CANX and CD82

Number of citations of the paper that reports this interaction (PMID 11350933)
8

Data Source:
HPRD (in vivo, in vitro)

		CANX	CD82
Gene Name		calnexin	CD82 molecule
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Smooth Endoplasmic Reticulum Rough Endoplasmic Reticulum Ribosome Membrane Axon Dendrite Cytoplasm Melanosome Neuronal Cell Body Dendritic Spine Protein Complex ER-mitochondrion Membrane Contact Site Extracellular Vesicular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Glycoprotein Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Apolipoprotein Binding Ionotropic Glutamate Receptor Binding Poly(A) RNA Binding Unfolded Protein Binding	Protein Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Folding Aging Protein Secretion Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process Synaptic Vesicle Endocytosis Chaperone-mediated Protein Folding Clathrin-mediated Endocytosis
Pathways		Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Antigen Presentation: Folding, assembly and peptide loading of class I MHC Virus Assembly and Release Defective MOGS causes MOGS-CDG (CDG-2b) Influenza Life Cycle Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation N-glycan trimming in the ER and Calnexin/Calreticulin cycle Assembly of Viral Components at the Budding Site Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Post-translational protein modification Defective ALG3 causes ALG3-CDG (CDG-1d) Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Influenza Infection Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Adaptive Immune System Calnexin/calreticulin cycle
Drugs		Antihemophilic Factor Tenecteplase
Diseases
GWAS			Hemostatic factors and hematological phenotypes ( 22443383)
Protein-Protein Interactions		42 interactors: ABCC2 APOB BCAP31 CD1D CD3D CD82 CFTR CSNK2A1 EBI3 EDEM1 F8 FAM107A FSHR GRIA1 GRIN1 HLA-A HTR3A IFNGR1 ITGA6 ITGB1 LCT LHCGR LPA LRP1 MBTPS1 MDM2 MTNR1A MTNR1B NDRG1 PDIA3 PLP1 PMP22 PRKCSH SERP1 SLC2A1 SLC4A1 SLC6A4 SMURF2 TF TG TRA TSHR	21 interactors: CANX CD19 CD4 CD63 EGFR ERBB2 ERBB3 HBEGF HLA-DMA HLA-DMB HLA-DRA IGSF8 ITGA3 ITGA4 ITGA6 ITGB1 ITGB2 LRP1 NUP88 PTGFRN VANGL1
Entrez ID		821	3732
HPRD ID		00252	09004
Ensembl ID		ENSG00000127022
Uniprot IDs		P27824	P27701
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Stimulus Cell Communication Cellular Response To Stimulus Signaling Signal Transduction Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Response To Organic Substance Response To Stress Regulation Of Cellular Process Immune System Process Cellular Ion Homeostasis Chemical Homeostasis System Development Cellular Homeostasis Regulation Of Signaling Cellular Chemical Homeostasis Response To External Stimulus Iodide Transport Positive Regulation Of Cell Adhesion Ion Homeostasis Sexual Reproduction Cholesterol Metabolic Process Synaptic Transmission Positive Regulation Of Cell-cell Adhesion Response To Abiotic Stimulus Homeostatic Process Sterol Metabolic Process Multicellular Organismal Development Cellular Cation Homeostasis Response To Organic Cyclic Compound Mating Anatomical Structure Development Cell-cell Signaling Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Cognition Regulation Of Establishment Of Protein Localization G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Activation Positive Regulation Of Nuclease Activity Rhythmic Process Response To Endoplasmic Reticulum Stress Organ Development Positive Regulation Of Metabolic Process Response To Light Stimulus Cell Adhesion Mediated By Integrin Reproductive Process Reproduction Negative Regulation Of Neuron Differentiation Regulation Of Protein Localization	Regulation Of Immune Response Immune System Process Regulation Of Immune System Process Positive Regulation Of Cell Adhesion Wound Healing Regulation Of Cell Adhesion Cell-matrix Adhesion Immune Response-regulating Signaling Pathway Response To Wounding Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Assembly Cell-substrate Adhesion Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Locomotion Integrin-mediated Signaling Pathway Immune Response Phosphatidylinositol-mediated Signaling Movement Of Cell Or Subcellular Component Single Organismal Cell-cell Adhesion Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway Cell Migration Cell Adhesion ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Developmental Process Cell Motility Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Cell-cell Adhesion Response To Fibroblast Growth Factor Response To Stress Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Neurotrophin TRK Receptor Signaling Pathway Heterotypic Cell-cell Adhesion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Cellular Extravasation Cell Activation Leukocyte Migration Neurotrophin Signaling Pathway Blood Coagulation Fc-epsilon Receptor Signaling Pathway Hemostasis Protein Localization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Multicellular Organismal Development
Tagcloud ?		5q35 boundary british centromeric conspicuously d5s2006 d5s2073 d5s408 dominantly fgfr4 genomewide hampered haplotypes hk3 hnrph1 lymphatic lymphedema milroy mim multipoint pcl penetrance positionally recombinants scorable segregated telomeric vicinity wiaf	additionally connexin32 contributes cx32 downregulated downregulation frequently hcc hepatocellular imply inhibiting invasion investigations kai1 metastasis negatively nude poor progresses promising rapidly recurrence repressed restoration suppress suppressor thereby upregulating vascular
Tagcloud (Difference) ?		5q35 boundary british centromeric conspicuously d5s2006 d5s2073 d5s408 dominantly fgfr4 genomewide hampered haplotypes hk3 hnrph1 lymphatic lymphedema milroy mim multipoint pcl penetrance positionally recombinants scorable segregated telomeric vicinity wiaf	additionally connexin32 contributes cx32 downregulated downregulation frequently hcc hepatocellular imply inhibiting invasion investigations kai1 metastasis negatively nude poor progresses promising rapidly recurrence repressed restoration suppress suppressor thereby upregulating vascular
Tagcloud (Intersection) ?