NDUFB7 and MEIS2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		NDUFB7	MEIS2
Name		NADH:ubiquinone oxidoreductase subunit B7	Meis homeobox 2
Structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Respiratory Chain Complex I	Chromatin Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of DNA-templated Transcription Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Pathways		Respiratory electron transport Complex I biogenesis	None
Drugs		NADH	None
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847 )	Angiotensin-converting enzyme inhibitor intolerance ( 28030426 ) Hyperactive-impulsive symptoms ( 18821565 ) Intraocular pressure ( 24002674 ) Major depressive disorder ( 27479909 ) Post bronchodilator FEV1 in COPD ( 26634245 ) Postprandial triglyceride response ( 32603185 ) Response to antipsychotic treatment ( 20195266 ) Restless legs syndrome ( 29029846 ) Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 30584014 )
Interacting Genes		42 interacting genes: AGBL2 AIRIM ANKRD36B ATG9A CAPN1 CCDC24 CCNC CDCA7L CDKN2D CHIC2 CINP CKAP4 CTNNA3 DSCR9 ENKD1 FAM161B FAM90A1 GEM GPATCH2L GYS1 KRTAP10-10 LMO2 MAGOHB MAK MEIS2 MKRN3 MLKL NDUFB2 NFKBIB NFKBID RCOR3 RECK RIPPLY1 RIPPLY2 SCNM1 SPRED2 STRA6 TLE5 ZNF330 ZNF417 ZNF564 ZNF587	50 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 CARTPT CCDC196 CTAG1A CTAG1B DGCR6 DRD1 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SPMIP6 SQSTM1 TBX2 TIMM10B TLX1 TRIM25 TRIM42 VGLL1 ZNHIT3
Entrez ID		4713	4212
HPRD ID		11957	03443
Ensembl ID		ENSG00000099795	ENSG00000134138
Uniprot IDs		P17568	B3KPD8 B7Z6F6 O14770
PDB IDs		5XTC 5XTD 5XTH 5XTI	3K2A 4XRM 5BNG 5EG0
GO Terms Enriched among Interactors		None	Intermediate Filament Positive Regulation Of Long-term Synaptic Potentiation