HAUS1 and MED4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HAUS1	MED4
Gene Name		HAUS augmin-like complex, subunit 1	mediator complex subunit 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Microtubule HAUS Complex	Nucleus Nucleoplasm Membrane Mediator Complex
	Molecular Function	Molecular_function Protein Binding	RNA Polymerase II Transcription Cofactor Activity Transcription Cofactor Activity Receptor Activity Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Mitotic Nuclear Division Spindle Assembly Centrosome Organization Cell Division	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		66 interactors: AK8 ARFIP2 BLOC1S6 C3orf62 CAGE1 CCDC114 CCDC136 CCDC53 CCDC57 CCHCR1 CDR2 CEP170P1 CEP44 CEP55 CEP57L1 CEP63 CEP70 DCTN2 DMD DTNBP1 FGFR1OP2 GOLGA2 IFIT3 IFT20 INCA1 KDM1A KIFC3 KRT15 KRT18 KRT19 KRT31 KRT38 KRT40 KXD1 LDOC1 LURAP1 MAD1L1 MAGEA6 MCM10 MCM3 MED4 MED7 MIPOL1 MTUS2 NDC80 NECAB2 NINL NUP54 NUP62 PDE4DIP SPAG5 SPERT STX11 SYCE1 SYCE3 TFIP11 TFPT TRAF1 TRIM23 TRIM27 TRIM54 TRIM69 TSG101 USHBP1 VPS52 ZNF471	36 interactors: AES AMOT AP2M1 ATF7IP C1orf216 CCDC101 CCDC146 CCHCR1 CTDP1 CTNNBL1 FAM13C FOXJ3 FRMD6 FTCD HAUS1 IFT20 KIFC3 LRRFIP1 MAB21L3 MCRS1 MED13 MED25 MED30 MED9 NDC80 NDE1 PCBD2 PUM2 SDCBP SMARCD1 SMARCE1 SSX3 TNFAIP8 TXLNA USHBP1 WDTC1
Entrez ID		115106	29079
HPRD ID		16385	16145
Ensembl ID		ENSG00000152240	ENSG00000136146
Uniprot IDs		Q96CS2	Q9NPJ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Cell Cycle Process Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Division Microtubule-based Process Cytoskeleton Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Organelle Localization Protein Localization G2/M Transition Of Mitotic Cell Cycle Spindle Organization Establishment Of Protein Localization Cellular Pigmentation Cellular Localization Mitotic Nuclear Division Establishment Of Organelle Localization Protein Transport Anterograde Synaptic Vesicle Transport Establishment Of Localization In Cell Establishment Of Vesicle Localization Post-Golgi Vesicle-mediated Transport Vesicle Organization Viral Process Melanosome Organization Vesicle Localization Pigment Granule Organization Intracellular Transport Synaptonemal Complex Assembly Synaptonemal Complex Organization Chromosome Segregation Anterograde Axon Cargo Transport Synaptic Vesicle Transport Cellular Component Assembly Pigmentation Membrane Organization Microtubule Cytoskeleton Organization Endomembrane System Organization Actin Filament-based Process Spliceosomal Complex Disassembly Regulation Of Primitive Erythrocyte Differentiation Regulation Of Metaphase Plate Congression Golgi To Plasma Membrane CFTR Protein Transport Opsin Transport Melanosome Transport Mitotic Nuclear Envelope Disassembly Regulation Of Organelle Organization Microtubule-based Transport	Organelle Organization Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Process Regulation Of Nitrogen Compound Metabolic Process Gene Expression Nucleosome Disassembly Cellular Protein Localization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Establishment Of Cell Polarity Cellular Localization Cellular Nitrogen Compound Metabolic Process Mitotic Nuclear Division Centrosome Localization Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Establishment Of Mitotic Spindle Orientation Androgen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Mediator Complex Assembly Opsin Transport Regulation Of Cellular Process Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Nitrogen Compound Metabolic Process Chromosome Organization Establishment Or Maintenance Of Cell Polarity Chromatin Organization Cell Division Protein Localization Negative Regulation Of Transcription, DNA-templated Movement Of Cell Or Subcellular Component Spindle Localization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Microtubule-based Process Pteridine-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cytoskeleton Organization Negative Regulation Of RNA Biosynthetic Process
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