ARHGAP10

Gene Name		Rho GTPase activating protein 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Rho GTPase Activator Activity Protein Binding
	Biological Process	Apoptotic Process Cytoskeleton Organization Small GTPase Mediated Signal Transduction Positive Regulation Of Rho GTPase Activity Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Regulation of PAK-2p34 activity by PS-GAP/RHG10 Signaling by Rho GTPases Programmed Cell Death Regulation of Apoptosis
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502) QT interval ( 20031603)
Protein-protein Interactions		6 interactors: CDC42 PAK2 PKN1 PKN3 RHOA YWHAQ
Entrez ID		79658
HPRD ID		07949
Ensembl ID		ENSG00000071205
Uniprot IDs		A1A4S6
PDB IDs
Enriched GO Terms of Interacting Partners?		Substantia Nigra Development Neural Nucleus Development Midbrain Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Locomotion Positive Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Intracellular Signal Transduction Positive Regulation Of Intracellular Transport Cell Migration Cell Motility Positive Regulation Of Cytokinesis Axon Guidance Regulation Of Cytokinesis Regulation Of Intracellular Transport Regulation Of Signal Transduction Signal Transduction T Cell Costimulation Positive Regulation Of Kinase Activity Signaling Regulation Of Signaling Cell Communication Axonogenesis Positive Regulation Of Transferase Activity Ephrin Receptor Signaling Pathway Epithelial Cell Migration Axon Development Epithelium Migration Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Chemotaxis Small GTPase Mediated Signal Transduction Positive Regulation Of Cell Death Neuron Projection Morphogenesis Positive Regulation Of JNK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Division Regulation Of Establishment Of Protein Localization Positive Regulation Of Stress-activated MAPK Cascade Cellular Response To Stimulus Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Hair Follicle Cell Proliferation Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Transport Regulation Of Protein Kinase Activity Brain Development Positive Regulation Of Intracellular Protein Transport Regulation Of Kinase Activity
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