CAPN1 and GPT

Number of citations of the paper that reports this interaction (PMID 12358155)
3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CAPN1	GPT
Gene Name		calpain 1, (mu/I) large subunit	glutamic-pyruvate transaminase (alanine aminotransferase)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Extracellular Vesicular Exosome	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding	L-alanine:2-oxoglutarate Aminotransferase Activity Pyridoxal Phosphate Binding
	Biological Process	Proteolysis Positive Regulation Of Cell Proliferation Extracellular Matrix Disassembly Extracellular Matrix Organization Receptor Catabolic Process	Cellular Amino Acid Biosynthetic Process Cellular Nitrogen Compound Metabolic Process L-alanine Catabolic Process Small Molecule Metabolic Process
Pathways		Degradation of the extracellular matrix	Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives
Drugs			Pyridoxal Phosphate L-Glutamic Acid L-Alanine Phenelzine
Diseases
GWAS
Protein-Protein Interactions		50 interactors: ACTC1 ACTN2 AES ARF6 BCL2L1 BID CAPNS1 CASP14 CAST CBL CDK5R1 CLEC4G COL1A1 COL3A1 CREG1 CTSC DES ECHS1 F2R F2RL1 FANCA FANCG FHL2 GNG12 GPT GRIN2B HNRNPD IL1A INPP4A ITGB3 KNG1 LAMTOR1 MYBPC3 NDUFB7 NFE2L1 NFKBIA PRMT5 PSEN2 PTGDS RAD21 SH3BGR SLIT3 SPTAN1 SPTBN1 STAT3 SYNE1 TINAGL1 TP53 UFSP2 VIM	2 interactors: CAPN1 CDC7
Entrez ID		823	2875
HPRD ID		00253	00689
Ensembl ID		ENSG00000014216	ENSG00000167701
Uniprot IDs		B2RDI5 B4DWH5 P07384	P24298
PDB IDs		1ZCM 2ARY
Enriched GO Terms of Interacting Partners?		Apoptotic Process Regulation Of Signal Transduction Programmed Cell Death Cell Death Death Movement Of Cell Or Subcellular Component Response To Stimulus Regulation Of Cell Death Regulation Of Signaling Muscle Filament Sliding Actin-myosin Filament Sliding Developmental Process Regulation Of Apoptotic Process Positive Regulation Of Signal Transduction Anatomical Structure Development Organ Development Response To Organic Substance Actin-mediated Cell Contraction Cell Differentiation Cell Development Protein Localization To Nucleus Protein Localization To Organelle System Development Enzyme Linked Receptor Protein Signaling Pathway Actin Filament-based Movement Multicellular Organismal Development Cell Surface Receptor Signaling Pathway Muscle Contraction Response To External Stimulus Anatomical Structure Morphogenesis Cellular Response To Stimulus Cell Activation Regulation Of Cellular Process Muscle System Process Axon Guidance Positive Regulation Of Transport Blood Coagulation Hemostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Localization Rhythmic Process Platelet Activation Wound Healing Negative Regulation Of Cell Death Positive Regulation Of Cell Death Regulation Of Protein Localization Regulation Of Cellular Component Organization Protein Import Into Nucleus Response To Stress	Double-strand Break Repair Via Break-induced Replication Positive Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Nuclear Cell Cycle DNA Replication Receptor Catabolic Process Positive Regulation Of Cell Proliferation Positive Regulation Of DNA-dependent DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle DNA Replication Initiation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of DNA Replication Receptor Metabolic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Extracellular Matrix Disassembly DNA-dependent DNA Replication Positive Regulation Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Regulation Of DNA Replication Positive Regulation Of DNA Metabolic Process Double-strand Break Repair G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Shape
Tagcloud ?		5k3 alpl armitage beadchip bovinesnp50 bull catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36	acth adrenocortical amphotericin anergy calcitriol candidiasis capsules clouding constellation electrocautery exclude gluconate got hypoparathyroidism manifest merieux microgram mucocutaneous multitest noninfectious occipital parathormone phpt pointing poliosis polyglandular transaminases truncal vitiligo
Tagcloud (Difference) ?		5k3 alpl armitage beadchip bovinesnp50 bull catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36	acth adrenocortical amphotericin anergy calcitriol candidiasis capsules clouding constellation electrocautery exclude gluconate got hypoparathyroidism manifest merieux microgram mucocutaneous multitest noninfectious occipital parathormone phpt pointing poliosis polyglandular transaminases truncal vitiligo
Tagcloud (Intersection) ?