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GCC1 and ABI2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
GCC1
ABI2
Gene Name
GRIP and coiled-coil domain containing 1
abl-interactor 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Cytoplasm
Golgi Apparatus
Plasma Membrane
Cytoplasm
Cytosol
Cytoskeleton
Lamellipodium
Filopodium
SCAR Complex
Molecular Function
Protein Binding
DNA Binding
Protein Binding
Cytoskeletal Adaptor Activity
SH3 Domain Binding
Kinase Binding
Ubiquitin Protein Ligase Binding
Protein Complex Binding
Rac GTPase Binding
Proline-rich Region Binding
Biological Process
Protein Targeting To Golgi
Movement Of Cell Or Subcellular Component
Cytoskeleton Organization
Actin Polymerization Or Depolymerization
Cell Migration
Rac Protein Signal Transduction
Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Signaling by VEGF
Fcgamma receptor (FCGR) dependent phagocytosis
VEGFA-VEGFR2 Pathway
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Drugs
Diseases
GWAS
Type 2 diabetes (
22158537
)
Butyrylcholinesterase levels (
21862451
)
Subclinical atherosclerosis traits (other) (
17903303
)
Protein-Protein Interactions
36 interactors:
ABI2
AMOTL2
APP
ARL1
ATF4
ATN1
BIRC2
BRCA1
C1orf94
CCDC85B
CEP57
CEP70
COIL
CPSF7
DNAJA3
FBF1
GLI1
GOLGA2
GTF2I
IKBKG
ITSN1
KIAA0753
KIAA1217
LZTS2
MCRS1
NAB2
NAV1
NECAB2
NINL
OIP5
PAK7
SMARCD1
TFIP11
TRIM29
USHBP1
ZNF276
57 interactors:
ABL1
ADAM19
AES
ARHGAP32
ARMC7
BLOC1S6
CCDC102B
CCDC36
CCDC53
CCHCR1
CDK6
CRX
DTNB
EFS
EGLN3
EIF3H
ENAH
GCC1
HGS
HNRNPK
HOMER3
IFT20
KHDRBS1
KIAA1217
KIFC3
KRT13
KRT15
KRT19
KRT20
KRT31
KRT33B
LMO2
MRFAP1L1
MRPL44
NCK2
NUP62
PCM1
PIN1
PPIF
PRAM1
PRKAA1
PRKAA2
PRR16
SDCBP
SH3KBP1
SNAP23
STAM2
TFIP11
TRAF3IP1
TRIM32
TRIP6
VARS2
VASP
VCL
VPS37C
WASF2
WIPF1
Entrez ID
79571
10152
HPRD ID
07599
07338
Ensembl ID
ENSG00000179562
ENSG00000138443
Uniprot IDs
A4D0Z4
Q96CN9
E9PEZ7
Q9NYB9
PDB IDs
2ED0
3P8C
Enriched GO Terms of Interacting Partners
?
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Organelle Organization
Transcription, DNA-templated
RNA Metabolic Process
Regulation Of Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Intracellular Signal Transduction
Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Anatomical Structure Development
Developmental Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Toxin Metabolic Process
Negative Regulation Of Cell Death
Mitotic Cell Cycle
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase III Promoter
Nitrogen Compound Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Ubiquitination
Cell Communication
Positive Regulation Vascular Endothelial Growth Factor Production
Signal Transduction
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
System Development
Multicellular Organismal Development
Cellular Process
NIK/NF-kappaB Signaling
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Biosynthetic Process
Cell Cycle
Positive Regulation Of Histone H4-K20 Methylation
Spliceosomal Complex Disassembly
Positive Regulation Of Histone H4-K16 Acetylation
Positive Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Protein Monoubiquitination
Positive Regulation Of Protein K48-linked Ubiquitination
Intracellular Transport
Organelle Organization
Cell Projection Assembly
Establishment Of Localization In Cell
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Movement Of Cell Or Subcellular Component
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Response To Stimulus
Negative Regulation Of ERBB Signaling Pathway
Negative Regulation Of Intracellular Signal Transduction
Cytoskeleton Organization
Negative Regulation Of Signaling
Cellular Localization
Cellular Component Assembly
Regulation Of Signal Transduction
Cell Projection Morphogenesis
Cellular Response To Stimulus
Developmental Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Surface Receptor Signaling Pathway
Cell Part Morphogenesis
Cell Cycle Arrest
Cell Projection Organization
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Signaling
Actin Cytoskeleton Organization
System Development
Actin Filament-based Process
Anatomical Structure Development
Signaling
Intraciliary Transport
Cell Morphogenesis
Membrane Organization
Generation Of Neurons
Cell Communication
Regulation Of Autophagy
Enzyme Linked Receptor Protein Signaling Pathway
Multicellular Organismal Development
Protein Localization
Protein Transport
Neurogenesis
Lamellipodium Assembly
Signal Transduction
Lamellipodium Organization
Establishment Of Protein Localization
Negative Regulation Of Cellular Senescence
Microtubule-based Transport
Tagcloud
?
aba
abscisic
arabidopsis
aux1
auxin
axr4
crosstalk
ein2
eir1
elongation
ethylene
eto1
formed2
genotyping
germination
insensitive
insensitive2
operate
overproducer1
pin
pin2
positional
resistant1
resistant4
responsiveness
root
root1
seed
thaliana
Tagcloud (Difference)
?
aba
abscisic
arabidopsis
aux1
auxin
axr4
crosstalk
ein2
eir1
elongation
ethylene
eto1
formed2
genotyping
germination
insensitive
insensitive2
operate
overproducer1
pin
pin2
positional
resistant1
resistant4
responsiveness
root
root1
seed
thaliana
Tagcloud (Intersection)
?