VTN and ETV7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		VTN	ETV7
Gene Name		vitronectin	ets variant 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome Alphav-beta3 Integrin-vitronectin Complex Blood Microparticle	Nucleus Nucleoplasm
	Molecular Function	Scavenger Receptor Activity Integrin Binding Protein Binding Heparin Binding Polysaccharide Binding Extracellular Matrix Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding
	Biological Process	Receptor-mediated Endocytosis Immune Response Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Endopeptidase Activity Positive Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Blood Coagulation Extracellular Matrix Organization Regulation Of Complement Activation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Binding Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Innate Immune Response Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Wound Healing	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Organ Morphogenesis Cell Differentiation
Pathways		Molecules associated with elastic fibres Syndecan interactions Regulation of Complement cascade Complement cascade Elastic fibre formation ECM proteoglycans Integrin cell surface interactions Non-integrin membrane-ECM interactions Innate Immune System
Drugs		Abciximab
Diseases
GWAS
Protein-Protein Interactions		42 interactors: ADH5 ADTRP AMPH APP CBX1 CD247 CKS2 COPS5 CRADD CSNK2A1 EGF ETV7 FGF2 FGG GEM GLUD1 GOPC HGF IGF2 IGFBP5 ITGA8 ITGB3 ITGB6 ITGB8 KNG1 LACRT PLAUR POMC PRDX4 PRKACA PRKCA PRKCB PRKCG PVR RHOXF1 RPL13A SERPINE1 SIX1 TGFB1 TGFB2 TNFRSF11B VEGFA	4 interactors: IRF4 L3MBTL1 LRPAP1 VTN
Entrez ID		7448	51513
HPRD ID		01902	16095
Ensembl ID			ENSG00000010030
Uniprot IDs		D9ZGG2 P04004	Q9Y603
PDB IDs		1OC0 1S4G 1SSU 2JQ8 3BT1 3BT2
Enriched GO Terms of Interacting Partners?		Platelet Activation Platelet Degranulation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Extracellular Matrix Organization Extracellular Structure Organization Cell Activation Exocytosis Signaling Cell Communication Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Response To External Stimulus Secretion Secretion By Cell Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Endothelial Cell Migration Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Epithelial Cell Proliferation Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Phosphorylation Response To Stimulus Cellular Response To Stimulus Positive Regulation Of Angiogenesis Regulation Of Protein Kinase Activity Positive Regulation Of MAPK Cascade Cellular Localization Positive Regulation Of Metabolic Process Regulation Of Signaling Positive Regulation Of Cell Migration Response To Stress Positive Regulation Of Cell Motility Regulation Of MAPK Cascade Regulation Of Kinase Activity Histone H3-T6 Phosphorylation Regulation Of Epithelial Cell Migration Regulation Of Cellular Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Intracellular Signal Transduction	Regulation Of Binding Positive Regulation Of Binding Positive Regulation Of Interleukin-13 Biosynthetic Process Regulation Of Protein Binding Positive Regulation Of Interleukin-10 Biosynthetic Process Positive Regulation Of Interleukin-4 Biosynthetic Process Negative Regulation Of Beta-amyloid Clearance Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Regulation Of Immune System Process T-helper 17 Cell Lineage Commitment T-helper 17 Cell Differentiation Regulation Of Beta-amyloid Clearance Receptor-mediated Endocytosis Cell Adhesion Mediated By Integrin T-helper Cell Lineage Commitment Positive Regulation Of Interleukin-2 Biosynthetic Process Positive Regulation Of Interleukin-13 Production CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune System Process Extracellular Negative Regulation Of Signal Transduction Regulation Of Megakaryocyte Differentiation Chromatin Modification Smooth Muscle Cell-matrix Adhesion Defense Response To Protozoan Positive Regulation Of Interleukin-4 Production Regulation Of Cell Adhesion Regulation Of Interleukin-2 Biosynthetic Process Hemopoiesis T Cell Lineage Commitment Myeloid Dendritic Cell Differentiation Negative Regulation Of Receptor Activity Endocytosis Negative Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Smooth Muscle Cell Migration Response To Protozoan Myeloid Dendritic Cell Activation Positive T Cell Selection T-helper Cell Differentiation Immune System Development Positive Regulation Of Interleukin-10 Production Chromatin Organization Regulation Of Hematopoietic Progenitor Cell Differentiation Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Interleukin-4 Production Regulation Of Complement Activation Regulation Of T-helper Cell Differentiation Regulation Of Signal Transduction Positive Regulation Of Interleukin-2 Production Endodermal Cell Differentiation
Tagcloud ?		accumulated aeamsq aeamsqv aeamsqvt aeamsqvtn aeamsqvtntatim desorption dimeric dimerization dissociated exclusion flight immunoblot maldi monomeric nonapeptide p17gag p24gag p2gag potently pr55gag protease proteolytic spectrometric sqnypivq succinyl suicide tof vtntatim	3a 5mum 5ng annotation correlating crosstalk doxo dusp5 fc fluoruracil inducer lamp3 log2 mcf7 microenvironment modify nfkappab ntn1 nutlin opposite plk3 proof qpcr repressed snai1 synergistically tnfalpha transcriptome unc5b
Tagcloud (Difference) ?		accumulated aeamsq aeamsqv aeamsqvt aeamsqvtn aeamsqvtntatim desorption dimeric dimerization dissociated exclusion flight immunoblot maldi monomeric nonapeptide p17gag p24gag p2gag potently pr55gag protease proteolytic spectrometric sqnypivq succinyl suicide tof vtntatim	3a 5mum 5ng annotation correlating crosstalk doxo dusp5 fc fluoruracil inducer lamp3 log2 mcf7 microenvironment modify nfkappab ntn1 nutlin opposite plk3 proof qpcr repressed snai1 synergistically tnfalpha transcriptome unc5b
Tagcloud (Intersection) ?