LZTS2 and BYSL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LZTS2	BYSL
Gene Name		leucine zipper, putative tumor suppressor 2	bystin-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Microtubule Midbody	Nucleus Nucleolus Cytoplasm Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	Protein Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Cytokinesis Kidney Development Mitotic Nuclear Division Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Microtubule Severing Nuclear Export Spindle Midzone Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Localization To Nucleus	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation Cell Adhesion Female Pregnancy Cell Proliferation
Pathways
Drugs
Diseases
GWAS			Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Red blood cell count ( 20139978)
Protein-Protein Interactions		172 interactors: ABT1 AEN ANKRD11 ANKRD36BP1 AP1M1 ARHGAP32 ARMC7 ARNT2 ATPAF2 BAHD1 BEX2 BMS1P5 BYSL C14orf105 C19orf66 C1orf109 C20orf195 C6orf165 C8orf33 CARD9 CBX8 CCDC85B CCNC CCNG1 CCNK CDC23 CDK18 CDKL3 CEP57L1 CHCHD3 CLIP4 CNNM3 COPB1 CWF19L2 DCUN1D1 DGCR6 DGCR6L DYRK1A DYRK1B DYRK2 EHHADH EIF3D EIF4E2 FAM103A1 FAM107A FAM124B FAM161A FAM74A4 FANCL FBF1 FEM1C FGF12 FKBP6 FRG1 FRMD6 GCC1 GEM GFI1B GMCL1P1 GNL3L GPATCH2L GRB2 HLA-DPB1 HM13 HOMER2 HSPD1 IQCE KAT5 KAZN KIAA1683 KIF9 KIFC3 KPNA2 LASP1 LCK LIN37 LMO1 LMO2 MAB21L3 MAGEB4 MEMO1 MORF4L1 MORF4L2 MORN3 MOS MTA1 NCBP2 NCK2 NDE1 NEBL NEK6 NINL NIP7 OTUB2 PAK7 PITX1 PKP4 PLEKHN1 POLDIP3 POLR1C PPP1R18 PQBP1 PRKAB2 PSMA1 QARS RAC1 RAD51D RBFOX1 RBM15 RBM41 RBPMS RCOR3 RHNO1 RHOXF2 RIN1 RNF32 RNF41 RTP5 RUNX1T1 SCNM1 SH2D4A SH3RF2 SLC15A3 SLC25A6 SLU7 SMIM3 SNHG11 SNW1 SNX31 SPATA2 SPATA24 SPATC1L SPG7 SRSF2 STAC SUPV3L1 SUV39H1 TBC1D7 TCEA2 TCHP TEAD4 THAP10 THAP7 TNIP3 TRAF2 TRIM29 TRIM42 TSNAX TTC23 TXNL4A USF2 USP2 UTP14C WDYHV1 WT1-AS YTHDC1 ZBTB25 ZBTB38 ZGPAT ZKSCAN3 ZMAT1 ZMAT2 ZMYND19 ZNF20 ZNF250 ZNF417 ZNF426 ZNF446 ZNF490 ZNF512B ZNF572 ZNF581	65 interactors: AES AIMP2 APP BEND7 C1orf94 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 EMD EPS8 FAM9B FXR2 GMCL1 GOLGA2 HMBOX1 IKZF1 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LONRF1 LTV1 LZTS2 MID1 MID2 MIPOL1 MRFAP1L1 MTUS2 NECAB2 OLIG3 PDE4DIP PHC2 PNMA1 PNMA2 RALYL SMN2 SSX2IP STX11 TEKT1 THAP1 TNIP1 TRAF4 TRIM27 TRIM37 TRIM54 TRIP6 TRO TROAP UBE2H VPS37B ZBTB14 ZBTB8A ZFP64
Entrez ID		84445	705
HPRD ID		14341	04848
Ensembl ID		ENSG00000107816	ENSG00000112578
Uniprot IDs		Q9BRK4	Q13895
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process Organelle Organization RNA Processing Ribonucleoprotein Complex Assembly Regulation Of Cellular Protein Metabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus RNA Splicing MRNA Processing Regulation Of Protein Metabolic Process Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Positive Regulation Of Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of T Cell Activation Cellular Process Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process	Gene Expression Protein Localization To Microtubule RNA Metabolic Process Regulation Of Protein Binding Transcription, DNA-templated Negative Regulation Of Cytoskeleton Organization RNA Biosynthetic Process Cell Adhesion Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Protein Complex Disassembly Negative Regulation Of Biosynthetic Process Dendritic Cell Migration Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Protein Modification By Small Protein Conjugation Regulation Of Viral Release From Host Cell Protein K11-linked Ubiquitination Regulation Of Protein Depolymerization Regulation Of Cellular Process Negative Regulation Of RNA Biosynthetic Process Organelle Organization Regulation Of Binding Regulation Of Metabolic Process Regulation Of Protein Complex Disassembly Cellular Macromolecule Biosynthetic Process Immune System Process Macromolecule Biosynthetic Process Negative Regulation Of Microtubule Depolymerization Cellular Component Assembly Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Neutrophil Differentiation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Memory T Cell Proliferation Regulation Of Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Mitotic Cell Cycle Regulation Of Microtubule Cytoskeleton Organization Developmental Process Microtubule-based Process Leukocyte Cell-cell Adhesion Negative Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		a549 anticancer chemotherapeutic clones credits effectively exposing gltscr2 lats1 making mdr1 nf1 paclitaxel panel predetermined profiling pten regards screen screened shrna shrnas smad4 st14 suppressors tumorigenesis tumorigenic vhl wt1	c6ofr49 c6orf49 ccnd2 ccnd3 ccne1 cdk6 cdkn1a cdkn1b cdkn2a cdkn2b cdkn2c cdkn2d datasets disequilibrium frs3 genotyped heredity kip1 p15 p18 p19 p33 participating pgc rs2479717 tagging tags trfp usp49
Tagcloud (Difference) ?		a549 anticancer chemotherapeutic clones credits effectively exposing gltscr2 lats1 making mdr1 nf1 paclitaxel panel predetermined profiling pten regards screen screened shrna shrnas smad4 st14 suppressors tumorigenesis tumorigenic vhl wt1	c6ofr49 c6orf49 ccnd2 ccnd3 ccne1 cdk6 cdkn1a cdkn1b cdkn2a cdkn2b cdkn2c cdkn2d datasets disequilibrium frs3 genotyped heredity kip1 p15 p18 p19 p33 participating pgc rs2479717 tagging tags trfp usp49
Tagcloud (Intersection) ?