NDUFB7 and ATG9A

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		NDUFB7	ATG9A
Name		NADH:ubiquinone oxidoreductase subunit B7	autophagy related 9A
Structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Respiratory Chain Complex I	Golgi Membrane Phagophore Assembly Site Autophagosome Membrane Cytoplasm Mitochondrion Endosome Late Endosome Autophagosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Membrane Cytoplasmic Vesicle Late Endosome Membrane Mitochondrial Membrane Phagophore Assembly Site Membrane Recycling Endosome Recycling Endosome Membrane Synaptic Membrane
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Protein Binding Phospholipid Scramblase Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Autophagosome Assembly Mitophagy Lipid Transport Autophagy Negative Regulation Of Macrophage Cytokine Production Plasma Membrane Phospholipid Scrambling Negative Regulation Of Interferon-beta Production Protein Localization To Golgi Apparatus Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Innate Immune Response Bone Morphogenesis Reticulophagy Programmed Necrotic Cell Death
Pathways		Respiratory electron transport Complex I biogenesis	Macroautophagy PINK1-PRKN Mediated Mitophagy
Drugs		NADH	None
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847 )	No GWAS studies recorded
Novel Interactors		None recorded	1 novel interactors: CHPF
Interacting Genes		42 interacting genes: AGBL2 AIRIM ANKRD36B ATG9A CAPN1 CCDC24 CCNC CDCA7L CDKN2D CHIC2 CINP CKAP4 CTNNA3 DSCR9 ENKD1 FAM161B FAM90A1 GEM GPATCH2L GYS1 KRTAP10-10 LMO2 MAGOHB MAK MEIS2 MKRN3 MLKL NDUFB2 NFKBIB NFKBID RCOR3 RECK RIPPLY1 RIPPLY2 SCNM1 SPRED2 STRA6 TLE5 ZNF330 ZNF417 ZNF564 ZNF587	48 interacting genes: ADAMTSL4 ANKRD10 AP2M1 CERCAM CFAP68 CIB4 CYSRT1 ETHE1 HDHD3 KLHL20 KPRP KRT31 KRT33B KRT34 KRT35 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP19-1 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP8-1 KRTAP9-2 LONRF1 MAPK6 MEOX1 MEOX2 MGAT5B NBPF19 NDUFB7 NOTCH2NLA OXER1 REL SRC SRCAP TBK1 TCF4 TRIM42 UBE3A YPEL3 ZBTB42 ZNF581 ZNF620
Entrez ID		4713	79065
HPRD ID		11957	07979
Ensembl ID		ENSG00000099795	ENSG00000198925
Uniprot IDs		P17568	Q7Z3C6
PDB IDs		5XTC 5XTD 5XTH 5XTI	6WQZ 6WR4 7JLO 7JLP 7JLQ 8KBZ 8KC3 8Y1L
GO Terms Enriched among Interactors		None	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Structural Molecule Activity Epidermis Development Intermediate Filament Organization Somite Specification Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process