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LZTS2 and HLA-DPB1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
LZTS2
HLA-DPB1
Gene Name
leucine zipper, putative tumor suppressor 2
major histocompatibility complex, class II, DP beta 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Centrosome
Microtubule
Midbody
Golgi Membrane
Lysosomal Membrane
Plasma Membrane
Cell Surface
Endosome Membrane
ER To Golgi Transport Vesicle Membrane
Membrane
Transport Vesicle Membrane
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Trans-Golgi Network Membrane
MHC Class II Protein Complex
Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
Molecular Function
Protein Binding
Peptide Antigen Binding
Biological Process
Cytokinesis
Kidney Development
Mitotic Nuclear Division
Negative Regulation Of Cell Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Cytokine-mediated Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
T Cell Costimulation
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of T Cell Proliferation
T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Activation
Interferon-gamma-mediated Signaling Pathway
Pathways
Generation of second messenger molecules
Downstream TCR signaling
Costimulation by the CD28 family
Translocation of ZAP-70 to Immunological synapse
Interferon Signaling
Cytokine Signaling in Immune system
Interferon gamma signaling
TCR signaling
MHC class II antigen presentation
PD-1 signaling
Phosphorylation of CD3 and TCR zeta chains
Adaptive Immune System
Drugs
Diseases
GWAS
Aspirin exacerbated respiratory disease in asthmatics (
23180272
)
Hepatitis B (
21750111
19349983
)
Hepatitis B (viral clearance) (
22737229
)
Hepatitis B vaccine response (
21764829
)
Nephropathy (
21399633
)
Systemic sclerosis (
21779181
)
Wegener's granulomatosis (
23740775
)
Protein-Protein Interactions
172 interactors:
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARHGAP32
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P5
BYSL
C14orf105
C19orf66
C1orf109
C20orf195
C6orf165
C8orf33
CARD9
CBX8
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CEP57L1
CHCHD3
CLIP4
CNNM3
COPB1
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DYRK1A
DYRK1B
DYRK2
EHHADH
EIF3D
EIF4E2
FAM103A1
FAM107A
FAM124B
FAM161A
FAM74A4
FANCL
FBF1
FEM1C
FGF12
FKBP6
FRG1
FRMD6
GCC1
GEM
GFI1B
GMCL1P1
GNL3L
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HSPD1
IQCE
KAT5
KAZN
KIAA1683
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
MAB21L3
MAGEB4
MEMO1
MORF4L1
MORF4L2
MORN3
MOS
MTA1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
OTUB2
PAK7
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R18
PQBP1
PRKAB2
PSMA1
QARS
RAC1
RAD51D
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3RF2
SLC15A3
SLC25A6
SLU7
SMIM3
SNHG11
SNW1
SNX31
SPATA2
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
TBC1D7
TCEA2
TCHP
TEAD4
THAP10
THAP7
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TTC23
TXNL4A
USF2
USP2
UTP14C
WDYHV1
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
7 interactors:
CD74
COPB1
HLA-DPA1
LZTS2
ROBO2
RTN4
TRIP6
Entrez ID
84445
3115
HPRD ID
14341
00832
Ensembl ID
ENSG00000107816
Uniprot IDs
Q9BRK4
I4EC15
P04440
PDB IDs
3LQZ
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Gene Expression
Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of Gene Expression
Nitrogen Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Ribonucleoprotein Complex Biogenesis
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Viral Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription, DNA-templated
Regulation Of Cellular Process
Positive Regulation Of Cellular Metabolic Process
Organelle Organization
RNA Processing
Ribonucleoprotein Complex Assembly
Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecular Complex Assembly
Negative Regulation Of Gene Expression
Cellular Response To DNA Damage Stimulus
RNA Splicing
MRNA Processing
Regulation Of Protein Metabolic Process
Transcription From RNA Polymerase II Promoter
MRNA Splicing, Via Spliceosome
MRNA Metabolic Process
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Cell Cycle
Negative Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of T Cell Activation
Cellular Process
Positive Regulation Of Homotypic Cell-cell Adhesion
Regulation Of Cell Cycle
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Locomotion
Neuron Recognition
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Macrophage Migration Inhibitory Factor Signaling Pathway
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Positive Regulation Of Lymphocyte Proliferation
Positive Regulation Of Mononuclear Cell Proliferation
Regulation Of Cell Migration
Cell Recognition
Negative Regulation Of Negative Chemotaxis
Regulation Of Cell Motility
Signal Transduction
Regulation Of Chemotaxis
Regulation Of Cellular Component Movement
Apoptotic Process Involved In Luteolysis
Regulation Of Branching Morphogenesis Of A Nerve
Regulation Of Axonogenesis
Signaling
Cellular Response To Organic Substance
Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Regulation Of Negative Chemotaxis
Negative Regulation Of Mature B Cell Apoptotic Process
Cell Communication
Regulation Of Behavior
Regulation Of Protein Localization To Nucleus
Axon Midline Choice Point Recognition
Luteolysis
Release Of Cytoplasmic Sequestered NF-kappaB
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Axon Choice Point Recognition
Antigen Processing And Presentation Of Peptide Antigen
Positive Regulation Of Cell-cell Adhesion
Endoplasmic Reticulum Tubular Network Organization
Cellular Response To Stimulus
Olfactory Bulb Interneuron Development
Antigen Processing And Presentation
Telencephalon Development
Spindle Midzone Assembly
Positive Thymic T Cell Selection
Positive Regulation Of Dendritic Cell Antigen Processing And Presentation
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Negative Regulation Of B Cell Apoptotic Process
Kidney Development
Response To Organic Substance
COPI-coated Vesicle Budding
COPI Coating Of Golgi Vesicle
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Tagcloud
?
a549
anticancer
chemotherapeutic
clones
credits
effectively
exposing
gltscr2
lats1
making
mdr1
nf1
paclitaxel
panel
predetermined
profiling
pten
regards
screen
screened
shrna
shrnas
smad4
st14
suppressors
tumorigenesis
tumorigenic
vhl
wt1
Tagcloud (Difference)
?
a549
anticancer
chemotherapeutic
clones
credits
effectively
exposing
gltscr2
lats1
making
mdr1
nf1
paclitaxel
panel
predetermined
profiling
pten
regards
screen
screened
shrna
shrnas
smad4
st14
suppressors
tumorigenesis
tumorigenic
vhl
wt1
Tagcloud (Intersection)
?