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NUP214 and DDX19B
Number of citations of the paper that reports this interaction (PubMedID
10428971
)
0
Data Source:
HPRD
(in vitro)
NUP214
DDX19B
Description
nucleoporin 214
DEAD-box helicase 19B
Image
GO Annotations
Cellular Component
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Cytosol
Cytoplasmic Side Of Nuclear Pore
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Cytoplasm
Cytoplasmic Stress Granule
Membrane
Extracellular Exosome
Molecular Function
Nuclear Export Signal Receptor Activity
Protein Binding
Nuclear Localization Sequence Binding
Structural Constituent Of Nuclear Pore
Nucleotide Binding
Nucleic Acid Binding
RNA Binding
RNA Helicase Activity
MRNA Binding
Helicase Activity
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Biological Process
RNA Export From Nucleus
MRNA Export From Nucleus
Protein Import Into Nucleus
Protein Export From Nucleus
Intracellular Protein Transport
Nucleocytoplasmic Transport
Protein Transport
Regulation Of Nucleocytoplasmic Transport
MRNA Transport
Regulation Of Cell Cycle
MRNA Export From Nucleus
Poly(A)+ MRNA Export From Nucleus
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
IPs transport between nucleus and cytosol
IP3 and IP4 transport between cytosol and nucleus
IP6 and IP7 transport between cytosol and nucleus
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
HuR (ELAVL1) binds and stabilizes mRNA
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
Aspartate aminotransferase levels (
31219225
)
Apolipoprotein B levels (
32203549
)
Brain morphology (MOSTest) (
32665545
)
Malaria (
31844061
)
Pursuit maintenance gain (
29064472
)
Systolic blood pressure (
30578418
)
Interacting Genes
19 interacting genes:
APC
CLEC4G
DDX19B
IPO5
NUP107
NUP42
NUP88
NXF1
NXF2
SMAD2
SMAD3
SMAD4
SUMO2
TNPO1
TSG101
XPO1
XPO5
XPOT
ZFP36
16 interacting genes:
APP
B3GALT4
CEBPA
DCK
EIF4G3
FOXP1
IKBKG
NUP214
POT1
PRPSAP1
RACK1
RWDD2B
SKP1
TERF1
UBC
XPO7
Entrez ID
8021
11269
HPRD ID
00258
05781
Ensembl ID
ENSG00000126883
ENSG00000157349
Uniprot IDs
B7ZAV2
P35658
A0A0U4B4U6
H3BQK0
Q9UMR2
PDB IDs
2OIT
3FHC
3FMO
3FMP
5DIS
7R5J
7R5K
3EWS
3FHC
3FHT
3FMO
3FMP
3G0H
6B4I
6B4J
6B4K
Enriched GO Terms of Interacting Partners
?
RNA Transport
Nuclear Transport
Nucleocytoplasmic Transport
RNA Export From Nucleus
Nuclear Export
Nucleobase-containing Compound Transport
MRNA Transport
Nuclear Pore
MRNA Export From Nucleus
Intracellular Transport
Cellular Localization
Establishment Of Localization In Cell
Intracellular Protein Transport
RNA Binding
Nuclear Envelope
Protein Transport
SMAD Protein Complex
Heteromeric SMAD Protein Complex
Protein Localization To Nucleus
Establishment Of Protein Localization
Nuclear Export Signal Receptor Activity
Primary MiRNA Processing
Protein Import Into Nucleus
Import Into Nucleus
I-SMAD Binding
Cytosol
MRNA Binding
Nuclear Localization Sequence Binding
Structural Constituent Of Nuclear Pore
Activin Responsive Factor Complex
Paraxial Mesoderm Morphogenesis
Post-transcriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery
Poly(A)+ MRNA Export From Nucleus
Kinetochore
SMAD Protein Signal Transduction
R-SMAD Binding
Nucleoplasm
Activin Receptor Signaling Pathway
Intracellular Protein Localization
Establishment Of Protein Localization To Organelle
Endoderm Development
Protein Export From Nucleus
MiRNA Processing
Mesoderm Morphogenesis
Pericardium Development
Ribosomal Large Subunit Export From Nucleus
Nucleus
Trophoblast Cell Migration
Ribosomal Small Subunit Export From Nucleus
Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery
Shelterin Complex
Positive Regulation Of Proteolysis
Protein Homodimerization Activity
Nuclear Telomere Cap Complex
Telomeric Loop Disassembly
Telomere Capping
Telomeric D-loop Disassembly
G-rich Strand Telomeric DNA Binding
Nuclear Export Signal Receptor Activity
Regulation Of Response To Endoplasmic Reticulum Stress
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Telomere Maintenance Via Telomerase
Molecular Function Activator Activity
RNA-templated DNA Biosynthetic Process
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Telomere Maintenance Via Telomere Lengthening
Telomeric DNA Binding
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Antigen Receptor-mediated Signaling Pathway
Amyloid-beta Complex
Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Growth Cone Lamellipodium
Regulation Of Response To Calcium Ion
Amylin Binding
Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Proteolysis
Positive Regulation Of Toll Signaling Pathway
Nucleoplasm
Regulation Of Ubiquitin-dependent Protein Catabolic Process
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Establishment Of Protein Localization To Telomere
Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere
Negative Regulation Of Telomere Maintenance
Negative Regulation Of Establishment Of RNA Localization To Telomere
Positive Regulation Of Shelterin Complex Assembly
Cytoplasmic Side Of Nuclear Pore
Protein Export From Nucleus
Ganglioside Galactosyltransferase Activity
Positive Regulation Of DNA Strand Elongation
Positive Regulation Of Telomeric D-loop Disassembly
G-rich Single-stranded DNA Binding
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Response To Endoplasmic Reticulum Stress
Positive Regulation Of Protein Catabolic Process
Identical Protein Binding
Regulation Of Telomere Maintenance Via Telomere Lengthening
Acetylcholine Receptor Activator Activity
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