THAP7 and PPP3CC

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		THAP7	PPP3CC
Gene Name		THAP domain containing 7	protein phosphatase 3, catalytic subunit, gamma isozyme
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome Nuclear Speck	Cytosol Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Metal Ion Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding	Phosphoprotein Phosphatase Activity Calmodulin Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated	Apoptotic Process Dephosphorylation Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Activation of BAD and translocation to mitochondria Signaling by GPCR Opioid Signalling Programmed Cell Death DARPP-32 events Activation of BH3-only proteins Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS			HIV-1 control ( 20205591)
Protein-Protein Interactions		34 interactors: APP CCDC85B CCNDBP1 EHMT2 GNAI1 GOLGA2 HCFC1 HDAC3 HIST1H3A HIST1H4A KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 LNX1 LURAP1 LZTS2 MAP1LC3B MDFI MID2 MTUS2 NOTCH2NL PELI2 PHC2 PIN1 PPP3CC SET TAF1B TFIP11 THAP11 TRAF1 TRAF2 ZDHHC17	11 interactors: AMPH APP BCL2 BMPR1B CABIN1 CSNK2B HAX1 ITPKC SDC2 TGFBR1 THAP7
Entrez ID		80764	5533
HPRD ID		15500	00236
Ensembl ID		ENSG00000184436	ENSG00000120910
Uniprot IDs		Q9BT49	P48454
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Negative Regulation Of RNA Biosynthetic Process Cellular Component Assembly Chromatin Silencing At RDNA Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Silencing Protein Complex Assembly Regulation Of Transcription, DNA-templated Positive Regulation Of Intracellular Signal Transduction Regulation Of Nucleic Acid-templated Transcription Regulation Of Signal Transduction Regulation Of RNA Biosynthetic Process Protein-DNA Complex Assembly DNA Methylation Regulation Of RNA Metabolic Process DNA Replication-dependent Nucleosome Assembly Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Signal Transduction Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Regulation Of Signaling DNA Modification Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Gene Expression Chromatin Organization Regulation Of Nitrogen Compound Metabolic Process Regulation Of Binding Regulation Of Cellular Process Gene Silencing Nucleosome Assembly Positive Regulation Of NF-kappaB Transcription Factor Activity Chromatin Assembly Notch Signaling Pathway Nucleosome Organization Regulation Of MAPK Cascade Regulation Of Protein Binding Cellular Protein Modification Process Regulation Of Intracellular Signal Transduction Chromatin Assembly Or Disassembly Histone H3-K9 Modification Regulation Of JNK Cascade Chromosome Organization Histone Modification Spliceosomal Complex Disassembly	Cell Morphogenesis Involved In Differentiation Axonogenesis Cell Morphogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Differentiation Regulation Of Binding Neuron Projection Morphogenesis Neuron Projection Development Cell Projection Morphogenesis Axon Guidance Cell Part Morphogenesis Generation Of Neurons Regulation Of Cell Differentiation Regulation Of Protein Binding Neurogenesis Neuron Development Cell Development Regulation Of Protein Phosphorylation Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Projection Organization Chemotaxis Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Protein Metabolic Process Cell Surface Receptor Signaling Pathway Gonad Development Locomotion Positive Regulation Of Signal Transduction Development Of Primary Sexual Characteristics Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Phosphorylation Negative Regulation Of Cell Proliferation Protein Phosphorylation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Response To Wounding Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Phosphorylation Nervous System Development Developmental Growth Sex Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Neuron Apoptotic Process Thymus Development Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Sexual Reproduction
Tagcloud ?		15b belonging c2ch caenorhabditis chelator consensus coordinating cx dap4 defines e2f6 elegans evolutionarily histidine lin list orthologue phenanthroline proapoptotic repressor segregation similarities superfamily thap0 thap1 transposase uncharacterized zinc	ankk1 ankyrin catechol comt contradicting disabilities drd2 economical google htt industrialized isozyme keywords kibra lifelong nefh neurofilament neurotrophic nos3 penetrating repercussions researches return roughly scholar slc6a4 solute tbi traumatic
Tagcloud (Difference) ?		15b belonging c2ch caenorhabditis chelator consensus coordinating cx dap4 defines e2f6 elegans evolutionarily histidine lin list orthologue phenanthroline proapoptotic repressor segregation similarities superfamily thap0 thap1 transposase uncharacterized zinc	ankk1 ankyrin catechol comt contradicting disabilities drd2 economical google htt industrialized isozyme keywords kibra lifelong nefh neurofilament neurotrophic nos3 penetrating repercussions researches return roughly scholar slc6a4 solute tbi traumatic
Tagcloud (Intersection) ?