LZTS2 and PKP4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LZTS2	PKP4
Gene Name		leucine zipper, putative tumor suppressor 2	plakophilin 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Microtubule Midbody	Spindle Pole Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Desmosome Midbody Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Mitotic Spindle
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cytokinesis Kidney Development Mitotic Nuclear Division Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Microtubule Severing Nuclear Export Spindle Midzone Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Localization To Nucleus	Cell-cell Junction Assembly Cell-cell Signaling Single Organismal Cell-cell Adhesion Regulation Of Cell Adhesion Positive Regulation Of Rho GTPase Activity Positive Regulation Of Cytokinesis
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		172 interactors: ABT1 AEN ANKRD11 ANKRD36BP1 AP1M1 ARHGAP32 ARMC7 ARNT2 ATPAF2 BAHD1 BEX2 BMS1P5 BYSL C14orf105 C19orf66 C1orf109 C20orf195 C6orf165 C8orf33 CARD9 CBX8 CCDC85B CCNC CCNG1 CCNK CDC23 CDK18 CDKL3 CEP57L1 CHCHD3 CLIP4 CNNM3 COPB1 CWF19L2 DCUN1D1 DGCR6 DGCR6L DYRK1A DYRK1B DYRK2 EHHADH EIF3D EIF4E2 FAM103A1 FAM107A FAM124B FAM161A FAM74A4 FANCL FBF1 FEM1C FGF12 FKBP6 FRG1 FRMD6 GCC1 GEM GFI1B GMCL1P1 GNL3L GPATCH2L GRB2 HLA-DPB1 HM13 HOMER2 HSPD1 IQCE KAT5 KAZN KIAA1683 KIF9 KIFC3 KPNA2 LASP1 LCK LIN37 LMO1 LMO2 MAB21L3 MAGEB4 MEMO1 MORF4L1 MORF4L2 MORN3 MOS MTA1 NCBP2 NCK2 NDE1 NEBL NEK6 NINL NIP7 OTUB2 PAK7 PITX1 PKP4 PLEKHN1 POLDIP3 POLR1C PPP1R18 PQBP1 PRKAB2 PSMA1 QARS RAC1 RAD51D RBFOX1 RBM15 RBM41 RBPMS RCOR3 RHNO1 RHOXF2 RIN1 RNF32 RNF41 RTP5 RUNX1T1 SCNM1 SH2D4A SH3RF2 SLC15A3 SLC25A6 SLU7 SMIM3 SNHG11 SNW1 SNX31 SPATA2 SPATA24 SPATC1L SPG7 SRSF2 STAC SUPV3L1 SUV39H1 TBC1D7 TCEA2 TCHP TEAD4 THAP10 THAP7 TNIP3 TRAF2 TRIM29 TRIM42 TSNAX TTC23 TXNL4A USF2 USP2 UTP14C WDYHV1 WT1-AS YTHDC1 ZBTB25 ZBTB38 ZGPAT ZKSCAN3 ZMAT1 ZMAT2 ZMYND19 ZNF20 ZNF250 ZNF417 ZNF426 ZNF446 ZNF490 ZNF512B ZNF572 ZNF581	18 interactors: ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBB2IP GABARAP GOLGA2 LNX1 LZTS2 MINK1 OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 TRIM23
Entrez ID		84445	8502
HPRD ID		14341	05043
Ensembl ID		ENSG00000107816	ENSG00000144283
Uniprot IDs		Q9BRK4	Q99569
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process Organelle Organization RNA Processing Ribonucleoprotein Complex Assembly Regulation Of Cellular Protein Metabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus RNA Splicing MRNA Processing Regulation Of Protein Metabolic Process Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Positive Regulation Of Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of T Cell Activation Cellular Process Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process	Cell Adhesion Adherens Junction Organization Single Organismal Cell-cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Bundle Of His Cell To Purkinje Myocyte Communication Cell-cell Junction Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cellular Component Assembly Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Cellular Response To Starvation Negative Regulation Of Canonical Wnt Signaling Pathway Cardiac Muscle Cell Action Potential Involved In Contraction Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cellular Response To Nutrient Levels Response To Starvation Cardiovascular System Development Cardiac Muscle Cell Action Potential Negative Regulation Of Wnt Signaling Pathway Autophagic Vacuole Assembly Cell Junction Assembly Regulation Of Protein Ubiquitination Intermediate Filament Cytoskeleton Organization Blood Vessel Development Intermediate Filament-based Process Cellular Response To Extracellular Stimulus Regulation Of Cardiac Muscle Cell Contraction Vasculature Development Cardiac Conduction Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Stress Macroautophagy Cajal-Retzius Cell Differentiation Positive Regulation Of Histone H3-K36 Methylation Regulation Of Pentose-phosphate Shunt Beta-amyloid Formation Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Membrane Potential Organelle Organization Cytoskeleton Organization Regulation Of Wnt Signaling Pathway Execution Phase Of Apoptosis Regulation Of Heart Rate Regulation Of Cellular Component Movement Regulation Of Cardiac Muscle Contraction Threonylcarbamoyladenosine Biosynthetic Process Basal Protein Localization
Tagcloud ?		a549 anticancer chemotherapeutic clones credits effectively exposing gltscr2 lats1 making mdr1 nf1 paclitaxel panel predetermined profiling pten regards screen screened shrna shrnas smad4 st14 suppressors tumorigenesis tumorigenic vhl wt1
Tagcloud (Difference) ?		a549 anticancer chemotherapeutic clones credits effectively exposing gltscr2 lats1 making mdr1 nf1 paclitaxel panel predetermined profiling pten regards screen screened shrna shrnas smad4 st14 suppressors tumorigenesis tumorigenic vhl wt1
Tagcloud (Intersection) ?