AP3M1 and AQP4

Number of citations of the paper that reports this interaction (PMID 11742978)
29

Data Source:
HPRD (in vitro)

		AP3M1	AQP4
Gene Name		adaptor-related protein complex 3, mu 1 subunit	aquaporin 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction External Side Of Plasma Membrane Basolateral Plasma Membrane T-tubule Protein Complex
	Molecular Function	Protein Binding Rab GTPase Binding	Water Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Porin Activity
	Biological Process	Protein Targeting To Lysosome Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport	Renal Water Homeostasis Transport Water Transport Female Pregnancy Sensory Perception Of Sound Response To Radiation Cellular Water Homeostasis Carbon Dioxide Transport Glycerol Transport Ion Transmembrane Transport Hyperosmotic Salinity Response Multicellular Organismal Water Homeostasis Protein Homooligomerization Response To Glucocorticoid Transmembrane Transport Renal Water Absorption Cellular Response To Interferon-gamma Cellular Response To Estradiol Stimulus
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis	Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins Aquaporin-mediated transport
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-Protein Interactions		8 interactors: AGTRAP AQP4 CRMP1 RSPH14 RUFY1 SIPA1L2 TGOLN2 TRIM9	4 interactors: AP2M1 AP3M1 CSNK2A1 CSNK2A2
Entrez ID		26985	361
HPRD ID		16496	02631
Ensembl ID			ENSG00000171885
Uniprot IDs		B4DRN6 Q9Y2T2	F1DSG4 P55087
PDB IDs			3GD8
Enriched GO Terms of Interacting Partners?		Negative Regulation Of SNARE Complex Assembly Carbon Dioxide Transport Renal Water Absorption Renal Water Transport Angiotensin-activated Signaling Pathway Regulation Of SNARE Complex Assembly Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Vesicle Fusion Hyperosmotic Salinity Response Glycerol Transport Renal Absorption Polyol Transport Regulation Of Vesicle-mediated Transport Cellular Water Homeostasis	Mitotic Spindle Checkpoint Movement Of Cell Or Subcellular Component Axon Guidance Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Axonogenesis Negative Regulation Of Proteasomal Protein Catabolic Process Axon Development Negative Regulation Of Cellular Protein Catabolic Process Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Neuron Projection Morphogenesis Negative Regulation Of Chromosome Organization Cell Morphogenesis Involved In Differentiation Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Neuron Development Mitotic Cell Cycle Checkpoint Cell Morphogenesis Regulation Of Proteasomal Protein Catabolic Process Neuron Differentiation Regulation Of Chromosome Organization Cell Projection Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Locomotion Regulation Of Cell Division Wnt Signaling Pathway Generation Of Neurons Negative Regulation Of Proteolysis Neurogenesis Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Regulation Of Protein Processing Cell Development Response To External Stimulus Regulation Of Mitotic Cell Cycle
Tagcloud ?			3rds aquaporin blindness contiguous demyelinating edss gray holocord ig longitudinally malaysia monophasic myelitis neuritis neuromyelitis nmo nmosd optic optica paroxysmal relapses relapsing seronegative seropositive seropositivity spasms tonic transverse vertebral
Tagcloud (Difference) ?			3rds aquaporin blindness contiguous demyelinating edss gray holocord ig longitudinally malaysia monophasic myelitis neuritis neuromyelitis nmo nmosd optic optica paroxysmal relapses relapsing seronegative seropositive seropositivity spasms tonic transverse vertebral
Tagcloud (Intersection) ?