NUP214 and TNPO1

Number of citations of the paper that reports this interaction (PMID 9144189)
59

Data Source:
HPRD (in vitro)

		NUP214	TNPO1
Gene Name		nucleoporin 214kDa	transportin 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Poly(A) RNA Binding
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Regulation Of Cell Cycle Transmembrane Transport	Protein Import Into Nucleus, Translocation Organelle Organization Gene Expression Viral Process
Pathways		Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport HuR stabilizes mRNA M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Regulation of mRNA stability by proteins that bind AU-rich elements Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport	Regulation of mRNA stability by proteins that bind AU-rich elements Organelle biogenesis and maintenance Assembly of the primary cilium Tristetraprolin (TTP) destabilizes mRNA Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: APC CLEC4G DDX19B IPO5 NFX1 NUP107 NUP88 NUPL2 NXF1 NXF2 NXF3 SMAD2 SMAD3 SMAD4 TNPO1 XPO1 XPO5 XPOT ZFP36	17 interactors: ELAVL1 HIST2H2BE HIST3H3 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19
Entrez ID		8021	3842
HPRD ID		00258	04210
Ensembl ID		ENSG00000126883	ENSG00000083312
Uniprot IDs		P35658	Q92973
PDB IDs		2OIT 3FHC 3FMO 3FMP	1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ
Enriched GO Terms of Interacting Partners?		Nucleocytoplasmic Transport Nuclear Transport Nuclear Export RNA Transport RNA Localization MRNA Transport Cytoplasmic Transport RNA Export From Nucleus Viral Process Gene Expression MRNA Export From Nucleus Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Transport SMAD Protein Complex Assembly Establishment Of Protein Localization Gene Silencing By RNA Protein Localization Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing Positive Regulation Of Epithelial To Mesenchymal Transition Protein Export From Nucleus Gene Silencing By MiRNA Mitotic Nuclear Envelope Disassembly Transforming Growth Factor Beta Receptor Signaling Pathway Posttranscriptional Gene Silencing Nuclear Envelope Disassembly Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Envelope Organization Somatic Stem Cell Maintenance Regulation Of Transforming Growth Factor Beta2 Production Paraxial Mesoderm Morphogenesis Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Glucose Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Endoderm Development Hexose Transport Embryonic Pattern Specification	Cytoplasmic Transport Viral Life Cycle Viral Process Viral Transcription Intracellular Transport Establishment Of Protein Localization To Organelle MRNA Transport RNA Transport Protein Targeting Nucleocytoplasmic Transport Nuclear Transport RNA Localization Protein Localization To Organelle Establishment Of Localization In Cell Nuclear Import Cellular Localization Gene Expression Intracellular Protein Transport Protein Transport Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Nuclear Export Nuclear Envelope Disassembly Membrane Organization Cellular Protein Localization Protein Localization Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Regulation Of Glucose Transport Establishment Of Protein Localization To Endoplasmic Reticulum MRNA Metabolic Process Protein Import Into Nucleus Transport Nucleus Organization Protein Localization To Endoplasmic Reticulum Carbohydrate Transport Protein Import Protein Targeting To Membrane Protein Localization To Nucleus Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Nuclear Pore Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process
Tagcloud ?		acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16	box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately
Tagcloud (Difference) ?		acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16	box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately
Tagcloud (Intersection) ?