SET and TAF1A

Number of citations of the paper that reports this interaction (PubMedID 11163245)
0

Data Source:
BioGRID (biochemical, pull down)
HPRD (in vitro, in vivo)

		SET	TAF1A
Description		SET nuclear proto-oncogene	TATA-box binding protein associated factor, RNA polymerase I subunit A
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm	RNA Polymerase I Transcription Regulator Complex Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Microtubule Cytoskeleton
	Molecular Function	DNA Binding Chromatin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity Histone Binding	DNA Binding Protein Binding
	Biological Process	DNA Replication Nucleosome Assembly Nucleosome Disassembly Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of DNA-templated Transcription	Transcription By RNA Polymerase I Transcription By RNA Polymerase II
Pathways		Condensation of Prophase Chromosomes HuR (ELAVL1) binds and stabilizes mRNA	SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457)	Trunk fat mass ( 28552196)
Interacting Genes		69 interacting genes: ANP32A APEX1 APP CALM1 CDCA8 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 ENO1 EP300 ESR1 FAM111B FBXO7 FOS FOXO1 GZMA GZMK H1-1 H2BC1 H3-3A H3-4 H4C14 H4C16 HMGB2 IRF1 JUNB KLF5 KMT2A LGMN MDM2 MEOX2 MTERF1 NEDD8 NME1 NUCB1 NUPR1 PAX6 PIK3CG PPP2CA PPP2R1B PRKAR1A PTEN PTMA RAC1 SDCBP SETBP1 SGO1 SGO2 TAF1A TERF1 TERF2 TERF2IP TEX35 THAP7 TLE5 TREX1 TRIM55 TRIM63 UBE3A UCHL5 XRCC6 ZNF17 ZNF438 ZNF85	20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4C1 H4C16 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF
Entrez ID		6418	9015
HPRD ID		09023	05362
Ensembl ID		ENSG00000119335	ENSG00000143498
Uniprot IDs		A0A8J8YYJ1 Q01105 Q5VXV3	A8K4K5 B4DS21 Q15573
PDB IDs		2E50 7MTO
Enriched GO Terms of Interacting Partners?		Nucleus DNA Binding Chromosome Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Negative Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Telomere Organization Chromosome, Telomeric Region Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Chromatin Organization Regulation Of Multicellular Organismal Process Chromatin Remodeling Regulation Of Gene Expression Regulation Of Phosphorus Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Nucleosome Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of ATP Metabolic Process Double-stranded Telomeric DNA Binding Nuclear Telomere Cap Complex Regulation Of Purine Nucleotide Metabolic Process Nucleosome Organization Regulation Of Developmental Process Protein-DNA Complex Assembly Regulation Of Glycolytic Process Regulation Of Cell Cycle Regulation Of Carbohydrate Catabolic Process Protein-containing Complex Negative Regulation Of RNA Metabolic Process Regulation Of Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Chromatin Regulation Of Programmed Cell Death Protein-DNA Complex Double-stranded DNA Binding Intracellular Signal Transduction Positive Regulation Of Macromolecule Metabolic Process	Protein-DNA Complex Assembly Protein-containing Complex Assembly RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Transcription Preinitiation Complex Assembly Protein-containing Complex Organization Transcription Initiation At RNA Polymerase I Promoter DNA Binding DNA-templated Transcription Initiation Nucleoplasm Structural Constituent Of Chromatin Chromatin Remodeling Cellular Component Assembly Nucleosome Assembly Protein Heterodimerization Activity Transcription By RNA Polymerase I Nucleosome Nucleosome Organization Chromatin Organization DNA-templated Transcription RNA Polymerase Transcription Factor SL1 Complex RNA Polymerase I General Transcription Initiation Factor Activity Nucleus Macromolecule Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process Regulation Of DNA-templated Transcription Initiation RRNA Transcription TBP-class Protein Binding Nucleic Acid Metabolic Process RNA Polymerase I Transcription Regulator Complex TFIIB-class Transcription Factor Binding Chromosome Fibroblast Proliferation Protein-containing Complex RNA Polymerase II Preinitiation Complex Assembly Protein Localization To Chromatin Nucleobase-containing Compound Metabolic Process MRNA Transcription Positive Regulation Of Transcription Initiation By RNA Polymerase II Nucleolus Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Chromatin Binding Core Promoter Sequence-specific DNA Binding CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Protein Localization To Chromosome Stem Cell Differentiation
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