LUC7L2 and ATRX

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LUC7L2	ATRX
Gene Name		LUC7-like 2 (S. cerevisiae)	alpha thalassemia/mental retardation syndrome X-linked
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	U1 SnRNP Nuclear Speck	Nucleus Nucleoplasm Nuclear Heterochromatin PML Body Telomeric Heterochromatin SWI/SNF Superfamily-type Complex
	Molecular Function	MRNA Binding Protein Binding Enzyme Binding Poly(A) RNA Binding	DNA Binding DNA Helicase Activity Chromatin Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding DNA Translocase Activity Methylated Histone Binding Histone Binding Chromo Shadow Domain Binding
	Biological Process	MRNA Splice Site Selection	DNA Repair DNA Methylation DNA Recombination Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Spermatogenesis Positive Regulation Of Nuclear Cell Cycle DNA Replication DNA Damage Response, Signal Transduction By P53 Class Mediator Forebrain Development Replication Fork Processing Positive Regulation Of Telomere Maintenance DNA Duplex Unwinding Positive Regulation Of Transcription From RNA Polymerase II Promoter Sertoli Cell Development Seminiferous Tubule Development Cellular Response To Hydroxyurea Negative Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		54 interactors: AIMP2 ALB APP APPBP2 ATF7IP ATRX CADPS CCDC53 CDC37 CDK4 CDK5RAP2 CHD3 EXOC1 FAM173A FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG KIAA1377 KLHL20 LINC00341 LPL MAN2A2 MAP1LC3B NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRPK1 SRPK2 SRSF6 SRSF7 SSFA2 SVIL ULK2 UNC119 YWHAG ZCCHC10	21 interactors: ATN1 BLM CALM1 CCSER2 DAXX EZH2 HDAC1 HDAC4 HIST1H3A HIST2H3C KIAA1377 LUC7L2 NEK1 NSD1 PTN PTPN4 RAD51 SVIL WRN ZBED1 ZNF512B
Entrez ID		51631	546
HPRD ID		17456	02069
Ensembl ID		ENSG00000146963	ENSG00000085224
Uniprot IDs		Q9Y383	A4LAA3 B4DLW1 P46100
PDB IDs			2JM1 2LBM 2LD1 3QL9 3QLA 3QLC 3QLN
Enriched GO Terms of Interacting Partners?		Organelle Organization Establishment Of Localization In Cell Cellular Localization Protein Transport Regulation Of Kinase Activity Establishment Of Protein Localization Cell Cycle Process Anatomical Structure Development Intracellular Transport Cell Cycle Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Developmental Process Regulation Of Protein Kinase Activity Cellular Component Assembly Positive Regulation Of Cell Cycle Regulation Of MRNA Processing Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Development Regulation Of Cell Differentiation Multicellular Organismal Development Regulation Of RNA Splicing Exocytosis Regulation Of Protein Metabolic Process Regulation Of Neurogenesis Establishment Of Cell Polarity Protein Localization Chromatin Organization Retrograde Axon Cargo Transport Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Neuron Differentiation Nuclear Export Mitotic Cell Cycle Regulation Of Cell Size Apoptotic Process Axon Cargo Transport Programmed Cell Death Chromosome Organization Organelle Localization Regulation Of Cellular Process Regulation Of Cell Death Positive Regulation Of Mitotic Cell Cycle Phase Transition Cell Death Positive Regulation Of Metabolic Process Death Regulation Of Phosphorylation Positive Regulation Of Cell Cycle Phase Transition Regulation Of Protein Phosphorylation Regulation Of Gene Expression	Organelle Organization Chromosome Organization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Cellular Response To Camptothecin Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Conformation Change Negative Regulation Of Cellular Metabolic Process Response To Camptothecin Cellular Response To Radiation Response To Ionizing Radiation Negative Regulation Of Gene Expression Cellular Response To Ionizing Radiation Nucleobase-containing Compound Metabolic Process DNA Methylation Chromatin Organization Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Radiation DNA Duplex Unwinding DNA Geometric Change Response To Stress Cellular Nitrogen Compound Metabolic Process DNA Methylation On Cytosine DNA Modification Regulation Of Cell Division Chromatin Silencing At RDNA Replication Fork Processing Positive Regulation Of Protein Serine/threonine Kinase Activity Cell Cycle DNA-dependent DNA Replication Chromatin Modification Wound Healing Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cell Cycle Process Histone H4 Deacetylation DNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Response To Wounding Gene Expression Double-strand Break Repair Histone Modification
Tagcloud ?		add african alleles americans ankrd17 antihypertensive caucasian caucasians connections cox18 displaying diuretics elevations fto grin3a hctz heterozygotes hydrochlorothiazide hyperuricaemia padi4 pard3b pear pharmacogenomic replicated rs4784333 suggestive thiazide ua uric	12v2 altering banding beadchip bon constitution cytosnp exome frameshift gtg heterozygosity hiseq homozygous ilumina implicating indels lubrication muc neuroendocrine ngs nras ploidy pnet qgp sanger sequenced snvs stretches toolkit
Tagcloud (Difference) ?		add african alleles americans ankrd17 antihypertensive caucasian caucasians connections cox18 displaying diuretics elevations fto grin3a hctz heterozygotes hydrochlorothiazide hyperuricaemia padi4 pard3b pear pharmacogenomic replicated rs4784333 suggestive thiazide ua uric	12v2 altering banding beadchip bon constitution cytosnp exome frameshift gtg heterozygosity hiseq homozygous ilumina implicating indels lubrication muc neuroendocrine ngs nras ploidy pnet qgp sanger sequenced snvs stretches toolkit
Tagcloud (Intersection) ?