AAGAB and UNC119

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		AAGAB	UNC119
Description		alpha and gamma adaptin binding protein	unc-119 lipid binding chaperone
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GO Annotations	Cellular Component	Cytoplasm Cytosol Nuclear Speck	Spindle Pole Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Intercellular Bridge Synapse Spindle Midzone
	Molecular Function	Protein Binding	Protein Binding Lipid Binding
	Biological Process	Protein Transport	Mitotic Cytokinesis Endocytosis Chemical Synaptic Transmission Nervous System Development Visual Perception Phototransduction Protein Transport Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Allergic rhinitis ( 30013184) Asthma ( 31619474 31959851 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) FEV1 ( 30804560) Keratoconus ( 33649486) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Proportion of activated microglia (midfrontal cortex) ( 30679421) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		4 interacting genes: AP2S1 EIF3C HEATR1 UNC119	104 interacting genes: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CFTR CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A KRTAP1-3 KRTAP9-3 KRTAP9-8 LAMA4 LCK LIG4 LRIF1 LUC7L2 LYN MAP3K20 MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PLPP2 PPA1 PPP3CA PPP3CC PSMD11 PSMD2 PTPRS QTRT1 RAP1B RASSF6 RBPMS2 RCAN3 RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TMEM200A TP53BP2 TP53I3 TP53INP1 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZFP64 ZNF24
Entrez ID		79719	9094
HPRD ID		07754	04927
Ensembl ID		ENSG00000103591	ENSG00000109103
Uniprot IDs		Q6PD74	K7EN86 Q13432
PDB IDs		7TWD	3GQQ 3RBQ 4GOJ 4GOK 5L7K 6H6A 7UMO 9GKG
Enriched GO Terms of Interacting Partners?		Pigment Granule Localization Establishment Of Melanosome Localization Regulation Of Response To Food Microtubule Anchoring At Centrosome Pericentriolar Material Sensory Perception Sperm Flagellum Assembly Regulation Of Cilium Beat Frequency Mitotic Cytokinesis Visual Perception Protein Localization To Non-motile Cilium BBSome Maintenance Of Protein Location In Nucleus Intracellular Protein Localization Photoreceptor Cell Outer Segment Organization Retinal Rod Cell Development Negative Regulation Of Appetite Melanosome Localization Protein Transport Response To Leptin Establishment Of Protein Localization Protein Localization To Photoreceptor Outer Segment Brain Morphogenesis Microtubule Anchoring Cytoskeleton-dependent Cytokinesis Striatum Development Fat Pad Development Sensory Perception Of Light Stimulus Erythrocyte Homeostasis Melanosome Transport Leptin-mediated Signaling Pathway Ventricular System Development Face Development Sensory Processing Pigment Granule Transport Dynactin Binding Regulation Of Non-motile Cilium Assembly Retina Homeostasis Protein Localization To Centrosome Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Microtubule Anchoring At Microtubule Organizing Center Regulation Of Appetite Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Negative Regulation Of Systemic Arterial Blood Pressure Clathrin Adaptor Activity Postsynaptic Neurotransmitter Receptor Internalization AP-2 Adaptor Complex Endolysosome Membrane Endocytosis Regulation Of Endocytosis	Fc-gamma Receptor Signaling Pathway Fc Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Lymphocyte Activation Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Glutamatergic Synapse Leukocyte Migration Positive Regulation Of Cell Activation Cytosol Enzyme Binding Positive Regulation Of Cell-cell Adhesion Protein Binding T Cell Receptor Binding RAGE Receptor Binding Positive Regulation Of Cell Adhesion Intracellular Signal Transduction Regulation Of Lymphocyte Activation Positive Regulation Of Cell Development Regulation Of Calcium Ion Import Across Plasma Membrane Cytoplasm Nucleus T Cell Activation Positive Regulation Of Monoatomic Ion Transmembrane Transport Gamma-delta T Cell Receptor Complex Lymphocyte Activation Regulation Of Leukocyte Cell-cell Adhesion Calcium-dependent Protein Binding Regulation Of T Cell Activation Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Cellular Developmental Process T Cell Costimulation Positive Regulation Of Leukocyte Differentiation T Cell Receptor Complex Intracellular Signaling Cassette CD8 Receptor Binding Nucleotide Binding Gamma-delta T Cell Activation Negative Regulation Of Cell Development Peptidyl-tyrosine Phosphorylation Regulation Of Mitotic Cell Cycle Phagocytosis Regulation Of Leukocyte Proliferation Response To Gamma Radiation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Schaffer Collateral - CA1 Synapse
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