VTN and AMPH

Number of citations of the paper that reports this interaction (PMID 12565847)
2

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		VTN	AMPH
Gene Name		vitronectin	amphiphysin
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome Alphav-beta3 Integrin-vitronectin Complex Blood Microparticle	Synaptic Vesicle Actin Cytoskeleton Cell Junction Synaptic Vesicle Membrane Leading Edge Membrane
	Molecular Function	Scavenger Receptor Activity Integrin Binding Protein Binding Heparin Binding Polysaccharide Binding Extracellular Matrix Binding	Protein Binding Phospholipid Binding
	Biological Process	Receptor-mediated Endocytosis Immune Response Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Endopeptidase Activity Positive Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Blood Coagulation Extracellular Matrix Organization Regulation Of Complement Activation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Binding Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Innate Immune Response Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Wound Healing	Endocytosis Synaptic Transmission Learning Synaptic Vesicle Endocytosis
Pathways		Molecules associated with elastic fibres Syndecan interactions Regulation of Complement cascade Complement cascade Elastic fibre formation ECM proteoglycans Integrin cell surface interactions Non-integrin membrane-ECM interactions Innate Immune System
Drugs		Abciximab
Diseases
GWAS
Protein-Protein Interactions		42 interactors: ADH5 ADTRP AMPH APP CBX1 CD247 CKS2 COPS5 CRADD CSNK2A1 EGF ETV7 FGF2 FGG GEM GLUD1 GOPC HGF IGF2 IGFBP5 ITGA8 ITGB3 ITGB6 ITGB8 KNG1 LACRT PLAUR POMC PRDX4 PRKACA PRKCA PRKCB PRKCG PVR RHOXF1 RPL13A SERPINE1 SIX1 TGFB1 TGFB2 TNFRSF11B VEGFA	27 interactors: AP1B1 AP2A1 AP2A2 ARL16 BIN1 CABIN1 CCDC67 CDK1 CDK5 CDK5R1 CLTC DNM1 DNM2 DYRK1A ITSN2 KHDRBS1 MAPK6 NECAP1 PLD2 PPP3CC SH3GL2 SH3GLB1 SYN1 SYNJ1 TERF1 UBC VTN
Entrez ID		7448	273
HPRD ID		01902	02687
Ensembl ID			ENSG00000078053
Uniprot IDs		D9ZGG2 P04004	P49418
PDB IDs		1OC0 1S4G 1SSU 2JQ8 3BT1 3BT2	1KY7 1UTC 3SOG 4ATM
Enriched GO Terms of Interacting Partners?		Platelet Activation Platelet Degranulation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Extracellular Matrix Organization Extracellular Structure Organization Cell Activation Exocytosis Signaling Cell Communication Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Response To External Stimulus Secretion Secretion By Cell Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Endothelial Cell Migration Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Epithelial Cell Proliferation Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Phosphorylation Response To Stimulus Cellular Response To Stimulus Positive Regulation Of Angiogenesis Regulation Of Protein Kinase Activity Positive Regulation Of MAPK Cascade Cellular Localization Positive Regulation Of Metabolic Process Regulation Of Signaling Positive Regulation Of Cell Migration Response To Stress Positive Regulation Of Cell Motility Regulation Of MAPK Cascade Regulation Of Kinase Activity Histone H3-T6 Phosphorylation Regulation Of Epithelial Cell Migration Regulation Of Cellular Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Intracellular Signal Transduction	Endocytosis Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Receptor Metabolic Process Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Recycling Receptor-mediated Endocytosis Synaptic Vesicle Transport Receptor Internalization Regulation Of Signaling Synaptic Transmission Axon Guidance Peptidyl-threonine Phosphorylation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of ERBB Signaling Pathway Neuron Projection Morphogenesis Positive Regulation Of Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Axonogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Neuron Projection Development Axon Development Regulation Of Signal Transduction Cell Projection Morphogenesis Establishment Of Vesicle Localization Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Defense Response To Virus By Virus Positive Regulation Of Apoptotic Process Regulation Of Vesicle-mediated Transport Positive Regulation Of Programmed Cell Death Cell Part Morphogenesis Chemotaxis Vesicle Localization Regulation Of Cellular Component Organization Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Hyaluronan Biosynthetic Process Cellular Localization Positive Regulation Of Cell Death Ephrin Receptor Signaling Pathway Regulation Of Cell Cycle Arrest Neurotrophin Signaling Pathway Establishment Of Localization In Cell
Tagcloud ?		accumulated aeamsq aeamsqv aeamsqvt aeamsqvtn aeamsqvtntatim desorption dimeric dimerization dissociated exclusion flight immunoblot maldi monomeric nonapeptide p17gag p24gag p2gag potently pr55gag protease proteolytic spectrometric sqnypivq succinyl suicide tof vtntatim	10a 10as 6b 6br 7h amphetamine antipsychotic butan cataleptogenic demonstrable dimethoxy headtwitch hexahydro histaminergic ht2a ht2c hydrochloride hyperlocomotion id50 iodoamphetamine mesocortical mesolimbic microdialysis neurotransmission pyrido pyrrolo quinoxalin sert unwanted
Tagcloud (Difference) ?		accumulated aeamsq aeamsqv aeamsqvt aeamsqvtn aeamsqvtntatim desorption dimeric dimerization dissociated exclusion flight immunoblot maldi monomeric nonapeptide p17gag p24gag p2gag potently pr55gag protease proteolytic spectrometric sqnypivq succinyl suicide tof vtntatim	10a 10as 6b 6br 7h amphetamine antipsychotic butan cataleptogenic demonstrable dimethoxy headtwitch hexahydro histaminergic ht2a ht2c hydrochloride hyperlocomotion id50 iodoamphetamine mesocortical mesolimbic microdialysis neurotransmission pyrido pyrrolo quinoxalin sert unwanted
Tagcloud (Intersection) ?