AP3M1 and TGOLN2

Number of citations of the paper that reports this interaction (PMID 15254094)
68

Data Source:
HPRD (two hybrid, in vitro)

		AP3M1	TGOLN2
Gene Name		adaptor-related protein complex 3, mu 1 subunit	trans-golgi network protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane	Nucleoplasm Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Transport Vesicle
	Molecular Function	Protein Binding Rab GTPase Binding	Protein Binding
	Biological Process	Protein Targeting To Lysosome Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-Protein Interactions		8 interactors: AGTRAP AQP4 CRMP1 RSPH14 RUFY1 SIPA1L2 TGOLN2 TRIM9	10 interactors: AP1M1 AP1M2 AP2M1 AP3M1 AP4M1 ITGB1 KRTAP10-9 PPP1R9A PPP1R9B PRKD2
Entrez ID		26985	10618
HPRD ID		16496	04343
Ensembl ID			ENSG00000152291
Uniprot IDs		B4DRN6 Q9Y2T2	O43493
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of SNARE Complex Assembly Carbon Dioxide Transport Renal Water Absorption Renal Water Transport Angiotensin-activated Signaling Pathway Regulation Of SNARE Complex Assembly Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Vesicle Fusion Hyperosmotic Salinity Response Glycerol Transport Renal Absorption Polyol Transport Regulation Of Vesicle-mediated Transport Cellular Water Homeostasis	Regulation Of Defense Response To Virus By Virus Intracellular Protein Transport Cellular Protein Localization Protein Transport Regulation Of Defense Response To Virus Establishment Of Protein Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Intracellular Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Protein Localization Establishment Of Localization In Cell Viral Process Regulation Of Immune System Process Cellular Localization Antigen Processing And Presentation Of Peptide Antigen Vesicle-mediated Transport Golgi Vesicle Transport Antigen Processing And Presentation Neuron Projection Development Regulation Of Protein Localization To Plasma Membrane Membrane Organization Neuron Development Neuron Differentiation Calcium-mediated Signaling Cell Projection Organization Immune System Process Protein Kinase D Signaling Regulation Of Opioid Receptor Signaling Pathway Cellular Response To Morphine Positive Regulation Of Histone Deacetylase Activity Regulation Of Collagen Catabolic Process Dendrite Development Actin Cytoskeleton Organization Response To Growth Factor Second-messenger-mediated Signaling Actin Filament-based Process Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Response To Isoquinoline Alkaloid Calcium-independent Cell-matrix Adhesion Regulation Of Cell Growth By Extracellular Stimulus Movement Of Cell Or Subcellular Component Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Generation Of Neurons Formation Of Radial Glial Scaffolds Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Histone Deacetylase Activity Cytoplasmic Transport Positive Regulation Of Deacetylase Activity
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