HAUS1 and KXD1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		HAUS1	KXD1
Description		HAUS augmin like complex subunit 1	KxDL motif containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule HAUS Complex Mitotic Spindle Microtubule	Lysosome Lysosomal Membrane Membrane BLOC-1 Complex Cytoplasmic Side Of Lysosomal Membrane BORC Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Centrosome Cycle Regulation Of Microtubule Nucleation Spindle Assembly Cell Division	Vesicle-mediated Transport Lysosome Localization Regulation Of Endosome Size Regulation Of Lysosome Size Organelle Transport Along Microtubule
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes		82 interacting genes: AK8 ARFIP2 ATP6V1D BFSP2 BLOC1S6 BORCS6 C3orf62 CAGE1 CBY2 CCDC136 CCDC57 CCHCR1 CDR2 CENPP CEP170P1 CEP44 CEP55 CEP57L1 CEP63 CEP70 DCTN2 DMD DTNBP1 FAM161B FGFR1OP2 GOLGA2 HGS HOOK2 IFIT3 IFT20 INCA1 KDM1A KIFC3 KRT1 KRT15 KRT18 KRT19 KRT3 KRT31 KRT38 KRT40 KXD1 LDOC1 LURAP1 MAD1L1 MAGEA6 MCM10 MCM3 MED4 MED7 MIPOL1 MTUS2 NDC80 NECAB2 NINL NUP54 NUP62 ODAD1 PDE4DIP PIBF1 PKN1 POLR3C SPAG5 SSC5D STX11 SYCE1 SYCE3 TEAD4 TFIP11 TFPT TRAF1 TRIM23 TRIM27 TRIM54 TRIM69 TSG101 TXN2 USHBP1 VPS37C VPS52 WASHC3 ZNF471	42 interacting genes: APPL1 ARHGDIG C4orf46 CCDC185 CCDC33 CEP170P1 CEP19 CEP63 DYRK2 ELOA ELOA2 EWSR1 EXOC7 FXR2 GABARAPL1 HAUS1 IFT20 ING5 ITSN2 KRT81 LMO3 LNX1 LRRC45 MAB21L3 MAP1LC3A MAP1LC3B MCRS1 MOB1A MYH7 NIF3L1 NUDT18 RABGEF1 RNF183 RPL9 STX11 TCEA2 TPM1 TPM3 UTP6 ZBTB25 ZC4H2 ZNF417
Entrez ID		115106	79036
HPRD ID		16385	14526
Ensembl ID		ENSG00000152240	ENSG00000105700
Uniprot IDs		Q96CS2	Q9BQD3
PDB IDs		7SQK
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organelle Organization Centrosome Microtubule-based Process Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Cytoskeleton Organization Intermediate Filament Organization Protein Binding Structural Constituent Of Skin Epidermis Keratin Filament Organelle Assembly Intermediate Filament Identical Protein Binding Microtubule Organizing Center Organization Establishment Of Localization In Cell Supramolecular Fiber Organization Organelle Localization Intracellular Transport Centrosome Cycle Microtubule Binding Intracellular Protein Localization Protein Localization To Centrosome Metaphase Chromosome Alignment Cellular Component Assembly Protein Transport Cilium Organization Centriole Assembly Spindle Organization Cellular Localization Structural Molecule Activity Establishment Of Protein Localization Cilium Assembly Microtubule Establishment Of Organelle Localization Chromosome Localization BLOC-1 Complex Plasma Membrane Bounded Cell Projection Assembly Microtubule Cytoskeleton Organization Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Projection Assembly Mitotic Metaphase Chromosome Alignment Protein Localization To Cytoskeleton Spindle Pole Structural Constituent Of Cytoskeleton Vesicle Organization Centriole Centriole Replication Protein Localization To Organelle Endosomal Transport	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Elongin Complex Muscle Thin Filament Tropomyosin Ciliary Basal Body Centrosome Transcription Elongation By RNA Polymerase II Cytoskeleton Protein Binding DNA-templated Transcription Elongation Autophagosome Maturation Autophagosome Membrane Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Mitophagy Muscle Filament Sliding Spindle Pole
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