HAUS1 and SSC5D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HAUS1	SSC5D
Description		HAUS augmin like complex subunit 1	scavenger receptor cysteine rich family member with 5 domains
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule HAUS Complex Mitotic Spindle Microtubule	Extracellular Region Extracellular Space Cytoplasm Membrane Extracellular Matrix
	Molecular Function	Protein Binding	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding
	Biological Process	Centrosome Cycle Regulation Of Microtubule Nucleation Spindle Assembly Cell Division	Immune System Process Defense Response Vesicle-mediated Transport Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-8 Production Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Scavenging by Class B Receptors
Drugs
Diseases
GWAS			Height ( 28552196) Lung adenocarcinoma ( 28604730)
Interacting Genes		82 interacting genes: AK8 ARFIP2 ATP6V1D BFSP2 BLOC1S6 BORCS6 C3orf62 CAGE1 CBY2 CCDC136 CCDC57 CCHCR1 CDR2 CENPP CEP170P1 CEP44 CEP55 CEP57L1 CEP63 CEP70 DCTN2 DMD DTNBP1 FAM161B FGFR1OP2 GOLGA2 HGS HOOK2 IFIT3 IFT20 INCA1 KDM1A KIFC3 KRT1 KRT15 KRT18 KRT19 KRT3 KRT31 KRT38 KRT40 KXD1 LDOC1 LURAP1 MAD1L1 MAGEA6 MCM10 MCM3 MED4 MED7 MIPOL1 MTUS2 NDC80 NECAB2 NINL NUP54 NUP62 ODAD1 PDE4DIP PIBF1 PKN1 POLR3C SPAG5 SSC5D STX11 SYCE1 SYCE3 TEAD4 TFIP11 TFPT TRAF1 TRIM23 TRIM27 TRIM54 TRIM69 TSG101 TXN2 USHBP1 VPS37C VPS52 WASHC3 ZNF471	17 interacting genes: BLOC1S2 CEP170P1 DTNBP1 EXOC7 HAUS1 KRT27 MED11 MED21 MED29 NECAB2 NUP62 PIN1 SDCBP SEC23IP SKA1 TCEA2 TRAF1
Entrez ID		115106	284297
HPRD ID		16385	11444
Ensembl ID		ENSG00000152240	ENSG00000179954
Uniprot IDs		Q96CS2	A1L4H1
PDB IDs		7SQK
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organelle Organization Centrosome Microtubule-based Process Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Cytoskeleton Organization Intermediate Filament Organization Protein Binding Structural Constituent Of Skin Epidermis Keratin Filament Organelle Assembly Intermediate Filament Identical Protein Binding Microtubule Organizing Center Organization Establishment Of Localization In Cell Supramolecular Fiber Organization Organelle Localization Intracellular Transport Centrosome Cycle Microtubule Binding Intracellular Protein Localization Protein Localization To Centrosome Metaphase Chromosome Alignment Cellular Component Assembly Protein Transport Cilium Organization Centriole Assembly Spindle Organization Cellular Localization Structural Molecule Activity Establishment Of Protein Localization Cilium Assembly Microtubule Establishment Of Organelle Localization Chromosome Localization BLOC-1 Complex Plasma Membrane Bounded Cell Projection Assembly Microtubule Cytoskeleton Organization Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Projection Assembly Mitotic Metaphase Chromosome Alignment Protein Localization To Cytoskeleton Spindle Pole Structural Constituent Of Cytoskeleton Vesicle Organization Centriole Centriole Replication Protein Localization To Organelle Endosomal Transport	Regulation Of DNA-templated Transcription Elongation Core Mediator Complex Cytoskeleton Organization Cellular Component Assembly RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Mediator Complex Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Receptor Internalization Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Mitotic Cytokinesis Organelle Localization Regulation Of Cytokinesis Microtubule-based Process Regulation Of Mitotic Cytokinesis BLOC-1 Complex Negative Regulation Of Receptor Internalization Regulation Of Transcription Elongation By RNA Polymerase II Mitotic Spindle Microtubule Anterograde Synaptic Vesicle Transport Regulation Of Mitotic Nuclear Division Regulation Of Receptor-mediated Endocytosis Organelle Organization Transcription Coregulator Activity Platelet Dense Granule Organization Centrosome Regulation Of Nuclear Division Negative Regulation Of Receptor-mediated Endocytosis Flemming Body Regulation Of Microtubule Cytoskeleton Organization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Regulation Of Cell Division Midbody Protein-DNA Complex Assembly Positive Regulation Of Cytokinesis Microtubule Cytoskeleton Organization Anterograde Axonal Transport Cis-trans Isomerase Activity Interleukin-5 Receptor Complex Positive Regulation Of Mitotic Nuclear Division Mitotic Metaphase Chromosome Alignment Vesicle Transport Along Microtubule Establishment Of Protein Localization
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