SET and ANP32A

Number of citations of the paper that reports this interaction (PMID 11163245)
114

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		SET	ANP32A
Gene Name		SET nuclear proto-oncogene	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Protein Complex Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Type 2A Regulator Activity Histone Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Mitotic Cell Cycle DNA Replication Nucleosome Assembly Nucleosome Disassembly Nucleocytoplasmic Transport Gene Expression Negative Regulation Of Histone Acetylation Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nucleocytoplasmic Transport Gene Expression Intracellular Signal Transduction
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements Mitotic Prophase Condensation of Prophase Chromosomes HuR stabilizes mRNA Cell Cycle, Mitotic M Phase	Regulation of mRNA stability by proteins that bind AU-rich elements HuR stabilizes mRNA
Drugs
Diseases
GWAS		Eating disorders (purging via substances) ( 23568457)	Esophageal cancer ( 21642993)
Protein-Protein Interactions		51 interactors: ANP32A APEX1 APP CALM1 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 EP300 FAM111B FOS GZMA GZMK HDAC1 HIST1H2BA HIST1H3A HIST2H4A HIST3H3 HIST4H4 HMGB2 IRF1 JUNB KLF5 KMT2A MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PIK3CG PPP2CA PPP2R1B PRKAR1A PTMA RAC1 SDCBP SETBP1 SGOL1 TAF1A TERF1 TERF2 TERF2IP THAP7 TP53 TREX1 UCHL5	27 interactors: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE HIST3H3 HIST4H4 HSPB3 KPNA1 KPNA5 KPNA6 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1
Entrez ID		6418	8125
HPRD ID		09023	09014
Ensembl ID		ENSG00000119335	ENSG00000140350
Uniprot IDs		Q01105 Q5VXV3	P39687
PDB IDs		2E50	2JE0 2JE1
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Metabolic Process Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Telomere Maintenance Developmental Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Apoptotic Process Programmed Cell Death Regulation Of Cell Cycle Process Cellular Metabolic Process DNA Replication-dependent Nucleosome Assembly Cell Cycle Transcription, DNA-templated Organelle Organization Regulation Of Gene Expression, Epigenetic Blood Coagulation Positive Regulation Of Protein Metabolic Process Chromatin Assembly RNA Biosynthetic Process Cellular Component Assembly Hemostasis Chromatin Organization Negative Regulation Of Cell Cycle Anatomical Structure Development Cellular Response To Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Body Fluid Levels Negative Regulation Of Transcription, DNA-templated Response To Growth Factor Negative Regulation Of Gene Expression	DNA Replication-dependent Nucleosome Assembly Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Silencing At RDNA Nucleosome Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromatin Assembly Negative Regulation Of Transcription, DNA-templated Nucleocytoplasmic Transport Nuclear Transport Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Chromatin Silencing Negative Regulation Of Cellular Metabolic Process DNA Methylation On Cytosine Cytoplasmic Transport DNA Conformation Change Gene Expression DNA Metabolic Process Negative Regulation Of Gene Expression, Epigenetic NLS-bearing Protein Import Into Nucleus Telomere Maintenance Regulation Of Nitrogen Compound Metabolic Process DNA Modification Regulation Of Gene Expression, Epigenetic Nucleobase-containing Compound Metabolic Process Cellular Macromolecular Complex Assembly Gene Silencing Regulation Of Metabolic Process Histone H4-K20 Demethylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Regulation Of RNA Metabolic Process Intracellular Transport Protein Localization To Nucleus DNA Methylation Nitrogen Compound Metabolic Process Demethylation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Organelle Organization
Tagcloud ?		already assessing cognition cognitive cogs computation correlating costs cps deterioration easy estimate exam global inasmuch mds meaningful mental mini minimum msd quite residents scale scales simple slightly straightforward substantially utility	achn brdu capg capping chd4 chromodomain coded constrast cyclind1 helicase icpl illustrated isotope judged lentivirus lysates miapaca2 p53wt pp32 pp32r1 pp32r1y140h proteome r248w reside reverted shuttling transduced untransduced
Tagcloud (Difference) ?		already assessing cognition cognitive cogs computation correlating costs cps deterioration easy estimate exam global inasmuch mds meaningful mental mini minimum msd quite residents scale scales simple slightly straightforward substantially utility	achn brdu capg capping chd4 chromodomain coded constrast cyclind1 helicase icpl illustrated isotope judged lentivirus lysates miapaca2 p53wt pp32 pp32r1 pp32r1y140h proteome r248w reside reverted shuttling transduced untransduced
Tagcloud (Intersection) ?