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CAPN1 and NDUFB7
Number of citations of the paper that reports this interaction (PubMedID
12358155
)
0
Data Source:
BioGRID
(two hybrid)
CAPN1
NDUFB7
Description
calpain 1
NADH:ubiquinone oxidoreductase subunit B7
Image
GO Annotations
Cellular Component
Cornified Envelope
Extracellular Region
Cytoplasm
Mitochondrion
Lysosome
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Extracellular Exosome
Calpain Complex
Ficolin-1-rich Granule Lumen
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Intermembrane Space
Membrane
Respiratory Chain Complex I
Molecular Function
Calcium-dependent Cysteine-type Endopeptidase Activity
Calcium Ion Binding
Protein Binding
Peptidase Activity
Cysteine-type Peptidase Activity
Hydrolase Activity
Metal Ion Binding
Protein Binding
NADH Dehydrogenase (ubiquinone) Activity
Biological Process
Proteolysis
Positive Regulation Of Cell Population Proliferation
Regulation Of Macroautophagy
Receptor Catabolic Process
Regulation Of Catalytic Activity
Mammary Gland Involution
Self Proteolysis
NMDA Selective Glutamate Receptor Signaling Pathway
Mitochondrial Electron Transport, NADH To Ubiquinone
Aerobic Respiration
Proton Motive Force-driven Mitochondrial ATP Synthesis
Proton Transmembrane Transport
Pathways
Degradation of the extracellular matrix
Degradation of the extracellular matrix
Neutrophil degranulation
Formation of the cornified envelope
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Respiratory electron transport
Complex I biogenesis
Drugs
4-[[(2S)-2-[[(2S)-3-Carboxy-2-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]butyl-(diaminomethylidene)azanium
N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]-L-leucinamide
(2S)-4-METHYL-2-(3-PHENYLTHIOUREIDO)-N-((3S)-TETRAHYDRO-2-HYDROXY-3-FURANYL)PENTANAMIDE
NADH
Diseases
GWAS
Urate levels (
31578528
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
Interacting Genes
55 interacting genes:
ACTC1
ACTN2
ARF6
ATG5
ATXN3
BCL2L1
BID
CAPNS1
CASP14
CAST
CBL
CDK5R1
CLEC4G
COL1A1
COL3A1
CREG1
CTSC
DES
ECHS1
F2R
F2RL1
FANCA
FANCG
FHL2
GNG12
GPT
GRIN2B
HNRNPD
IL1A
INPP4A
ITGB3
KCTD7
KNG1
LAMTOR1
MAPT
MYBPC3
NDUFB7
NFE2L1
NFKBIA
PRMT5
PSEN2
PTGDS
RAD21
SH3BGR
SLC22A1
SLIT3
SPTAN1
SPTBN1
STAT3
SYNE1
TINAGL1
TLE5
TP53
UFSP2
VIM
42 interacting genes:
AGBL2
AIRIM
ANKRD36B
ATG9A
CAPN1
CCDC24
CCNC
CDCA7L
CDKN2D
CHIC2
CINP
CKAP4
CTNNA3
DSCR9
ENKD1
FAM161B
FAM90A1
GEM
GPATCH2L
GYS1
KRTAP10-10
LMO2
MAGOHB
MAK
MEIS2
MKRN3
MLKL
NDUFB2
NFKBIB
NFKBID
RCOR3
RECK
RIPPLY1
RIPPLY2
SCNM1
SPRED2
STRA6
TLE5
ZNF330
ZNF417
ZNF564
ZNF587
Entrez ID
823
4713
HPRD ID
00253
11957
Ensembl ID
ENSG00000014216
ENSG00000099795
Uniprot IDs
B2RDI5
B4DWH5
P07384
P17568
PDB IDs
1ZCM
2ARY
7W7O
7X79
8GX3
5XTC
5XTD
5XTH
5XTI
Enriched GO Terms of Interacting Partners
?
Organelle Organization
Regulation Of Programmed Cell Death
Response To Alcohol
Regulation Of Organelle Organization
Regulation Of Apoptotic Process
Identical Protein Binding
Positive Regulation Of Organelle Organization
Regulation Of Multicellular Organismal Process
Protease Binding
Cytoplasm
Regulation Of Signal Transduction
Regulation Of Cellular Component Organization
Developmental Process
Regulation Of Cell Communication
Regulation Of Signaling
Cellular Response To Amino Acid Stimulus
Positive Regulation Of Gene Expression
Response To Lipid
Positive Regulation Of Programmed Cell Death
Negative Regulation Of MiRNA-mediated Gene Silencing
Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA
Negative Regulation Of Gene Expression
Regulation Of Intracellular Signal Transduction
Hepatocyte Apoptotic Process
Cytosol
Regulation Of Actin Filament Depolymerization
Negative Regulation Of Apoptotic Process
Cell Junction Maintenance
Regulation Of Renin Secretion Into Blood Stream
Regulation Of Autophagy
Sarcomere
Negative Regulation Of Programmed Cell Death
Regulation Of Actin Filament-based Process
Regulation Of Mitochondrial Membrane Permeability
G-protein Beta-subunit Binding
Regulation Of Protein Localization
Response To Amino Acid
Release Of Cytochrome C From Mitochondria
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Positive Regulation Of Signal Transduction
Response To Fluoride
Regulation Of Protein-containing Complex Disassembly
Positive Regulation Of Apoptotic Process
Cellular Component Maintenance
Regulation Of Membrane Permeability
Cysteine-type Peptidase Activity
Positive Regulation Of Cellular Component Organization
Regulation Of MiRNA-mediated Gene Silencing
Negative Regulation Of Protein Localization
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Tagcloud (Intersection)
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