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GCC1 and LZTS2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
GCC1
LZTS2
Gene Name
GRIP and coiled-coil domain containing 1
leucine zipper, putative tumor suppressor 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Cytoplasm
Golgi Apparatus
Plasma Membrane
Cytoplasm
Centrosome
Microtubule
Midbody
Molecular Function
Protein Binding
Protein Binding
Biological Process
Protein Targeting To Golgi
Cytokinesis
Kidney Development
Mitotic Nuclear Division
Negative Regulation Of Cell Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS
Type 2 diabetes (
22158537
)
Protein-Protein Interactions
36 interactors:
ABI2
AMOTL2
APP
ARL1
ATF4
ATN1
BIRC2
BRCA1
C1orf94
CCDC85B
CEP57
CEP70
COIL
CPSF7
DNAJA3
FBF1
GLI1
GOLGA2
GTF2I
IKBKG
ITSN1
KIAA0753
KIAA1217
LZTS2
MCRS1
NAB2
NAV1
NECAB2
NINL
OIP5
PAK7
SMARCD1
TFIP11
TRIM29
USHBP1
ZNF276
172 interactors:
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARHGAP32
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P5
BYSL
C14orf105
C19orf66
C1orf109
C20orf195
C6orf165
C8orf33
CARD9
CBX8
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CEP57L1
CHCHD3
CLIP4
CNNM3
COPB1
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DYRK1A
DYRK1B
DYRK2
EHHADH
EIF3D
EIF4E2
FAM103A1
FAM107A
FAM124B
FAM161A
FAM74A4
FANCL
FBF1
FEM1C
FGF12
FKBP6
FRG1
FRMD6
GCC1
GEM
GFI1B
GMCL1P1
GNL3L
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HSPD1
IQCE
KAT5
KAZN
KIAA1683
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
MAB21L3
MAGEB4
MEMO1
MORF4L1
MORF4L2
MORN3
MOS
MTA1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
OTUB2
PAK7
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R18
PQBP1
PRKAB2
PSMA1
QARS
RAC1
RAD51D
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3RF2
SLC15A3
SLC25A6
SLU7
SMIM3
SNHG11
SNW1
SNX31
SPATA2
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
TBC1D7
TCEA2
TCHP
TEAD4
THAP10
THAP7
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TTC23
TXNL4A
USF2
USP2
UTP14C
WDYHV1
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
Entrez ID
79571
84445
HPRD ID
07599
14341
Ensembl ID
ENSG00000179562
ENSG00000107816
Uniprot IDs
A4D0Z4
Q96CN9
Q9BRK4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Organelle Organization
Transcription, DNA-templated
RNA Metabolic Process
Regulation Of Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Intracellular Signal Transduction
Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Anatomical Structure Development
Developmental Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Toxin Metabolic Process
Negative Regulation Of Cell Death
Mitotic Cell Cycle
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase III Promoter
Nitrogen Compound Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Ubiquitination
Cell Communication
Positive Regulation Vascular Endothelial Growth Factor Production
Signal Transduction
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
System Development
Multicellular Organismal Development
Cellular Process
NIK/NF-kappaB Signaling
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Biosynthetic Process
Cell Cycle
Positive Regulation Of Histone H4-K20 Methylation
Spliceosomal Complex Disassembly
Positive Regulation Of Histone H4-K16 Acetylation
Positive Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Protein Monoubiquitination
Positive Regulation Of Protein K48-linked Ubiquitination
RNA Metabolic Process
Gene Expression
Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of Gene Expression
Nitrogen Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Ribonucleoprotein Complex Biogenesis
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Viral Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription, DNA-templated
Regulation Of Cellular Process
Positive Regulation Of Cellular Metabolic Process
Organelle Organization
RNA Processing
Ribonucleoprotein Complex Assembly
Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecular Complex Assembly
Negative Regulation Of Gene Expression
Cellular Response To DNA Damage Stimulus
RNA Splicing
MRNA Processing
Regulation Of Protein Metabolic Process
Transcription From RNA Polymerase II Promoter
MRNA Splicing, Via Spliceosome
MRNA Metabolic Process
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Cell Cycle
Negative Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of T Cell Activation
Cellular Process
Positive Regulation Of Homotypic Cell-cell Adhesion
Regulation Of Cell Cycle
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Tagcloud
?
a549
anticancer
chemotherapeutic
clones
credits
effectively
exposing
gltscr2
lats1
making
mdr1
nf1
paclitaxel
panel
predetermined
profiling
pten
regards
screen
screened
shrna
shrnas
smad4
st14
suppressors
tumorigenesis
tumorigenic
vhl
wt1
Tagcloud (Difference)
?
a549
anticancer
chemotherapeutic
clones
credits
effectively
exposing
gltscr2
lats1
making
mdr1
nf1
paclitaxel
panel
predetermined
profiling
pten
regards
screen
screened
shrna
shrnas
smad4
st14
suppressors
tumorigenesis
tumorigenic
vhl
wt1
Tagcloud (Intersection)
?