NDUFB7 and STRA6

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		NDUFB7	STRA6
Name		NADH:ubiquinone oxidoreductase subunit B7	signaling receptor and transporter of retinol STRA6
Structure			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Respiratory Chain Complex I	Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Protein Binding Retinal Binding Retinol Binding Retinol Transmembrane Transporter Activity Signaling Receptor Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Blood Vessel Development Kidney Development Pulmonary Valve Morphogenesis Ventricular Septum Development Heart Development Learning Feeding Behavior Lung Development Adrenal Gland Development Female Genitalia Development Retinol Transport Vocal Learning Camera-type Eye Development Ear Development Nose Morphogenesis Lung Alveolus Development Positive Regulation Of Behavior Digestive Tract Morphogenesis Embryonic Digestive Tract Development Developmental Growth Smooth Muscle Tissue Development Artery Morphogenesis Cognition Neuromuscular Process Head Development Head Morphogenesis Face Morphogenesis Lung Vasculature Development Diaphragm Development Embryonic Camera-type Eye Formation Eyelid Development In Camera-type Eye Uterus Morphogenesis Alveolar Primary Septum Development Pulmonary Artery Morphogenesis Paramesonephric Duct Development Vitamin A Import Into Cell Ductus Arteriosus Closure
Pathways		Respiratory electron transport Complex I biogenesis	The canonical retinoid cycle in rods (twilight vision) Defective visual phototransduction due to STRA6 loss of function
Drugs		NADH	None
Diseases		None	Anophthalmia and microphthalmia (A/M)
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847 )	Coffee consumption (cups per day) ( 31837886 ) Estimated glomerular filtration rate ( 31152163 ) Inhibitory control ( 29251981 ) Optic disc size ( 31809533 )
Interacting Genes		42 interacting genes: AGBL2 AIRIM ANKRD36B ATG9A CAPN1 CCDC24 CCNC CDCA7L CDKN2D CHIC2 CINP CKAP4 CTNNA3 DSCR9 ENKD1 FAM161B FAM90A1 GEM GPATCH2L GYS1 KRTAP10-10 LMO2 MAGOHB MAK MEIS2 MKRN3 MLKL NDUFB2 NFKBIB NFKBID RCOR3 RECK RIPPLY1 RIPPLY2 SCNM1 SPRED2 STRA6 TLE5 ZNF330 ZNF417 ZNF564 ZNF587	4 interacting genes: GLRX3 KRTAP10-6 KRTAP6-3 NDUFB7
Entrez ID		4713	64220
HPRD ID		11957	18122
Ensembl ID		ENSG00000099795	ENSG00000137868
Uniprot IDs		P17568	B3KPB8 Q9BX79
PDB IDs		5XTC 5XTD 5XTH 5XTI	Not available