THAP7 and SET

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		THAP7	SET
Gene Name		THAP domain containing 7	SET nuclear proto-oncogene
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Metal Ion Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding	DNA Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Type 2A Regulator Activity Histone Binding
	Biological Process	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated	Mitotic Cell Cycle DNA Replication Nucleosome Assembly Nucleosome Disassembly Nucleocytoplasmic Transport Gene Expression Negative Regulation Of Histone Acetylation Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity
Pathways			Regulation of mRNA stability by proteins that bind AU-rich elements Mitotic Prophase Condensation of Prophase Chromosomes HuR stabilizes mRNA Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		34 interactors: APP CCDC85B CCNDBP1 EHMT2 GNAI1 GOLGA2 HCFC1 HDAC3 HIST1H3A HIST1H4A KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 LNX1 LURAP1 LZTS2 MAP1LC3B MDFI MID2 MTUS2 NOTCH2NL PELI2 PHC2 PIN1 PPP3CC SET TAF1B TFIP11 THAP11 TRAF1 TRAF2 ZDHHC17	51 interactors: ANP32A APEX1 APP CALM1 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 EP300 FAM111B FOS GZMA GZMK HDAC1 HIST1H2BA HIST1H3A HIST2H4A HIST3H3 HIST4H4 HMGB2 IRF1 JUNB KLF5 KMT2A MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PIK3CG PPP2CA PPP2R1B PRKAR1A PTMA RAC1 SDCBP SETBP1 SGOL1 TAF1A TERF1 TERF2 TERF2IP THAP7 TP53 TREX1 UCHL5
Entrez ID		80764	6418
HPRD ID		15500	09023
Ensembl ID		ENSG00000184436	ENSG00000119335
Uniprot IDs		Q9BT49	Q01105 Q5VXV3
PDB IDs			2E50
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Negative Regulation Of RNA Biosynthetic Process Cellular Component Assembly Chromatin Silencing At RDNA Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Silencing Protein Complex Assembly Regulation Of Transcription, DNA-templated Positive Regulation Of Intracellular Signal Transduction Regulation Of Nucleic Acid-templated Transcription Regulation Of Signal Transduction Regulation Of RNA Biosynthetic Process Protein-DNA Complex Assembly DNA Methylation Regulation Of RNA Metabolic Process DNA Replication-dependent Nucleosome Assembly Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Signal Transduction Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Regulation Of Signaling DNA Modification Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Gene Expression Chromatin Organization Regulation Of Nitrogen Compound Metabolic Process Regulation Of Binding Regulation Of Cellular Process Gene Silencing Nucleosome Assembly Positive Regulation Of NF-kappaB Transcription Factor Activity Chromatin Assembly Notch Signaling Pathway Nucleosome Organization Regulation Of MAPK Cascade Regulation Of Protein Binding Cellular Protein Modification Process Regulation Of Intracellular Signal Transduction Chromatin Assembly Or Disassembly Histone H3-K9 Modification Regulation Of JNK Cascade Chromosome Organization Histone Modification Spliceosomal Complex Disassembly	Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Metabolic Process Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Telomere Maintenance Developmental Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Apoptotic Process Programmed Cell Death Regulation Of Cell Cycle Process Cellular Metabolic Process DNA Replication-dependent Nucleosome Assembly Cell Cycle Transcription, DNA-templated Organelle Organization Regulation Of Gene Expression, Epigenetic Blood Coagulation Positive Regulation Of Protein Metabolic Process Chromatin Assembly RNA Biosynthetic Process Cellular Component Assembly Hemostasis Chromatin Organization Negative Regulation Of Cell Cycle Anatomical Structure Development Cellular Response To Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Body Fluid Levels Negative Regulation Of Transcription, DNA-templated Response To Growth Factor Negative Regulation Of Gene Expression
Tagcloud ?		15b belonging c2ch caenorhabditis chelator consensus coordinating cx dap4 defines e2f6 elegans evolutionarily histidine lin list orthologue phenanthroline proapoptotic repressor segregation similarities superfamily thap0 thap1 transposase uncharacterized zinc	already assessing cognition cognitive cogs computation correlating costs cps deterioration easy estimate exam global inasmuch mds meaningful mental mini minimum msd quite residents scale scales simple slightly straightforward substantially utility
Tagcloud (Difference) ?		15b belonging c2ch caenorhabditis chelator consensus coordinating cx dap4 defines e2f6 elegans evolutionarily histidine lin list orthologue phenanthroline proapoptotic repressor segregation similarities superfamily thap0 thap1 transposase uncharacterized zinc	already assessing cognition cognitive cogs computation correlating costs cps deterioration easy estimate exam global inasmuch mds meaningful mental mini minimum msd quite residents scale scales simple slightly straightforward substantially utility
Tagcloud (Intersection) ?