GLUD1 and ASGR2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GLUD1	ASGR2
Gene Name		glutamate dehydrogenase 1	asialoglycoprotein receptor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Integral Component Of Membrane
	Molecular Function	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process Tricarboxylic Acid Metabolic Process	Receptor-mediated Endocytosis Cell Surface Receptor Signaling Pathway Glycoprotein Metabolic Process Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis
Pathways		Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives
Drugs		L-Glutamic Acid NADH Hexachlorophene Nicotinamide-Adenine-Dinucleotide Adenosine-5\'-Diphosphate Guanosine-5\'-Triphosphate
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ASGR2 CRP DYNLL1 GOT2 HPX LSM1 NR4A1 ORM1 SEC62 STAT5A VTN	7 interactors: ASGR1 CERS2 F8 GLUD1 HES1 MROH5 VKORC1
Entrez ID		2746	433
HPRD ID		11748	00152
Ensembl ID		ENSG00000148672	ENSG00000161944
Uniprot IDs		B3KV55 E9KL48 P00367	P07307 Q7Z4G9
PDB IDs		1L1F 1NR1
Enriched GO Terms of Interacting Partners?		Regulation Of Immune System Process 2-oxoglutarate Metabolic Process Regulation Of Immune Response Oxaloacetate Metabolic Process Transport Acute-phase Response Endocytosis Regulation Of Humoral Immune Response Positive Regulation Of Mast Cell Differentiation Receptor-mediated Endocytosis Acute Inflammatory Response Dicarboxylic Acid Metabolic Process Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Regulation Of Mast Cell Differentiation Fumarate Metabolic Process Development Of Secondary Male Sexual Characteristics Immune System Process Aspartate Catabolic Process 4-hydroxyproline Catabolic Process Positive Regulation Of Interferon-gamma-mediated Signaling Pathway Hormone-mediated Signaling Pathway Response To Ethanol Negative Regulation Of Mast Cell Apoptotic Process L-kynurenine Metabolic Process Creatinine Metabolic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response Regulation Of Mast Cell Apoptotic Process Positive Regulation Of Mast Cell Proliferation Positive Regulation Of Immune Response Glutamate Catabolic Process Isoleucine Metabolic Process Allantoin Metabolic Process Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Vesicle-mediated Transport Positive Regulation Of Innate Immune Response Taurine Metabolic Process Aspartate Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Posttranslational Protein Targeting To Membrane Negative Regulation Of Vasodilation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Erythrocyte Differentiation Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Prolactin Signaling Pathway Regulation Of Peptidyl-tyrosine Phosphorylation	Midbrain Development Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Negative Regulation Of Forebrain Neuron Differentiation Negative Regulation Of Auditory Receptor Cell Differentiation Inhibition Of Neuroepithelial Cell Differentiation Negative Regulation Of Pro-B Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Auditory Receptor Cell Fate Determination Trochlear Nerve Development Ascending Aorta Morphogenesis Positive Regulation Of Mitotic Cell Cycle, Embryonic Oculomotor Nerve Development Regulation Of Pro-B Cell Differentiation Regulation Of Auditory Receptor Cell Differentiation STAT Protein Import Into Nucleus Glutamate Catabolic Process Regulation Of Forebrain Neuron Differentiation Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis Regulation Of Mitotic Cell Cycle, Embryonic Regulation Of Timing Of Neuron Differentiation Forebrain Radial Glial Cell Differentiation Vitamin K Metabolic Process Comma-shaped Body Morphogenesis Common Bile Duct Development Metanephric Nephron Tubule Morphogenesis Midbrain-hindbrain Boundary Morphogenesis Renal Interstitial Fibroblast Development Glutamate Biosynthetic Process S-shaped Body Morphogenesis Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Neuron Fate Determination Auditory Receptor Cell Fate Commitment Negative Regulation Of Epidermal Cell Differentiation Positive Regulation Of Astrocyte Differentiation Radial Glial Cell Differentiation Vascular Smooth Muscle Cell Development Negative Regulation Of Glial Cell Proliferation Regulation Of Secondary Heart Field Cardioblast Proliferation Dicarboxylic Acid Catabolic Process Metanephric Tubule Morphogenesis Peptidyl-glutamic Acid Carboxylation Midbrain-hindbrain Boundary Development Adenohypophysis Development Blood Coagulation, Intrinsic Pathway Oxidation-reduction Process Blood Coagulation Metanephric Nephron Tubule Development
Tagcloud ?		alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud2 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily
Tagcloud (Difference) ?		alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud2 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily
Tagcloud (Intersection) ?