CAPN1 and ECHS1

Number of citations of the paper that reports this interaction (PMID 22863883)
15

Data Source:
BioGRID (two hybrid, biochemical)
HPRD (two hybrid)

		CAPN1	ECHS1
Gene Name		calpain 1, (mu/I) large subunit	enoyl CoA hydratase, short chain, 1, mitochondrial
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Matrix Extracellular Vesicular Exosome
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding	Enoyl-CoA Hydratase Activity Protein Binding
	Biological Process	Proteolysis Positive Regulation Of Cell Proliferation Extracellular Matrix Disassembly Extracellular Matrix Organization Receptor Catabolic Process	Fatty Acid Beta-oxidation Cellular Lipid Metabolic Process Small Molecule Metabolic Process
Pathways		Degradation of the extracellular matrix	Fatty acid, triacylglycerol, and ketone body metabolism Beta oxidation of octanoyl-CoA to hexanoyl-CoA Metabolism of lipids and lipoproteins Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Mitochondrial Fatty Acid Beta-Oxidation Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA mitochondrial fatty acid beta-oxidation of saturated fatty acids Beta oxidation of hexanoyl-CoA to butanoyl-CoA Beta oxidation of butanoyl-CoA to acetyl-CoA
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: ACTC1 ACTN2 AES ARF6 BCL2L1 BID CAPNS1 CASP14 CAST CBL CDK5R1 CLEC4G COL1A1 COL3A1 CREG1 CTSC DES ECHS1 F2R F2RL1 FANCA FANCG FHL2 GNG12 GPT GRIN2B HNRNPD IL1A INPP4A ITGB3 KNG1 LAMTOR1 MYBPC3 NDUFB7 NFE2L1 NFKBIA PRMT5 PSEN2 PTGDS RAD21 SH3BGR SLIT3 SPTAN1 SPTBN1 STAT3 SYNE1 TINAGL1 TP53 UFSP2 VIM	8 interactors: CAPN1 CBWD2 CLDN12 CYP2E1 GRB2 PPM1B SERPINA1 UBA1
Entrez ID		823	1892
HPRD ID		00253	03799
Ensembl ID		ENSG00000014216	ENSG00000127884
Uniprot IDs		B2RDI5 B4DWH5 P07384	P30084
PDB IDs		1ZCM 2ARY	2HW5
Enriched GO Terms of Interacting Partners?		Apoptotic Process Regulation Of Signal Transduction Programmed Cell Death Cell Death Death Movement Of Cell Or Subcellular Component Response To Stimulus Regulation Of Cell Death Regulation Of Signaling Muscle Filament Sliding Actin-myosin Filament Sliding Developmental Process Regulation Of Apoptotic Process Positive Regulation Of Signal Transduction Anatomical Structure Development Organ Development Response To Organic Substance Actin-mediated Cell Contraction Cell Differentiation Cell Development Protein Localization To Nucleus Protein Localization To Organelle System Development Enzyme Linked Receptor Protein Signaling Pathway Actin Filament-based Movement Multicellular Organismal Development Cell Surface Receptor Signaling Pathway Muscle Contraction Response To External Stimulus Anatomical Structure Morphogenesis Cellular Response To Stimulus Cell Activation Regulation Of Cellular Process Muscle System Process Axon Guidance Positive Regulation Of Transport Blood Coagulation Hemostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Localization Rhythmic Process Platelet Activation Wound Healing Negative Regulation Of Cell Death Positive Regulation Of Cell Death Regulation Of Protein Localization Regulation Of Cellular Component Organization Protein Import Into Nucleus Response To Stress	Receptor Metabolic Process Response To Methanol
Tagcloud ?		5k3 alpl armitage beadchip bovinesnp50 bull catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36	1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Difference) ?		5k3 alpl armitage beadchip bull catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36	1n9c acsl3 agpat3 bta1 c10 c12 c14 c18 chuk dgat1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink prkg1 scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Intersection) ?		bovinesnp50