycolysis  iapp  implement  interplay  isoforms  lymphomas  manipulating  p63  pramlintide  ramp3  reprogramming  resemble  suppressive  ta  tap63  tap73  therapeutically  thymic  tp53  tp63  tumours 
aberrations  abstract  along  attractive  cdk  cdk4  checkpoint  correlate  cyclind  developments  entered  highlights  kinases  logical  make  maximizing  mdm2  melanoma  melanomagenesis  p16  preliminary  rb  rb1  reactivating  reporting  summary  targeting  video 
Tagcloud (Intersection) ?
reactivation