CTC1 and APPBP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CTC1	APPBP2
Gene Name		CTS telomere maintenance complex component 1	amyloid beta precursor protein (cytoplasmic tail) binding protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleus Stn1-Ten1 Complex	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Single-stranded DNA Binding Protein Binding	Microtubule Motor Activity Protein Binding
	Biological Process	Telomere Maintenance Cellular Response To DNA Damage Stimulus Regulation Of G2/M Transition Of Mitotic Cell Cycle Telomere Maintenance Via Telomere Lengthening Multicellular Organism Growth Positive Regulation Of DNA Replication Positive Regulation Of Fibroblast Proliferation Spleen Development Thymus Development Bone Marrow Development Hematopoietic Stem Cell Proliferation Replicative Senescence	Intracellular Protein Transport Metabolic Process Intracellular Transport
Pathways
Drugs
Diseases
GWAS		Telomere length ( 23001564)
Protein-Protein Interactions		2 interactors: APPBP2 TPP1	79 interactors: AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 DCD DHRS2 DPEP1 EID3 EPT1 ERO1L FAM19A4 FAM92A1 FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 HIPK4 HIST1H2AK HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MGC34796 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		80169	10513
HPRD ID		07980	05616
Ensembl ID			ENSG00000062725
Uniprot IDs		Q2NKJ3	Q92624
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Single-stranded Telomeric DNA Binding Regulation Of Establishment Of Blood-brain Barrier Intermembrane Transport Vitamin E Metabolic Process Protection From Non-homologous End Joining At Telomere Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Telomerase Activity Telomere Assembly Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Peptide Catabolic Process Regulation Of Telomerase Activity Intracellular Protein Transport Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Intracellular PH Reduction PH Reduction Protein Localization To Chromosome Bone Resorption Response To PH Positive Regulation Of DNA Binding Cellular Protein Localization Protein Transport Regulation Of Intracellular PH Vitamin Transport Regulation Of DNA Biosynthetic Process Establishment Of Protein Localization Regulation Of Cellular PH Negative Regulation Of DNA Replication Intracellular Transport Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Lysosome Organization Positive Regulation Of Nuclease Activity Bone Remodeling Positive Regulation Of DNA Replication Regulation Of PH Telomere Maintenance Neuromuscular Process Controlling Balance Protein Localization Regulation Of DNA Binding Establishment Of Localization In Cell Negative Regulation Of Chromosome Organization Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of DNA Metabolic Process Cellular Response To Unfolded Protein Vacuole Organization ER-nucleus Signaling Pathway	Regulation Of Defense Response To Virus By Host Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homocysteine Metabolic Process Cellular Response To Organic Substance
Tagcloud ?		blepharitis bmf congenita dermatologist dkc1 dyskeratosis ectropion entropion epiphora exudative eyelashes hoyeraal hreidarsson lacy leukodepleted multicolor nails nhp2 nop10 otolaryngologist pigmentation reticular revesz taurodauntism terc tinf2 triad trichiasis wrap53	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?		blepharitis bmf congenita dermatologist dkc1 dyskeratosis ectropion entropion epiphora exudative eyelashes hoyeraal hreidarsson lacy leukodepleted multicolor nails nhp2 nop10 otolaryngologist pigmentation reticular revesz taurodauntism terc tinf2 triad trichiasis wrap53	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?