ITCH and CXCR4

  • Number of citations of the paper that reports this interaction (PMID 19116316)
  • 22
  • Data Source:
  • BioGRID (pull down, biochemical, affinity chromatography technology)

ITCH

CXCR4

Gene Name itchy E3 ubiquitin protein ligase chemokine (C-X-C motif) receptor 4
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 80 interactors: ARID1A ARRB2 ARRDC1 ARRDC3 ATN1 BECN1 CBL CBLC CDC34 CPSF6 CPSF7 CSNK2A1 CXCR4 CYLD DAZAP1 DTX1 DTX3L DVL2 ERBB4 EWSR1 FYN GNAI2 HNRNPL HNRNPUL1 JUN LAPTM5 LATS1 LITAF MAP2K4 MAPK8 MLANA N4BP1 NDFIP2 NEDD9 NFE2 NOTCH1 NUDT21 NUMB PABPC1 POLR2A POLR2B POLR2C POLR2E POU5F1 PRKACA RIPK1 RNF11 RPAP2 RPAP3 SCNN1A SCNN1B SF1 SGK3 SH3GL2 SMAD2 SMAD3 SMARCC1 SMARCC2 SMARCE1 SNX9 SPG20 STAM2 TP73 TRPC4 TRPV1 TRPV4 TXNIP UBAP2 UBAP2L UBC UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2G1 UBE2J2 UBE2K UBE2L3 URI1 WBP2 32 interactors: ADRBK2 ARRB2 ATP13A2 CCR5 CD4 CTSG CXCL12 DPP4 ELANE GNA13 GNAI1 HLA-C HSPA8 ITCH JAK1 JAK2 JAK3 MYBL2 MYH9 PTK2 PTPN11 PTPN6 PTPRC SDC4 SOCS1 SOCS3 STAT1 STAT2 STAT3 STAT5B USP14 VAV1
Entrez ID 83737 7852
HPRD ID 07565 01217
Ensembl ID ENSG00000078747 ENSG00000121966
Uniprot IDs Q96J02 P61073
PDB IDs 2DMV 2KYK 2NQ3 2P4R 2YSF 3TUG 2K03 2K04 2K05 3ODU 3OE0 3OE6 3OE8 3OE9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ascertain  benzoin  biweekly  break  clearance  clinic  convenience  eradicating  erosions  ethanol  individual  irritation  ns  paint  pb  pe  penile  penis  podophyllin  regimens  resin  sequentially  superficial  supervised  tincture  treated  wart  warts  week 
capture  ccr1  ccr2  ccr5  ccr7  cd40  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded  responsiveness 
Tagcloud (Difference) ?
ascertain  benzoin  biweekly  break  clearance  clinic  convenience  eradicating  erosions  ethanol  individual  irritation  ns  paint  pb  pe  penile  penis  podophyllin  regimens  resin  sequentially  superficial  supervised  tincture  treated  wart  warts  week 
capture  ccr1  ccr2  ccr5  ccr7  cd40  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded  responsiveness 
Tagcloud (Intersection) ?