GLUD1

Gene Name		glutamate dehydrogenase 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding
	Biological Process	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process Tricarboxylic Acid Metabolic Process
Pathways		Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives
Drugs		L-Glutamic Acid NADH Hexachlorophene Nicotinamide-Adenine-Dinucleotide Adenosine-5\'-Diphosphate Guanosine-5\'-Triphosphate
Diseases
GWAS
Protein-protein Interactions		11 interactors: ASGR2 CRP DYNLL1 GOT2 HPX LSM1 NR4A1 ORM1 SEC62 STAT5A VTN
Entrez ID		2746
HPRD ID		11748
Ensembl ID		ENSG00000148672
Uniprot IDs		B3KV55 E9KL48 P00367
PDB IDs		1L1F 1NR1
Enriched GO Terms of Interacting Partners?		Regulation Of Immune System Process 2-oxoglutarate Metabolic Process Regulation Of Immune Response Oxaloacetate Metabolic Process Transport Acute-phase Response Endocytosis Regulation Of Humoral Immune Response Positive Regulation Of Mast Cell Differentiation Receptor-mediated Endocytosis Acute Inflammatory Response Dicarboxylic Acid Metabolic Process Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Regulation Of Mast Cell Differentiation Fumarate Metabolic Process Development Of Secondary Male Sexual Characteristics Immune System Process Aspartate Catabolic Process 4-hydroxyproline Catabolic Process Positive Regulation Of Interferon-gamma-mediated Signaling Pathway Hormone-mediated Signaling Pathway Response To Ethanol Negative Regulation Of Mast Cell Apoptotic Process L-kynurenine Metabolic Process Creatinine Metabolic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response Regulation Of Mast Cell Apoptotic Process Positive Regulation Of Mast Cell Proliferation Positive Regulation Of Immune Response Glutamate Catabolic Process Isoleucine Metabolic Process Allantoin Metabolic Process Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Vesicle-mediated Transport Positive Regulation Of Innate Immune Response Taurine Metabolic Process Aspartate Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Posttranslational Protein Targeting To Membrane Negative Regulation Of Vasodilation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Erythrocyte Differentiation Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Prolactin Signaling Pathway Regulation Of Peptidyl-tyrosine Phosphorylation
Tagcloud ?		alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud2 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily