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VIM and MEN1
Number of citations of the paper that reports this interaction (PubMedID
12169273
)
0
Data Source:
HPRD
(in vitro, in vivo)
VIM
MEN1
Description
vimentin
menin 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Peroxisome
Microtubule Organizing Center
Cytosol
Cytoskeleton
Intermediate Filament
Plasma Membrane
Focal Adhesion
Membrane
Nuclear Matrix
Axon
Cell Leading Edge
Cell Projection
Neuron Projection
Intermediate Filament Cytoskeleton
Phagocytic Vesicle
Extracellular Exosome
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum Lumen
Cytosol
Nuclear Matrix
Transcription Repressor Complex
Cleavage Furrow
Protein-containing Complex
Histone Methyltransferase Complex
MLL1/2 Complex
MLL1 Complex
Molecular Function
RNA Binding
Double-stranded RNA Binding
Structural Constituent Of Cytoskeleton
Structural Constituent Of Eye Lens
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Molecular Adaptor Activity
Scaffold Protein Binding
Keratin Filament Binding
Four-way Junction DNA Binding
Y-form DNA Binding
Transcription Cis-regulatory Region Binding
DNA Binding
Chromatin Binding
Double-stranded DNA Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Phosphoprotein Binding
R-SMAD Binding
Biological Process
Positive Regulation Of Gene Expression
Negative Regulation Of Neuron Projection Development
Astrocyte Development
Neuron Projection Development
Positive Regulation Of Collagen Biosynthetic Process
Regulation Of MRNA Stability
Intermediate Filament-based Process
Intermediate Filament Organization
Bergmann Glial Cell Differentiation
Lens Fiber Cell Development
Cellular Response To Lipopolysaccharide
Cellular Response To Muramyl Dipeptide
Cellular Response To Type II Interferon
Negative Regulation Of Transcription By RNA Polymerase II
MAPK Cascade
Negative Regulation Of Protein Phosphorylation
Osteoblast Development
DNA Repair
Chromatin Organization
Regulation Of Transcription By RNA Polymerase II
DNA Damage Response
Negative Regulation Of Cell Population Proliferation
Response To UV
Response To Gamma Radiation
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of DNA-binding Transcription Factor Activity
T-helper 2 Cell Differentiation
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Cell Cycle
Transcription Initiation-coupled Chromatin Remodeling
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of JNK Cascade
Pathways
Caspase-mediated cleavage of cytoskeletal proteins
Striated Muscle Contraction
Interleukin-4 and Interleukin-13 signaling
RHOBTB1 GTPase cycle
Chaperone Mediated Autophagy
Late endosomal microautophagy
Aggrephagy
Developmental Lineage of Mammary Gland Myoepithelial Cells
Formation of the beta-catenin:TCF transactivating complex
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Deactivation of the beta-catenin transactivating complex
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
RHO GTPases activate IQGAPs
Post-translational protein phosphorylation
Formation of WDR5-containing histone-modifying complexes
Drugs
Artenimol
Phenethyl Isothiocyanate
Diseases
Primary hyperparathyroidism; Familial hyperparathyroidism (HRPT)
Adrenal carcinoma
Malignant islet cell carcinoma
Carcinoid
GWAS
Aspartate aminotransferase levels (
33547301
)
Cholesterol, total (
24097068
)
HDL cholesterol levels (
32203549
)
Mean spheric corpuscular volume (
32888494
)
Total cholesterol levels (
28334899
)
Triglyceride levels (
32203549
)
Urate levels (
21768215
)
Interacting Genes
188 interacting genes:
ABLIM1
AKT1
ANKRD35
ANXA7
APIP
APLP1
APP
ARMC7
ARMCX2
ATN1
BAG4
BFSP1
BHLHE40
BRD1
BYSL
CAMK2D
CAPN1
CASP3
CASP6
CASP7
CASP8
CASP9
CATSPERT
CBX8
CCDC187
CDH5
CDK1
CDKN1A
CEP126
CHD3
COPS6
CRCT1
CREB1
CRMP1
CT55
CWF19L2
DCTN1
DEFB1
DIS3L2
DNM1L
DPPA4
DSCAM
DSP
DUX4
DYNLL1
ENTR1
EPB41L2
ESS2
EXOSC7
FABP4
FAM107A
FAM118B
FAM161A
FUBP1
FXR1
FXR2
GADD45A
GEM
GFAP
GOPC
GRB2
GSK3B
HABP4
HAP1
HMG20B
HSPB1
HTRA2
ING5
IP6K1
ITGB4
IVNS1ABP
KARS1
KAT7
KIAA0408
KIF15
KIF9
KIFC3
KRT20
LGALS14
LINC01554
LORICRIN
LRIF1
MAFG
MAN2A2
MCPH1
MEN1
MICAL1
MRPL44
MTDH
NEFL
NEIL3
NFATC2
NFKBID
NIF3L1
NME2
NOC4L
NR1H2
NUP85
NXF1
OGT
OSBP2
PAK2
PDLIM1
PIAS4
PKD1
PKN1
PKP1
PKP2
PLA2G2A
PLA2G4A
PLEC
PLK1
PNMA5
POLR1C
PPHLN1
PPL
PPP1R18
PRKACA
PRPF6
PRPH
PSMA1
PSMC5
PSMD7
PSME1
PUF60
RAB8B
RABAC1
RAD51
RBM11
RBM22
RBM48
RIBC2
ROCK1
RPA1
SCNM1
SERBP1
SETDB1
SFPQ
SH3GL3
SH3YL1
SHANK3
SIRPA
SIRT6
SLC25A6
SLC27A6
SMAD3
SMARCB1
SNW1
SRRT
STX1A
SUMO2
SUMO3
SYN1
TAB2
TCEA2
TCHP
TLE5
TNFRSF14
TNNT1
TRIM14
TRIM15
TRIM28
TRIM29
TRIOBP
TSC1
TSC22D1
TTR
TUBA1C
TUBGCP4
TXLNB
TXN
TXN2
UBC
UPP1
UPP2
UROD
USP7
UTP14A
WBP11
WDR59
WHR1
XRCC4
YAE1
YWHAE
YWHAZ
ZHX1
ZNF384
ZNF572
31 interacting genes:
ANXA1
ASH2L
CTNNB1
DAXX
DBF4
ESR1
FANCD2
FOXN3
GFAP
H3-4
IQGAP1
JUND
KMT2A
KMT2D
MYC
MYH9
NFKB1
NFKB2
POLR2B
RBBP5
RELA
RPA2
SIN3A
SMAD1
SMAD3
SMAD5
SNW1
TCF3
TCF7L2
TP53
VIM
Entrez ID
7431
4221
HPRD ID
01899
00564
Ensembl ID
ENSG00000026025
ENSG00000133895
Uniprot IDs
P08670
V9HWE1
A0A5F9ZHS3
A0AA75I0P0
E7EN32
O00255
Q9GZQ5
PDB IDs
1GK4
1GK6
1GK7
3G1E
3KLT
3S4R
3SSU
3SWK
3TRT
3UF1
4MCY
4MCZ
4MD0
4MD5
4MDI
4MDJ
4YPC
4YV3
5WHF
6ATF
6ATI
6BIR
6YXK
8RVE
8TRQ
8TRR
3U84
3U85
3U86
3U88
4GPQ
4GQ3
4GQ4
4GQ6
4I80
4OG3
4OG4
4OG5
4OG6
4OG7
4OG8
4X5Y
4X5Z
5DB0
5DB1
5DB2
5DB3
5DD9
5DDA
5DDB
5DDC
5DDD
5DDE
5DDF
6B41
6BXH
6BXY
6BY8
6E1A
6O5I
6OPJ
6PKC
6S2K
6WNH
7M4T
7O9T
7O9X
7O9Z
7OA9
7UJ4
8E90
8GPN
8IG0
8VA5
8VA6
9C92
9C93
9C94
Enriched GO Terms of Interacting Partners
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Nucleus
Nucleoplasm
Cytoplasm
Identical Protein Binding
Regulation Of Protein Localization To Nucleus
Protein Binding
Regulation Of Protein Localization
Negative Regulation Of Metabolic Process
Structural Constituent Of Cytoskeleton
Cytoskeleton
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Centrosome
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Intermediate Filament Organization
RNA Binding
Regulation Of RNA Metabolic Process
Execution Phase Of Apoptosis
Regulation Of Gene Expression
Positive Regulation Of Nucleocytoplasmic Transport
Response To Stress
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Organelle Organization
Nucleic Acid Metabolic Process
Cellular Response To Stress
Macromolecule Metabolic Process
Programmed Cell Death
Cytoskeleton Organization
Cell Death
Negative Regulation Of RNA Metabolic Process
Ubiquitin Protein Ligase Binding
Regulation Of Programmed Cell Death
Cytosol
Intermediate Filament
Apoptotic Process
Positive Regulation Of Protein Localization
Regulation Of Cell Differentiation
Positive Regulation Of Protein Export From Nucleus
Negative Regulation Of Transcription By RNA Polymerase II
Cornified Envelope
Regulation Of Protein Export From Nucleus
Regulation Of Multicellular Organismal Process
Positive Regulation Of Cell Differentiation
Transcription Regulator Complex
Nucleoplasm
Nucleus
Positive Regulation Of Macromolecule Biosynthetic Process
Chromatin
Positive Regulation Of Biosynthetic Process
DNA Binding
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Metabolic Process
Transcription Cis-regulatory Region Binding
DNA-binding Transcription Factor Activity
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Metabolic Process
Regulation Of Cell Differentiation
Regulation Of Metabolic Process
Regulation Of MiRNA Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Gene Expression
Positive Regulation Of Cell Differentiation
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of MiRNA Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Developmental Process
Ubiquitin Protein Ligase Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Response To Growth Factor
Cellular Developmental Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of MiRNA Transcription
Regulation Of Nucleobase-containing Compound Metabolic Process
Intracellular Signal Transduction
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
I-SMAD Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Nuclear Receptor Binding
Positive Regulation Of Developmental Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Primary Metabolic Process
Enzyme Binding
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Macromolecule Biosynthetic Process
Transcription Coactivator Binding
Regulation Of Cell Population Proliferation
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
DNA-templated Transcription
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Tagcloud (Intersection)
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