AP3M1 and SIPA1L2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AP3M1	SIPA1L2
Gene Name		adaptor-related protein complex 3, mu 1 subunit	signal-induced proliferation-associated 1 like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Binding Rab GTPase Binding	GTPase Activator Activity
	Biological Process	Protein Targeting To Lysosome Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport	Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)	Immunoglobulin A ( 20694011)
Protein-Protein Interactions		8 interactors: AGTRAP AQP4 CRMP1 RSPH14 RUFY1 SIPA1L2 TGOLN2 TRIM9	3 interactors: AP3M1 ORC5 TGM2
Entrez ID		26985	57568
HPRD ID		16496	15346
Ensembl ID			ENSG00000116991
Uniprot IDs		B4DRN6 Q9Y2T2	Q9P2F8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of SNARE Complex Assembly Carbon Dioxide Transport Renal Water Absorption Renal Water Transport Angiotensin-activated Signaling Pathway Regulation Of SNARE Complex Assembly Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Vesicle Fusion Hyperosmotic Salinity Response Glycerol Transport Renal Absorption Polyol Transport Regulation Of Vesicle-mediated Transport Cellular Water Homeostasis	Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Salivary Gland Cavitation Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Protein Targeting To Lysosome Protein Localization To Lysosome Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Mitochondrial Calcium Ion Homeostasis Anterograde Synaptic Vesicle Transport Protein Targeting To Vacuole Establishment Of Protein Localization To Vacuole Anterograde Axon Cargo Transport Branching Involved In Salivary Gland Morphogenesis Apoptotic Cell Clearance Endoplasmic Reticulum Calcium Ion Homeostasis DNA Replication Initiation Blood Vessel Remodeling Salivary Gland Morphogenesis Peptide Cross-linking Lysosomal Transport Salivary Gland Development Axon Cargo Transport Positive Regulation Of Smooth Muscle Cell Proliferation Exocrine System Development Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
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