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ARHGAP10 and PKN1
Number of citations of the paper that reports this interaction (PMID
11432776
)
10
Data Source:
HPRD
(in vivo, in vitro)
ARHGAP10
PKN1
Gene Name
Rho GTPase activating protein 10
protein kinase N1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Plasma Membrane
Perinuclear Region Of Cytoplasm
Nucleus
Cytoplasm
Endosome
Plasma Membrane
Cytoplasmic Membrane-bounded Vesicle
Midbody
Cleavage Furrow
Molecular Function
Rho GTPase Activator Activity
Protein Binding
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Kinase C Activity
Protein Kinase C Binding
Protein Binding
ATP Binding
GTP-Rho Binding
Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Histone Kinase Activity (H3-T11 Specific)
Histone Binding
Histone Deacetylase Binding
Rac GTPase Binding
Androgen Receptor Binding
Biological Process
Apoptotic Process
Cytoskeleton Organization
Small GTPase Mediated Signal Transduction
Positive Regulation Of Rho GTPase Activity
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Small GTPase Mediated Signal Transduction
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Protein Phosphorylation
Hyperosmotic Response
Signal Transduction
Activation Of JUN Kinase Activity
Epithelial Cell Migration
Histone H3-T11 Phosphorylation
Regulation Of Cell Motility
Pathways
Rho GTPase cycle
Regulation of PAK-2p34 activity by PS-GAP/RHG10
Signaling by Rho GTPases
Programmed Cell Death
Regulation of Apoptosis
Drugs
Diseases
GWAS
Immune reponse to smallpox (secreted IL-12p40) (
22610502
)
QT interval (
20031603
)
Protein-Protein Interactions
6 interactors:
CDC42
PAK2
PKN1
PKN3
RHOA
YWHAQ
40 interactors:
ACTN1
AKAP9
ARHGAP10
ARHGAP26
CASP3
CCDC85B
CCNT2
CD44
CDC25C
CDR2
CEP57L1
GOLGA2
HDAC5
HDAC6
HIST1H1A
HIST2H3C
HOMER3
KRT15
KRT31
MAP2K6
MAPK12
MAPT
MARCKS
MBP
MID1
NEFH
NEFL
NEUROD2
PDPK1
PLD1
RHOA
SPRR2D
SSX2IP
TNFRSF1B
TRAF1
TRAF2
VIM
WBSCR22
ZFAND6
ZNF282
Entrez ID
79658
5585
HPRD ID
07949
03019
Ensembl ID
ENSG00000071205
ENSG00000123143
Uniprot IDs
A1A4S6
Q16512
PDB IDs
1CXZ
1URF
2RMK
Enriched GO Terms of Interacting Partners
?
Substantia Nigra Development
Neural Nucleus Development
Midbrain Development
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Locomotion
Positive Regulation Of Signal Transduction
Movement Of Cell Or Subcellular Component
Intracellular Signal Transduction
Positive Regulation Of Intracellular Transport
Cell Migration
Cell Motility
Positive Regulation Of Cytokinesis
Axon Guidance
Regulation Of Cytokinesis
Regulation Of Intracellular Transport
Regulation Of Signal Transduction
Signal Transduction
T Cell Costimulation
Positive Regulation Of Kinase Activity
Signaling
Regulation Of Signaling
Cell Communication
Axonogenesis
Positive Regulation Of Transferase Activity
Ephrin Receptor Signaling Pathway
Epithelial Cell Migration
Axon Development
Epithelium Migration
Cell Morphogenesis Involved In Neuron Differentiation
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Chemotaxis
Small GTPase Mediated Signal Transduction
Positive Regulation Of Cell Death
Neuron Projection Morphogenesis
Positive Regulation Of JNK Cascade
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Cell Division
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Stress-activated MAPK Cascade
Cellular Response To Stimulus
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Hair Follicle Cell Proliferation
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Transport
Regulation Of Protein Kinase Activity
Brain Development
Positive Regulation Of Intracellular Protein Transport
Regulation Of Kinase Activity
Organelle Organization
Cytoskeleton Organization
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Cellular Response To Organic Substance
Response To Organic Substance
Response To Tumor Necrosis Factor
Regulation Of Microtubule-based Movement
Intermediate Filament Organization
Response To Growth Factor
Microtubule Cytoskeleton Organization
Regulation Of Cellular Component Organization
Developmental Process
Regulation Of Cellular Process
Neurofilament Bundle Assembly
Response To Stress
Regulation Of Cellular Component Movement
Regulation Of Cell Death
Microtubule-based Process
Regulation Of Cell Differentiation
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Metabolic Process
Intermediate Filament Bundle Assembly
Defense Response
Epithelium Development
Intermediate Filament Cytoskeleton Organization
Cell Communication
Intermediate Filament-based Process
Microtubule-based Transport
Regulation Of Intracellular Signal Transduction
Anatomical Structure Development
Regulation Of Apoptotic Process
Cytoskeleton-dependent Intracellular Transport
Regulation Of Metabolic Process
Response To Wounding
Response To Stimulus
Regulation Of Cell Projection Organization
Response To Cytokine
Regulation Of Axonogenesis
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Stimulus
Signaling
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cell Differentiation
Regulation Of Microtubule-based Process
Regulation Of Phosphorylation
Regulation Of Microtubule Polymerization Or Depolymerization
Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
accordingly
androgen
ar
blocks
chip
colocalization
driver
enriched
epigenomic
establishing
facilitates
h3k4
h3k4me3
h3t11p
hyperexpressed
integrator
interacts
marked
mll
mll1
promoters
prostate
recruitment
seq
set1
severely
threonine
tri
wdr5
Tagcloud (Difference)
?
accordingly
androgen
ar
blocks
chip
colocalization
driver
enriched
epigenomic
establishing
facilitates
h3k4
h3k4me3
h3t11p
hyperexpressed
integrator
interacts
marked
mll
mll1
promoters
prostate
recruitment
seq
set1
severely
threonine
tri
wdr5
Tagcloud (Intersection)
?