VTN and GLUD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		VTN	GLUD1
Gene Name		vitronectin	glutamate dehydrogenase 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome Alphav-beta3 Integrin-vitronectin Complex Blood Microparticle	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Scavenger Receptor Activity Integrin Binding Protein Binding Heparin Binding Polysaccharide Binding Extracellular Matrix Binding	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding
	Biological Process	Receptor-mediated Endocytosis Immune Response Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Endopeptidase Activity Positive Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Blood Coagulation Extracellular Matrix Organization Regulation Of Complement Activation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Binding Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Innate Immune Response Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Wound Healing	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process Tricarboxylic Acid Metabolic Process
Pathways		Molecules associated with elastic fibres Syndecan interactions Regulation of Complement cascade Complement cascade Elastic fibre formation ECM proteoglycans Integrin cell surface interactions Non-integrin membrane-ECM interactions Innate Immune System	Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives
Drugs		Abciximab	L-Glutamic Acid NADH Hexachlorophene Nicotinamide-Adenine-Dinucleotide Adenosine-5\'-Diphosphate Guanosine-5\'-Triphosphate
Diseases
GWAS
Protein-Protein Interactions		42 interactors: ADH5 ADTRP AMPH APP CBX1 CD247 CKS2 COPS5 CRADD CSNK2A1 EGF ETV7 FGF2 FGG GEM GLUD1 GOPC HGF IGF2 IGFBP5 ITGA8 ITGB3 ITGB6 ITGB8 KNG1 LACRT PLAUR POMC PRDX4 PRKACA PRKCA PRKCB PRKCG PVR RHOXF1 RPL13A SERPINE1 SIX1 TGFB1 TGFB2 TNFRSF11B VEGFA	11 interactors: ASGR2 CRP DYNLL1 GOT2 HPX LSM1 NR4A1 ORM1 SEC62 STAT5A VTN
Entrez ID		7448	2746
HPRD ID		01902	11748
Ensembl ID			ENSG00000148672
Uniprot IDs		D9ZGG2 P04004	B3KV55 E9KL48 P00367
PDB IDs		1OC0 1S4G 1SSU 2JQ8 3BT1 3BT2	1L1F 1NR1
Enriched GO Terms of Interacting Partners?		Platelet Activation Platelet Degranulation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Extracellular Matrix Organization Extracellular Structure Organization Cell Activation Exocytosis Signaling Cell Communication Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Response To External Stimulus Secretion Secretion By Cell Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Endothelial Cell Migration Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Epithelial Cell Proliferation Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Phosphorylation Response To Stimulus Cellular Response To Stimulus Positive Regulation Of Angiogenesis Regulation Of Protein Kinase Activity Positive Regulation Of MAPK Cascade Cellular Localization Positive Regulation Of Metabolic Process Regulation Of Signaling Positive Regulation Of Cell Migration Response To Stress Positive Regulation Of Cell Motility Regulation Of MAPK Cascade Regulation Of Kinase Activity Histone H3-T6 Phosphorylation Regulation Of Epithelial Cell Migration Regulation Of Cellular Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Intracellular Signal Transduction	Regulation Of Immune System Process 2-oxoglutarate Metabolic Process Regulation Of Immune Response Oxaloacetate Metabolic Process Transport Acute-phase Response Endocytosis Regulation Of Humoral Immune Response Positive Regulation Of Mast Cell Differentiation Receptor-mediated Endocytosis Acute Inflammatory Response Dicarboxylic Acid Metabolic Process Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Regulation Of Mast Cell Differentiation Fumarate Metabolic Process Development Of Secondary Male Sexual Characteristics Immune System Process Aspartate Catabolic Process 4-hydroxyproline Catabolic Process Positive Regulation Of Interferon-gamma-mediated Signaling Pathway Hormone-mediated Signaling Pathway Response To Ethanol Negative Regulation Of Mast Cell Apoptotic Process L-kynurenine Metabolic Process Creatinine Metabolic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response Regulation Of Mast Cell Apoptotic Process Positive Regulation Of Mast Cell Proliferation Positive Regulation Of Immune Response Glutamate Catabolic Process Isoleucine Metabolic Process Allantoin Metabolic Process Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Vesicle-mediated Transport Positive Regulation Of Innate Immune Response Taurine Metabolic Process Aspartate Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Posttranslational Protein Targeting To Membrane Negative Regulation Of Vasodilation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Erythrocyte Differentiation Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Prolactin Signaling Pathway Regulation Of Peptidyl-tyrosine Phosphorylation
Tagcloud ?		accumulated aeamsq aeamsqv aeamsqvt aeamsqvtn aeamsqvtntatim desorption dimeric dimerization dissociated exclusion flight immunoblot maldi monomeric nonapeptide p17gag p24gag p2gag potently pr55gag protease proteolytic spectrometric sqnypivq succinyl suicide tof vtntatim	alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud2 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily
Tagcloud (Difference) ?		accumulated aeamsq aeamsqv aeamsqvt aeamsqvtn aeamsqvtntatim desorption dimeric dimerization dissociated exclusion flight immunoblot maldi monomeric nonapeptide p17gag p24gag p2gag potently pr55gag protease proteolytic spectrometric sqnypivq succinyl suicide tof vtntatim	alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud2 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily
Tagcloud (Intersection) ?