SET and ELF4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SET	ELF4
Gene Name		SET nuclear proto-oncogene	E74-like factor 4 (ets domain transcription factor)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Protein Complex Perinuclear Region Of Cytoplasm	Nucleoplasm PML Body
	Molecular Function	DNA Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Type 2A Regulator Activity Histone Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Binding
	Biological Process	Mitotic Cell Cycle DNA Replication Nucleosome Assembly Nucleosome Disassembly Nucleocytoplasmic Transport Gene Expression Negative Regulation Of Histone Acetylation Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity	Natural Killer Cell Proliferation NK T Cell Proliferation Transcription From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements Mitotic Prophase Condensation of Prophase Chromosomes HuR stabilizes mRNA Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		51 interactors: ANP32A APEX1 APP CALM1 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 EP300 FAM111B FOS GZMA GZMK HDAC1 HIST1H2BA HIST1H3A HIST2H4A HIST3H3 HIST4H4 HMGB2 IRF1 JUNB KLF5 KMT2A MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PIK3CG PPP2CA PPP2R1B PRKAR1A PTMA RAC1 SDCBP SETBP1 SGOL1 TAF1A TERF1 TERF2 TERF2IP THAP7 TP53 TREX1 UCHL5	9 interactors: CASP4 FBXO4 FBXO7 NPM1 PML RUNX1 SET SKP2 UBB
Entrez ID		6418	2000
HPRD ID		09023	06499
Ensembl ID		ENSG00000119335	ENSG00000102034
Uniprot IDs		Q01105 Q5VXV3	Q99607
PDB IDs		2E50
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Metabolic Process Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Telomere Maintenance Developmental Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Apoptotic Process Programmed Cell Death Regulation Of Cell Cycle Process Cellular Metabolic Process DNA Replication-dependent Nucleosome Assembly Cell Cycle Transcription, DNA-templated Organelle Organization Regulation Of Gene Expression, Epigenetic Blood Coagulation Positive Regulation Of Protein Metabolic Process Chromatin Assembly RNA Biosynthetic Process Cellular Component Assembly Hemostasis Chromatin Organization Negative Regulation Of Cell Cycle Anatomical Structure Development Cellular Response To Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Body Fluid Levels Negative Regulation Of Transcription, DNA-templated Response To Growth Factor Negative Regulation Of Gene Expression	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of Transferase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Proteolysis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Macromolecule Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Cellular Response To Transforming Growth Factor Beta Stimulus Protein Ubiquitination Regulation Of Protein Metabolic Process Response To Transforming Growth Factor Beta Protein Modification By Small Protein Conjugation Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cytoplasmic Transport Regulation Of Apoptotic Process Mitotic Cell Cycle Nucleocytoplasmic Transport Intracellular Transport Nuclear Transport Regulation Of Cell Death DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Cell Aging Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest
Tagcloud ?		already assessing cognition cognitive cogs computation correlating costs cps deterioration easy estimate exam global inasmuch mds meaningful mental mini minimum msd quite residents scale scales simple slightly straightforward substantially utility	6h arabidopsis arrythmo circadian clock compromised cop1 cycles dark darkness diel elf3 elip1 example flowering influenced light lux night periods photomorphogenic plants prr9 pseudo seedlings sensing subjective uv uvr8
Tagcloud (Difference) ?		already assessing cognition cognitive cogs computation correlating costs cps deterioration easy estimate exam global inasmuch mds meaningful mental mini minimum msd quite residents scale scales simple slightly straightforward substantially utility	6h arabidopsis arrythmo circadian clock compromised cop1 cycles dark darkness diel elf3 elip1 example flowering influenced light lux night periods photomorphogenic plants prr9 pseudo seedlings sensing subjective uv uvr8
Tagcloud (Intersection) ?